Carolin Siech, Reha-Baris Incesu, Simone Morra, Lukas Scheipner, Andrea Baudo, Letizia Maria Ippolita Jannello, Mario de Angelis, Jordan A Goyal, Zhe Tian, Fred Saad, Shahrokh F Shariat, Derya Tilki, Nicola Longo, Luca Carmignani, Ottavio de Cobelli, Sascha Ahyai, Alberto Briganti, Philipp Mandel, Luis A Kluth, Felix K H Chun, Pierre I Karakiewicz
INTRODUCTION: It is unknown whether the benefit from partial nephrectomy regarding lower other-cause mortality is applicable to older patients with metastatic renal cell carcinoma. MATERIALS AND METHODS: Using Surveillance Epidemiology and End Results database, patients with metastatic renal cell carcinoma, undergoing partial or radical nephrectomy, were stratified according to age (<60, 60-69, and ≥70 years). After propensity score matching, Kaplan-Meier survival analyses and multivariable Cox regression models were used...
February 13, 2024: Surgical Oncology
Alexandre Carvalho, Nuno Gonçalves, Pedro Teixeira, André Goulart, Pedro Leão
PURPOSE: In patients with colorectal cancer (CRC), the most important factor to decide the need of adjuvant chemotherapy is the histological lymph node (LN) evaluation. Our work aimed to give a broad view over the use of methylene blue and its consequences in the number of lymph node harvest. METHODS: PUBMED, WEB OF SCIENCE and EMBASE databases were consulted, retrieving clinical trials, which mentioned the used of intra-arterial methylene blue in patients with colorectal cancer...
February 9, 2024: Surgical Oncology
Ruiya Ma, Yoshinaga Okugawa, Tadanobu Shimura, Shinji Yamashita, Yuhki Sato, Chengzeng Yin, Ryo Uratani, Takahito Kitajima, Hiroki Imaoka, Mikio Kawamura, Yuhki Morimoto, Yoshiki Okita, Shigeyuki Yoshiyama, Masaki Ohi, Yuji Toiyama
PURPOSE: The C-reactive protein-albumin-lymphocyte (CALLY) index is a novel inflammatory nutritional biomarker. This study aimed to investigate the potential clinical significance and oncological prognostic role of the preoperative CALLY index in patients with esophageal cancer. METHODS: We analyzed the preoperative CALLY index in 146 patients with esophageal cancer. The CALLY index and clinicopathological variables were analyzed by the Mann-Whitney U test, and associations between the CALLY index and survival outcomes were analyzed by Kaplan-Meier analysis and log-rank tests...
February 5, 2024: Surgical Oncology
Elisabeth R M van Haaren, Merel A Spiekerman van Weezelenburg, James van Bastelaar, Alfred Janssen, Thiemo van Nijnatten, Lee H Bouwman, Yvonne L J Vissers, Marc B I Lobbes
BACKGROUND: Residual particles of superparamagnetic iron oxide (SPIO) tracer, used for sentinel node biopsy, cause susceptibility artefacts on breast Magnetic Resonance Imaging (MRI). We investigated the impact of these artefacts on the imaging quality of MRI and explored whether contrast-enhanced mammography (CEM) could be an alternative in the follow-up of breast cancer patients. MATERIALS AND METHODS: Data on patients' characteristics, injection site, presence, size (mm) of artefacts on full-field digital mammography (FFDM)/CEM, MRI after 1 ml SPIO was recorded...
February 5, 2024: Surgical Oncology
Kyohei Abe, Kenei Furukawa, Michinori Matsumoto, Yasuro Futagawa, Hironori Shiozaki, Shinji Onda, Koichiro Haruki, Yoshihiro Shirai, Tomoyoshi Okamoto, Toru Ikegami
AIM: To study the effect of preoperative osteosarcopenia (OSP) on the prognosis of treatment (surgery or radiofrequency ablation (RFA)) in patients with Barcelona Cancer Liver Classification stage A hepatocellular carcinoma (BCLC A HCC). METHODS: This study enrolled 102 patients with BCLC A HCC who underwent surgical resection (n = 45) and RFA (n = 57); the patients were divided into two groups: OSP (n = 33) and non-OSP (n = 69)...
