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(no author information available yet)
No abstract text is available yet for this article.
March 8, 2019: Lancet Infectious Diseases
#2
Brett G Mitchell, Lisa Hall, Nicole White, Adrian G Barnett, Kate Halton, David L Paterson, Thomas V Riley, Anne Gardner, Katie Page, Alison Farrington, Christian A Gericke, Nicholas Graves
BACKGROUND: The hospital environment is a reservoir for the transmission of microorganisms. The effect of improved cleaning on patient-centred outcomes remains unclear. We aimed to evaluate the effectiveness of an environmental cleaning bundle to reduce health care-associated infections in hospitals. METHODS: The REACH study was a pragmatic, multicentre, randomised trial done in 11 acute care hospitals in Australia. Eligible hospitals had an intensive care unit, were classified by the National Health Performance Authority as a major hospital (public hospitals) or having more than 200 inpatient beds (private hospitals), and had a health-care-associated infection surveillance programme...
March 8, 2019: Lancet Infectious Diseases
#3
Jonathan A Otter
No abstract text is available yet for this article.
March 8, 2019: Lancet Infectious Diseases
#4
REVIEW
Kirk M Chan-Tack, Patrick R Harrington, Su-Young Choi, Laine Myers, Julian O'Rear, Shirley Seo, David McMillan, Hanan Ghantous, Debra Birnkrant, Adam I Sherwat
The development and ultimate approval of tecovirimat for the antiviral treatment of smallpox, a disease that has been eradicated from the world for nearly 40 years, required a unique regulatory approach based on the US Food and Drug Administration's Animal Rule. We summarise the regulatory pathway and describe the challenges involved.
March 7, 2019: Lancet Infectious Diseases
#5
Nathan M Krah, Adam L Hersh
No abstract text is available yet for this article.
March 7, 2019: Lancet Infectious Diseases
#6
Laila F Ibrahim, Sandy M Hopper, Francesca Orsini, Andrew J Daley, Franz E Babl, Penelope A Bryant
BACKGROUND: Outpatient parenteral antimicrobial therapy in children is common despite no evidence of its efficacy or safety from clinical trials. We aimed to compare the efficacy and safety of intravenous antibiotic therapy at home with that of standard treatment in hospital for children with moderate to severe cellulitis. METHODS: The Cellulitis at Home or Inpatient in Children from the Emergency Department (CHOICE) trial was a randomised, controlled, non-inferiority trial in children aged 6 months to 18 years who presented to the emergency department at The Royal Children's Hospital (Melbourne, VIC, Australia) with uncomplicated moderate to severe cellulitis...
March 7, 2019: Lancet Infectious Diseases
#7
(no author information available yet)
No abstract text is available yet for this article.
March 6, 2019: Lancet Infectious Diseases
#8
Cornelis H van Werkhoven, Martin Bootsma, Marc Bonten
No abstract text is available yet for this article.
March 4, 2019: Lancet Infectious Diseases
#9
Marcelo Low, Ami Neuberger, Thomas M Hooton, Manfred S Green, Raul Raz, Ran D Balicer, Ronit Almog
BACKGROUND: It is unknown whether increased use of antibiotics in a community increases the risk of acquiring antibiotic resistance by individuals living in that community, regardless of prior individual antibiotic consumption and other risk factors for antibiotic resistance. METHODS: We used a hierarchical multivariate logistic regression approach to evaluate the association between neighbourhood fluoroquinolone consumption and individual risk of colonisation or infection of the urinary tract with fluoroquinolone-resistant Escherichia coli...
March 4, 2019: Lancet Infectious Diseases
#10
Katie L Flanagan
No abstract text is available yet for this article.
March 1, 2019: Lancet Infectious Diseases
#11
Yan Li, Susan Y Chu, Chenyan Yue, