journal

Pediatrics

journal
https://read.qxmd.com/read/31941760/reducing-variation-in-the-management-of-apnea-of-prematurity-in-the-intensive-care-nursery
#1
Katherine Coughlin, Michael Posencheg, Lauren Orfe, Whitney Zachritz, Jaqueline Meadow, Kesi Yang, Lori Christ
BACKGROUND: Premature infants have bradycardia and/or desaturation events due to apnea of prematurity that resolve as the infants mature. Despite American Academy of Pediatrics guidelines recommending a standard "event-free" period before discharge, length of observation in our Intensive Care Nursery was variable. By June 2018, for infants born <36 weeks' gestation in the Intensive Care Nursery, we aimed to standardize time to discharge after the last documented event at 5 days, when the baseline mean was 3...
January 15, 2020: Pediatrics
https://read.qxmd.com/read/31941759/congenital-toxoplasmosis-presenting-as-eosinophilic-encephalomyelitis-with-spinal-cord-hemorrhage
#2
Casey N Vera, W Matthew Linam, Judith A Gadde, David S Wolf, Karen Walson, Jose G Montoya, Christina A Rostad
A 4-week-old male neonate with a history of intermittent hypothermia in the newborn nursery presented with an acute onset of bilateral lower extremity paralysis and areflexia. Extensive workup demonstrated eosinophilic encephalomyelitis and multifocal hemorrhages of the brain and spinal cord. Funduscopic examination revealed bilateral chorioretinitis with macular scarring. The laboratory values were notable for peripheral eosinophilia and cerebrospinal fluid eosinophilic pleocytosis (28 white blood cells/µL, 28% eosinophils), markedly elevated protein (1214 mg/dL), and hypoglycorrhachia (20 mg/dL)...
January 15, 2020: Pediatrics
https://read.qxmd.com/read/31937606/big-data-in-the-assessment-of-pediatric-medication-safety
#3
Ann W McMahon, William O Cooper, Jeffrey S Brown, Bruce Carleton, Finale Doshi-Velez, Isaac Kohane, Jennifer L Goldman, Mark A Hoffman, Rishikesan Kamaleswaran, Michiyo Sakiyama, Shohko Sekine, Miriam C J M Sturkenboom, Mark A Turner, Robert M Califf
Big data (BD) in pediatric medication safety research provides many opportunities to improve the safety and health of children. The number of pediatric medication and device trials has increased in part because of the past 20 years of US legislation requiring and incentivizing study of the effects of medical products in children (Food and Drug Administration Modernization Act of 1997, Pediatric Rule in 1998, Best Pharmaceuticals for Children Act of 2002, and Pediatric Research Equity Act of 2003). There are some limitations of traditional approaches to studying medication safety in children...
January 14, 2020: Pediatrics
https://read.qxmd.com/read/31937605/world-travel
#4
Janine Young
No abstract text is available yet for this article.
January 14, 2020: Pediatrics
https://read.qxmd.com/read/31932361/mandatory-vaccination-in-europe
#5
Olivia M Vaz, Mallory K Ellingson, Paul Weiss, Samuel M Jenness, Azucena Bardají, Robert A Bednarczyk, Saad B Omer
BACKGROUND: Mandatory vaccination has been effective in maintaining high vaccination coverage in countries such as the United States. However, there are no peer-reviewed analyses of the association between mandates and both coverage and subsequent incidence of vaccine-preventable disease in Europe. METHODS: Using data from the European Centre for Disease Prevention and Control and the World Health Organization, we evaluated the relationship between country-level mandatory vaccination policies and (1) measles and pertussis vaccine coverage and (2) the annual incidence of these diseases in 29 European countries...
January 13, 2020: Pediatrics
https://read.qxmd.com/read/31932360/vaccination-policies-and-disease-incidence-across-the-pond-implications-for-the-united-states
#6
Sean T O'Leary, Yvonne A Maldonado
No abstract text is available yet for this article.
January 13, 2020: Pediatrics
https://read.qxmd.com/read/31924688/neuropsychological-outcomes-at-19-years-of-age-following-extremely-preterm-birth
#7
Helen O'Reilly, Samantha Johnson, Yanyan Ni, Dieter Wolke, Neil Marlow
BACKGROUND AND OBJECTIVES: Children born extremely preterm (EP) (<26 weeks' gestation) have lower cognitive scores and an increased rate of cognitive impairment compared with their term-born peers. However, the neuropsychological presentation of these EP individuals in adulthood has not been described. The aim of this study was to examine neuropsychological outcomes in early adulthood after EP birth in the 1995 EPICure cohort and to investigate if the rate of intellectual impairment changed longitudinally...
January 10, 2020: Pediatrics
https://read.qxmd.com/read/31924687/assessing-cognitive-outcomes-in-studies-of-extreme-prematurity
#8
Louis A Schmidt, Saroj Saigal
No abstract text is available yet for this article.
January 10, 2020: Pediatrics
https://read.qxmd.com/read/31919049/cognition-after-early-tonsillectomy-for-mild-osa
#9
Karen A Waters, Jasneek Chawla, Margaret-Anne Harris, Helen Heussler, Robert J Black, Alan T Cheng, Kurt Lushington
OBJECTIVES: It remains uncertain whether treatment with adenotonsillectomy for obstructive sleep apnea in children improves cognitive function. The Preschool Obstructive Sleep Apnea Tonsillectomy and Adenoidectomy study was a prospective randomized controlled study in which researchers evaluated outcomes 12 months after adenotonsillectomy compared with no surgery in preschool children symptomatic for obstructive sleep apnea. METHODS: A total of 190 children (age 3-5 years) were randomly assigned to early adenotonsillectomy (within 2 months) or to routine wait lists (12-month wait, no adenotonsillectomy [NoAT])...
January 9, 2020: Pediatrics
https://read.qxmd.com/read/31919048/a-roadmap-to-emotional-health-for-children-and-families-with-chronic-pediatric-conditions
#10
Diane M Pickles, Stacey L Lihn, Thomas F Boat, Carole Lannon
No abstract text is available yet for this article.
January 9, 2020: Pediatrics
https://read.qxmd.com/read/31919047/effect-of-tonsillectomy-on-cognition-in-preschool-children-with-sleep-disordered-breathing
#11
David O Francis, Derek J Lam
No abstract text is available yet for this article.
January 9, 2020: Pediatrics
https://read.qxmd.com/read/31915193/state-of-the-art-renal-imaging-in-children
#12
REVIEW
Bernarda Viteri, Juan S Calle-Toro, Susan Furth, Kassa Darge, Erum A Hartung, Hansel Otero
Imaging modalities for diagnosing kidney and urinary tract disorders in children have developed rapidly over the last decade largely because of advancement of modern technology. General pediatricians and neonatologists are often the front line in detecting renal anomalies. There is a lack of knowledge of the applicability, indications, and nephrotoxic risks of novel renal imaging modalities. Here we describe the clinical impact of congenital anomalies of the kidneys and urinary tract and describe pediatric-specific renal imaging techniques by providing a practical guideline for the diagnosis of kidney and urinary tract disorders...
January 8, 2020: Pediatrics
https://read.qxmd.com/read/31915192/hearing-in-schoolchildren-after-neonatal-exposure-to-a-high-dose-gentamicin-regimen
#13
Dagny Hemmingsen, Camilla Mikalsen, Alexander Rydland Hansen, Jon Widding Fjalstad, Niels Christian Stenklev, Claus Klingenberg
OBJECTIVE: To assess the association between gentamicin exposure in the neonatal period and hearing in school age. METHODS: This study included children exposed to a high-dose (6 mg/kg) gentamicin regimen as neonates (2004-2012), invited for follow-up at school age, and a healthy age-matched control group. We assessed hearing with pure tone audiometry including the extended high-frequency (EHF) range. Outcomes were average hearing thresholds in the midfrequencies (0...
January 8, 2020: Pediatrics
https://read.qxmd.com/read/31911478/addressing-low-value-care-training-the-spotlight-on-children
#14
Gerry Fairbrother, Lisa A Simpson
No abstract text is available yet for this article.
January 7, 2020: Pediatrics
https://read.qxmd.com/read/31911477/differences-in-the-receipt-of-low-value-services-between-publicly-and-privately-insured-children
#15
Kao-Ping Chua, Aaron L Schwartz, Anna Volerman, Rena M Conti, Elbert S Huang
BACKGROUND: Children frequently receive low-value services that do not improve health, but it is unknown whether the receipt of these services differs between publicly and privately insured children. METHODS: We analyzed 2013-2014 Medicaid Analytic eXtract and IBM MarketScan Commercial Claims and Encounters databases. Using 20 measures of low-value care (6 diagnostic testing measures, 5 imaging measures, and 9 prescription drug measures), we compared the proportion of publicly and privately insured children in 12 states who received low-value services at least once or twice in 2014; the proportion of publicly and privately insured children who received low-value diagnostic tests, imaging tests, and prescription drugs at least once; and the proportion of publicly and privately insured children eligible for each measure who received the service at least once...
January 7, 2020: Pediatrics
https://read.qxmd.com/read/31907292/prescription-opioid-misuse-and-risky-adolescent-behavior
#16
Devika Bhatia, Susan K Mikulich-Gilbertson, Joseph T Sakai
OBJECTIVES: Misuse of opioid medications (ie, using opioids differently than how a doctor prescribed the medication) is common among US adolescents and associated with preventable health consequences (eg, severe respiratory depression, seizures, heart failure, and death).1 New guidelines and recommendations have made providers more attuned to overprescribing and more vigilant about screening for opioid misuse.2 We hypothesized that youth who misused prescription opioids were more likely to report engaging in a broad range of other risky behaviors...
January 6, 2020: Pediatrics
https://read.qxmd.com/read/31907291/longitudinal-associations-of-12th-grade-binge-drinking-with-risky-driving-and-high-risk-drinking
#17
Federico E Vaca, Kaigang Li, Jeremy W Luk, Ralph W Hingson, Denise L Haynie, Bruce G Simons-Morton
OBJECTIVE: To study the longitudinal associations of 12th-grade binge drinking with driving while impaired (DWI), riding with an impaired driver (RWI), blackouts, extreme binge drinking, and risky driving (self-reported Checkpoints Risky Driving Scale) among emerging adults up to 4 years after leaving high school. METHODS: The data were all 7 waves (W 1 to W 7 of the NEXT Generation Health Study; a US nationally representative study ( N = 2785) with a probability cohort of 10th-graders (mean age = 16...
January 6, 2020: Pediatrics
https://read.qxmd.com/read/31900317/lung-function-of-adults-born-at-very-low-birth-weight
#18
Jun Yang, Rachel A Kingsford, John Horwood, Michael J Epton, Maureen P Swanney, Josh Stanton, Brian A Darlow
BACKGROUND: Much remains unknown about the consequences of very low birth weight (VLBW) and bronchopulmonary dysplasia (BPD) on adult lungs. We hypothesized that VLBW adults would have impaired lung function compared with controls, and those with a history of BPD would have worse lung function than those without. METHODS: At age 26 to 30 years, 226 VLBW survivors of the New Zealand VLBW cohort and 100 term controls born in 1986 underwent lung function tests including spirometry, plethysmographic lung volumes, diffusing capacity of the lung for carbon monoxide, and single-breath nitrogen washout (SBN2 )...
January 3, 2020: Pediatrics
https://read.qxmd.com/read/31900316/global-guide-a-comprehensive-global-health-education-resource-for-pediatric-program-directors
#19
REVIEW
Nicole E St Clair, Alhassan Abdul-Mumin, Sumeet L Banker, Tania Condurache, Heather Crouse, Heather Haq, Jill Helphinstine, Peter Nicholas Kazembe, Stephanie Marton, Patricia McQuilkin, Michael B Pitt, Marideth Rus, Christiana M Russ, Chuck Schubert, Gordon E Schutze, Andrew P Steenhoff, Omolara Uwemedimo, Jennifer Watts, Sabrina M Butteris
No abstract text is available yet for this article.
January 3, 2020: Pediatrics
https://read.qxmd.com/read/31896549/the-impact-of-gun-violence-on-those-already-dying-perspectives-from-a-palliative-care-physician
#20
Teresa M Vente
No abstract text is available yet for this article.
January 2, 2020: Pediatrics
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