February 2, 2024: Surgical Oncology
Yoshio Masuda, Eugene Kwong Fei Leong, Jimmy Bok Yan So, Asim Shabbir, Timothy Lam Jia Wei, Daryl Kai Ann Chia, Guowei Kim
BACKGROUND: Transhiatal esophagectomy (THE) avoids thoracotomy but sacrifices mediastinal lymphadenectomy. Mediastinoscopy-assisted transhiatal esophagectomy (MATHE) allows for visualisation and en-bloc dissection of mediastinal lymph nodes while retaining the benefits of THE. However, given its novel inception, there is a paucity of literature. This study aimed to conduct the first meta-analysis to explore the efficacy of MATHE and clarify its role in the future of esophagectomy. METHODS: Four databases (PubMed, EMBASE, Scopus, and Cochrane Library) were searched from inception to May 1, 2023...
February 1, 2024: Surgical Oncology
Katsuya Sakashita, Shimpei Otsuka, Katsuhiko Uesaka, Teiichi Sugiura
BACKGROUND: Hepatic vein reconstruction (HVR) is occasionally necessary for resecting hepatic malignancies to ensure surgical margins while preserving remnant liver function [1]. Reports of multiple HVR are rare due to the highly technical demanding procedure and high risk of morbidity [2]. We introduce our procedure of double HVR for metastatic liver tumors invading the right hepatic vein (RHV) and middle hepatic vein (MHV). METHODS: The patient was a 66-year-old man with colorectal liver metastasis in segment 8, invading RHV and MHV...
January 30, 2024: Surgical Oncology
Vijay P Khatri
No abstract text is available yet for this article.
January 27, 2024: Surgical Oncology
Adela Rojas-Holguín, Constantino Fondevila-Campo, Alfonso Sanjuanbenito, Joan Fabregat-Prous, Luís Secanella-Medayo, Fernando Rotellar-Sastre, Fernando Pardo-Sánchez, Mikel Prieto-Calvo, Héctor Marín-Ortega, Santiago Sánchez-Cabús, Luis Diez-Valladares, Óscar Alonso-Casado, Carmen González-Serrano, Juan Carlos Rodríguez-Sanjuan, Gabriel García-Plaza, Isabel Jaén-Torrejimeno, Miguel Ángel Suárez-Muñoz, Antonio Becerra-Massare, Paula Senra-Del Rio, Elizabeth Pando, Rafael López-Andújar, Elena Muñoz-Forner, Mario Rodriguez-López, Fernando Pereira, Alejandro Serrablo-Requejo, Víctor Sánchez Turrión, Manuel Jiménez Garrido, Fernando Burdío, Elena Martín-Pérez, Rafael Estevan-Estevan, Diego López-Guerra, José Castell-Gómez, Javier Salinas-Gómez, José Ángel López-Baena, Santiago López-Ben, Lorena Solar-García, Alejandro J Pérez-Alonso, Luis Alberto Martínez-Insfran, Juan Luis Blas, Marian Cornejo, Alberto Gutierrez-Calvo, Carlos Domingo-Del Pozo, Federico Ochando-Cerdan, Luis Muñoz-Bellvís, José Rebollar-Saenz, Belinda Sánchez, José María Jover, Miguel Ángel Gómez-Bravo, José M Ramia, Gerardo Blanco-Fernández
BACKGROUND AND OBJECTIVES: Recurrent isolated pancreatic metastasis from Renal Cell Carcinoma (RCC) after pancreatic resection is rare. The purpose of our study is to describe a series of cases of relapse of pancreatic metastasis from renal cancer in the pancreatic remnant and its surgical treatment with a repeated pancreatic resection, and to analyse the results of both overall and disease-free survival. METHODS: Multicenter retrospective study of patients undergoing pancreatic resection for RCC pancreatic metastases, from January 2010 to May 2020...
