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JOURNAL ARTICLE
Adela Rojas-Holguín, Constantino Fondevila-Campo, Alfonso Sanjuanbenito, Joan Fabregat-Prous, Luís Secanella-Medayo, Fernando Rotellar-Sastre, Fernando Pardo-Sánchez, Mikel Prieto-Calvo, Héctor Marín-Ortega, Santiago Sánchez-Cabús, Luis Diez-Valladares, Óscar Alonso-Casado, Carmen González-Serrano, Juan Carlos Rodríguez-Sanjuan, Gabriel García-Plaza, Isabel Jaén-Torrejimeno, Miguel Ángel Suárez-Muñoz, Antonio Becerra-Massare, Paula Senra-Del Rio, Elizabeth Pando, Rafael López-Andújar, Elena Muñoz-Forner, Mario Rodriguez-López, Fernando Pereira, Alejandro Serrablo-Requejo, Víctor Sánchez Turrión, Manuel Jiménez Garrido, Fernando Burdío, Elena Martín-Pérez, Rafael Estevan-Estevan, Diego López-Guerra, José Castell-Gómez, Javier Salinas-Gómez, José Ángel López-Baena, Santiago López-Ben, Lorena Solar-García, Alejandro J Pérez-Alonso, Luis Alberto Martínez-Insfran, Juan Luis Blas, Marian Cornejo, Alberto Gutierrez-Calvo, Carlos Domingo-Del Pozo, Federico Ochando-Cerdan, Luis Muñoz-Bellvís, José Rebollar-Saenz, Belinda Sánchez, José María Jover, Miguel Ángel Gómez-Bravo, José M Ramia, Gerardo Blanco-Fernández
BACKGROUND AND OBJECTIVES: Recurrent isolated pancreatic metastasis from Renal Cell Carcinoma (RCC) after pancreatic resection is rare. The purpose of our study is to describe a series of cases of relapse of pancreatic metastasis from renal cancer in the pancreatic remnant and its surgical treatment with a repeated pancreatic resection, and to analyse the results of both overall and disease-free survival. METHODS: Multicenter retrospective study of patients undergoing pancreatic resection for RCC pancreatic metastases, from January 2010 to May 2020...
January 27, 2024: Surgical Oncology
#22
JOURNAL ARTICLE
Ching-Heng Hsiao, Yen-Liang Li, Kee-Thai Kiu, Min-Hsuan Yen, Tung-Cheng Chang
BACKGROUND: Colorectal cancer (CRC) is the third most common type of cancer worldwide, and distant metastasis is frequently noted at diagnosis or follow-up. Notably, some patients with CRC can present with distant organ metastasis without any nodal involvement, which was defined as direct distant organ metastasis (DDOM). In this study, we evaluated the prognostic significance of DDOM for patients with CRC. METHODS: This study included 325 patients who had undergone primary colorectal cancer resection between August 2008 and December 2021...
April 2024: Surgical Oncology
#23
JOURNAL ARTICLE
B O Stüben, S Ahmadi, F H Saner, J Li, J P Neuhaus, J W Treckmann, D P Hoyer
BACKGROUND: Intrahepatic cholangiocarcinoma is the second most common primary liver cancer after hepatocellular carcinoma with an increasing incidence worldwide. Surgical resection is still the only potential cure, and survival rates are dismal due to disease relapse after resection and/or metastatic disease. Positive resection margins are associated with recurrence, with conflicting studies regarding the benefits of wide resection margins to reduce recurrence rates. METHODS: 126 patients with an R0 resection treated with hepatic surgery for intrahepatic cholangiocarcinoma at the Surgical Department at the Medical University Centre Essen, Germany were identified in a database and retrospectively analysed...
April 2024: Surgical Oncology
#24
JOURNAL ARTICLE
Yi-Lin Chang, Chayanee Sae-Lim, Shih-Lung Lin, Hung-Wen Lai, Hsin-I Huang, Yuan-Chieh Lai, Shou-Tung Chen, Dar-Ren Chen
BACKGROUND: Minimal-access (endoscopic or robotic-assisted) breast surgery has been increasingly performed and shown better cosmetic results. However, location of totally implantable venous access port (TIVAP) for systemic treatment at anterior chest may compromise its aesthetic benefits. Therefore, we proposed a new scarless technique for TIVAP implantation, and reported the preliminary results, learning curve, and patients-surveyed outcome. METHODS: Surgical technique of the new "scarless" TIVAP implantation was proposed...