January 27, 2024: Surgical Oncology
Umut Kina Kilicaslan, Basak Aru, Sibel Aydin Aksu, Fugen Vardar Aker, Gulderen Yanikkaya Demirel, Meryem Gunay Gurleyik
INTRODUCTION: Following major developments in cancer immunotherapy, treatments targeting immune checkpoint proteins (ICP) gained interest in breast cancer, though studies mostly focus on patients with metastatic disease as well as patients nonresponsive to the conventional treatments. Herein, we aimed to investigate the levels of ICP in tumor stroma and tumor infiltrating lymphocytes, and tumor tissue prior to neoadjuvant chemotherapy administration to evaluate the relationship between ICP levels, clinicopathological parameters, and NAC response...
January 24, 2024: Surgical Oncology
Jorge Cabrolier, Oscar Ceballos, Fabiola Rieloff, Francisco Hardoy, Ricardo Tolosa, Orlando Wevar
INTRODUCTION: The femur is frequently affected by primary and metastatic bone tumors. In cases with substantial bone loss, Total Femur Replacement (TFR) remains the only viable limb preservation option. This study investigates the clinical outcomes of TFR patients in a Latin American setting, with a minimum 3-year follow-up. METHODS: Retrospective review identifying cases of TFR at a single center from 2009 to 2020. Patients who had TFR either due to oncological indications or complications arising from oncology-related surgeries were included...
January 22, 2024: Surgical Oncology
Sameh Hany Emile, Nir Horesh, Michael R Freund, Emanuela Silva-Alvarenga, Zoe Garoufalia, Rachel Gefen, Steven D Wexner
BACKGROUND: This study aimed to determine predictors of overall survival (OS) after surgical treatment of stage I-III appendiceal adenocarcinoma and compare the outcomes of partial colectomy and hemicolectomy. METHODS: A retrospective analysis of the U.S. National Cancer Database (NCDB) including patients who underwent surgery for stage I-III appendiceal adenocarcinoma between 2005 and 2019 was conducted. A propensity-score matched analysis was undertaken to compare the outcomes of partial and hemicolectomy and multivariate analysis was performed to determine predictive factors of OS...
January 5, 2024: Surgical Oncology
Narayana Subramaniam, Gillian Heller, Jonathan Robert Clark, Ruta Gupta, David Goldstein, John R de Almeida, Ali Hosni, Deepak Balasubramanian, Krishnakumar Thankappan, Subramania Iyer, Martin Batstone, N Gopal Iyer, Robert I Smee, Naveen Hedne Chandrasekhar, Vijay Pillai, Vivek Shetty, Vidyabhushan Rangappa, Michael Veness, Tsu-Hui Hubert Low
BACKGROUND: Despite introduction of extranodal extension (ENE) into the AJCC 8th edition of oral cancer staging, previous criticisms persist, such as limited discrimination between sub-stages and doubtful prognostic value of contralateral nodal disease. The purpose of this study was to compare our novel nodal staging system, based on the number of positive nodes and ENE, to the AJCC staging system in surgically treated patients. METHODS: Retrospective analysis of 4710 patients with oral squamous cell carcinoma (OSCC) treated with surgery±adjuvant therapy in 8 institutions in Australia, North America and Asia...
January 5, 2024: Surgical Oncology
Norimitsu Okui, Masashi Tsunematsu, Kenei Furukawa, Yoshihiiro Shirai, Koichiro Haruki, Taro Sakamoto, Tadashi Uwagawa, Shinji Onda, Takeshi Gocho, Toru Ikegami
AIM: Pancreatic ductal adenocarcinoma treatment is mainly based on the anatomical resectability classification. However, prognosis-based classification may be more reasonable. In this study, we stratified resectable pancreatic ductal adenocarcinoma according to preoperative factors and reconsidered treatment strategies. METHODS: We retrospectively evaluated 131 patients who underwent upfront surgery for resectable pancreatic ductal adenocarcinoma between 2007 and 2019...
January 5, 2024: Surgical Oncology
Osman Can, Eyyüp Danış, Eren Görkem Kutlutürk, Emre Can Polat, Alper Ötünçtemur
INTRODUCTION: A clear consensus has not yet been reached on the optimal ureteroenteric anastomosis technique for ileal conduit urinary diversion following radical cystectomy. This study aims to determine the incidence of strictures and their management associated with these anastomosis techniques. METHODS: We conducted a retrospective, single-center study of patients who underwent radical cystectomy and urinary diversion between March 2014 and August 2022. Patients were categorized based on the ureteroenteric anastomosis technique used: Wallace, Bricker, or Hybrid...
January 5, 2024: Surgical Oncology
Moon Usman, Peter Yao, Kathleen Luckett, Katerina Andreadis, Remil Thomas, Andy Hickner, Paul J Christos, Andrew Tassler, David Kutler, William Kuhel, Victoria Banuchi
OBJECTIVE: With the growing global incidence of thyroid carcinomas, there is an increasing need for distinct guidelines for isthmus-confined carcinomas. Here, we performed the first systematic review on the topic to date, aiming to provide understanding to isthmusectomy as surgical management for well-differentiated thyroid carcinoma of the isthmus. METHODS: We conducted a systematic review following the PRISMA guidelines, analyzing English-language studies from the past decade that report on thyroid isthmusectomy...
December 27, 2023: Surgical Oncology
Erhan Okay, Marcos R Gonzalez, Joseph O Werenski, Alisha Sodhi, Korhan Ozkan, Marcus Brookes, Maniram Ragbir, Kenneth Rankin, Anand Tn Kumar, Santiago A Lozano-Calderon
BACKGROUND: Fluorescence-guided surgery (FGS) is a novel technique to successfully assess surgical margins intraoperatively. Investigation and adoption of this technique in orthopaedic oncology remains limited. METHODS: The PRISMA guidelines were followed for this manuscript. Our study was registered on PROSPERO (380520). Studies describing the use of FGS for resection of bone and soft tissue sarcomas (STS) on humans were included. Diagnostic performance metrics (sensitivity, specificity, positive predictive value [PPV], negative predictive value [NPV] and accuracy) and margin positivity rate were the outcomes assessed...
December 22, 2023: Surgical Oncology
Leva Gorji, Zachary J Brown, Timothy M Pawlik
Hepatocellular carcinoma (HCC) and cholangiocarcinoma (CCA) comprise the two most common primary liver malignancies. Curative treatment options often include hepatectomy or liver transplantation; however, many patients present with advanced disease that is not amenable to surgical management. In turn, many patients are treated with systemic or targeted therapy. The tumor microenvironment (TME) is a complex network of immune cells and somatic cells, which can foster an environment for disease development and progression, as well as susceptibility and resistance to systemic therapeutic agents...
December 18, 2023: Surgical Oncology
Sebastian G Walter, Jan Hockmann, Maximilian Weber, Nikolaus Kernich, Peter Knöll, Kourosh Zarghooni
BACKGROUND: While predictors for postoperative survival in spine tumour patients have been identified, there is limited evidence for predictors of postoperative Quality of Life (QoL), pain and functional outcome. METHODS: One hundred and fifty-three consecutive patients, who had undergone surgery for symptomatic spinal metastases between June 2016 and April 2019, were interviewed preoperatively and during follow-ups at three, six and 12 months using the EQ-5D-3L, COMI, and ODI questionnaires...
December 16, 2023: Surgical Oncology
Nicole J Andersen, Kedar K B Mate, Catherine Bergeron, Robert Turcotte, Annett Körner
INTRODUCTION: Soft-tissue sarcoma (STS) is a rare cancer of the connective tissues requiring invasive treatment. Due to the complexity of treatment, STS patients experience more functional impairment and disability than other oncologic populations. Given that extant literature is unclear and exclusively focused on physical function, the objectives of this study were to use the Wilson-Cleary Model of HRQL to evaluate the extent to which biological function (tumor site, depth and size), symptoms (fatigue, pain, anxiety/depression), and functional status are associated with the health perceptions of soft-tissue sarcoma patients 12 months post-op...
December 15, 2023: Surgical Oncology
Fetch more papers »
Fetching more papers... Fetching...
Remove bar
Read by QxMD icon Read

Save your favorite articles in one place with a free QxMD account.


Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"

We want to hear from doctors like you!

Take a second to answer a survey question.