April 2024: Surgical Oncology
#25
REVIEW
Alexandre Carvalho, Nuno Gonçalves, Pedro Teixeira, André Goulart, Pedro Leão
PURPOSE: In patients with colorectal cancer (CRC), the most important factor to decide the need of adjuvant chemotherapy is the histological lymph node (LN) evaluation. Our work aimed to give a broad view over the use of methylene blue and its consequences in the number of lymph node harvest. METHODS: PUBMED, WEB OF SCIENCE and EMBASE databases were consulted, retrieving clinical trials, which mentioned the used of intra-arterial methylene blue in patients with colorectal cancer...
April 2024: Surgical Oncology
#26
JOURNAL ARTICLE
Ruiya Ma, Yoshinaga Okugawa, Tadanobu Shimura, Shinji Yamashita, Yuhki Sato, Chengzeng Yin, Ryo Uratani, Takahito Kitajima, Hiroki Imaoka, Mikio Kawamura, Yuhki Morimoto, Yoshiki Okita, Shigeyuki Yoshiyama, Masaki Ohi, Yuji Toiyama
PURPOSE: The C-reactive protein-albumin-lymphocyte (CALLY) index is a novel inflammatory nutritional biomarker. This study aimed to investigate the potential clinical significance and oncological prognostic role of the preoperative CALLY index in patients with esophageal cancer. METHODS: We analyzed the preoperative CALLY index in 146 patients with esophageal cancer. The CALLY index and clinicopathological variables were analyzed by the Mann-Whitney U test, and associations between the CALLY index and survival outcomes were analyzed by Kaplan-Meier analysis and log-rank tests...
April 2024: Surgical Oncology
#27
REVIEW
A systematic review and meta-analysis of mediastinoscopy-assisted transhiatal esophagectomy (MATHE).
Yoshio Masuda, Eugene Kwong Fei Leong, Jimmy Bok Yan So, Asim Shabbir, Timothy Lam Jia Wei, Daryl Kai Ann Chia, Guowei Kim
BACKGROUND: Transhiatal esophagectomy (THE) avoids thoracotomy but sacrifices mediastinal lymphadenectomy. Mediastinoscopy-assisted transhiatal esophagectomy (MATHE) allows for visualisation and en-bloc dissection of mediastinal lymph nodes while retaining the benefits of THE. However, given its novel inception, there is a paucity of literature. This study aimed to conduct the first meta-analysis to explore the efficacy of MATHE and clarify its role in the future of esophagectomy. METHODS: Four databases (PubMed, EMBASE, Scopus, and Cochrane Library) were searched from inception to May 1, 2023...
April 2024: Surgical Oncology
#28
REVIEW
Shujun Li, Hang Yi, Qihao Leng, You Wu, Yousheng Mao
In the 21st century, the development of medical science has entered the era of big data, and machine learning has become an essential tool for mining medical big data. The establishment of the SEER database has provided a wealth of epidemiological data for cancer clinical research, and the number of studies based on SEER and machine learning has been growing in recent years. This article reviews recent research based on SEER and machine learning and finds that the current focus of such studies is primarily on the development and validation of models using machine learning algorithms, with the main directions being lymph node metastasis prediction, distant metastasis prediction, and prognosis-related research...
February 2024: Surgical Oncology
#29
JOURNAL ARTICLE
Sameh Hany Emile, Nir Horesh, Michael R Freund, Emanuela Silva-Alvarenga, Zoe Garoufalia, Rachel Gefen, Steven D Wexner
BACKGROUND: This study aimed to determine predictors of overall survival (OS) after surgical treatment of stage I-III appendiceal adenocarcinoma and compare the outcomes of partial colectomy and hemicolectomy. METHODS: A retrospective analysis of the U.S. National Cancer Database (NCDB) including patients who underwent surgery for stage I-III appendiceal adenocarcinoma between 2005 and 2019 was conducted. A propensity-score matched analysis was undertaken to compare the outcomes of partial and hemicolectomy and multivariate analysis was performed to determine predictive factors of OS...
February 2024: Surgical Oncology
#30
REVIEW
Moon Usman, Peter Yao, Kathleen Luckett, Katerina Andreadis, Remil Thomas, Andy Hickner, Paul J Christos, Andrew Tassler, David Kutler, William Kuhel, Victoria Banuchi
OBJECTIVE: With the growing global incidence of thyroid carcinomas, there is an increasing need for distinct guidelines for isthmus-confined carcinomas. Here, we performed the first systematic review on the topic to date, aiming to provide understanding to isthmusectomy as surgical management for well-differentiated thyroid carcinoma of the isthmus. METHODS: We conducted a systematic review following the PRISMA guidelines, analyzing English-language studies from the past decade that report on thyroid isthmusectomy...
February 2024: Surgical Oncology
#31
JOURNAL ARTICLE
Nicole J Andersen, Kedar K B Mate, Catherine Bergeron, Robert Turcotte, Annett Körner
INTRODUCTION: Soft-tissue sarcoma (STS) is a rare cancer of the connective tissues requiring invasive treatment. Due to the complexity of treatment, STS patients experience more functional impairment and disability than other oncologic populations. Given that extant literature is unclear and exclusively focused on physical function, the objectives of this study were to use the Wilson-Cleary Model of HRQL to evaluate the extent to which biological function (tumor site, depth and size), symptoms (fatigue, pain, anxiety/depression), and functional status are associated with the health perceptions of soft-tissue sarcoma patients 12 months post-op...
February 2024: Surgical Oncology
#32
REVIEW
Leva Gorji, Zachary J Brown, Timothy M Pawlik
Hepatocellular carcinoma (HCC) and cholangiocarcinoma (CCA) comprise the two most common primary liver malignancies. Curative treatment options often include hepatectomy or liver transplantation; however, many patients present with advanced disease that is not amenable to surgical management. In turn, many patients are treated with systemic or targeted therapy. The tumor microenvironment (TME) is a complex network of immune cells and somatic cells, which can foster an environment for disease development and progression, as well as susceptibility and resistance to systemic therapeutic agents...
February 2024: Surgical Oncology
#33
MULTICENTER STUDY
(no author information available yet)
BACKGROUND: Radical surgical excision may be the only curative option for patients with advanced pelvic malignancy, but concerns surrounding the functional outcomes and survivorship of patients undergoing exenterative surgery remain. This is especially important in the context of vulvovaginal resection, where patients are often younger and surgery can have a profoundly negative impact on quality of life, body image and overall wellbeing. Reconstructive procedures are an important means of mitigating these adverse effects but outcomes are poorly described...
February 2024: Surgical Oncology
#34
JOURNAL ARTICLE
Eyal Mor, Sarah Lonie, Catherine Mitchell, Michael Henderson, Angela Webb, David E Gyorki, Hayden Snow
BACKGROUND: Pleomorphic dermal sarcoma (PDS) of the scalp is a rare tumour which is usually slow growing, but occasionally displays rapid growth and has a low rate of local recurrence. Surgical resection is the mainstay of treatment, with or without radiotherapy. The aim of this study is to describe the surgical approach and the additional benefit of radiotherapy to the treatment of these patients. METHODS: Retrospective, single-centre analysis of patients with PDS of the scalp that underwent surgical resection between 2007 and 2021 (n = 24)...
February 2024: Surgical Oncology
#35
JOURNAL ARTICLE
Elena Leinert, Stefan Lukac, Lukas Schwentner, Antonia Coenen, Visnja Fink, Kristina Veselinovic, Davut Dayan, Wolfgang Janni, Thomas W P Friedl
INTRODUCTION: Axillary Ultrasound (AUS) is standard for pre-therapeutic axillary staging in early breast cancer patients. 35-75 % of the breast cancer (BC) patients with positive axillary lymph nodes receiving neoadjuvant chemotherapy (NACT) convert to pathological node negative. For those patients, axillary surgery after NACT could be de-escalated, if an accurate prediction of the pathologic nodal status following NACT was possible. This study aims to answer the question, whether AUS can be used as a reliable diagnostic tool for restaging of axillary nodal status after NACT...
February 2024: Surgical Oncology
#36
JOURNAL ARTICLE
Umut Kina Kilicaslan, Basak Aru, Sibel Aydin Aksu, Fugen Vardar Aker, Gulderen Yanikkaya Demirel, Meryem Gunay Gurleyik
INTRODUCTION: Following major developments in cancer immunotherapy, treatments targeting immune checkpoint proteins (ICP) gained interest in breast cancer, though studies mostly focus on patients with metastatic disease as well as patients nonresponsive to the conventional treatments. Herein, we aimed to investigate the levels of ICP in tumor stroma and tumor infiltrating lymphocytes, and tumor tissue prior to neoadjuvant chemotherapy administration to evaluate the relationship between ICP levels, clinicopathological parameters, and NAC response...
January 24, 2024: Surgical Oncology
#37
JOURNAL ARTICLE
Jorge Cabrolier, Oscar Ceballos, Fabiola Rieloff, Francisco Hardoy, Ricardo Tolosa, Orlando Wevar
INTRODUCTION: The femur is frequently affected by primary and metastatic bone tumors. In cases with substantial bone loss, Total Femur Replacement (TFR) remains the only viable limb preservation option. This study investigates the clinical outcomes of TFR patients in a Latin American setting, with a minimum 3-year follow-up. METHODS: Retrospective review identifying cases of TFR at a single center from 2009 to 2020. Patients who had TFR either due to oncological indications or complications arising from oncology-related surgeries were included...
January 22, 2024: Surgical Oncology
#38
JOURNAL ARTICLE
Narayana Subramaniam, Gillian Heller, Jonathan Robert Clark, Ruta Gupta, David Goldstein, John R de Almeida, Ali Hosni, Deepak Balasubramanian, Krishnakumar Thankappan, Subramania Iyer, Martin Batstone, N Gopal Iyer, Robert I Smee, Naveen Hedne Chandrasekhar, Vijay Pillai, Vivek Shetty, Vidyabhushan Rangappa, Michael Veness, Tsu-Hui Hubert Low
BACKGROUND: Despite introduction of extranodal extension (ENE) into the AJCC 8th edition of oral cancer staging, previous criticisms persist, such as limited discrimination between sub-stages and doubtful prognostic value of contralateral nodal disease. The purpose of this study was to compare our novel nodal staging system, based on the number of positive nodes and ENE, to the AJCC staging system in surgically treated patients. METHODS: Retrospective analysis of 4710 patients with oral squamous cell carcinoma (OSCC) treated with surgery±adjuvant therapy in 8 institutions in Australia, North America and Asia...
January 5, 2024: Surgical Oncology
#39
JOURNAL ARTICLE
Norimitsu Okui, Masashi Tsunematsu, Kenei Furukawa, Yoshihiiro Shirai, Koichiro Haruki, Taro Sakamoto, Tadashi Uwagawa, Shinji Onda, Takeshi Gocho, Toru Ikegami
AIM: Pancreatic ductal adenocarcinoma treatment is mainly based on the anatomical resectability classification. However, prognosis-based classification may be more reasonable. In this study, we stratified resectable pancreatic ductal adenocarcinoma according to preoperative factors and reconsidered treatment strategies. METHODS: We retrospectively evaluated 131 patients who underwent upfront surgery for resectable pancreatic ductal adenocarcinoma between 2007 and 2019...
January 5, 2024: Surgical Oncology
#40
JOURNAL ARTICLE
Osman Can, Eyyüp Danış, Eren Görkem Kutlutürk, Emre Can Polat, Alper Ötünçtemur
INTRODUCTION: A clear consensus has not yet been reached on the optimal ureteroenteric anastomosis technique for ileal conduit urinary diversion following radical cystectomy. This study aims to determine the incidence of strictures and their management associated with these anastomosis techniques. METHODS: We conducted a retrospective, single-center study of patients who underwent radical cystectomy and urinary diversion between March 2014 and August 2022. Patients were categorized based on the ureteroenteric anastomosis technique used: Wallace, Bricker, or Hybrid...
January 5, 2024: Surgical Oncology
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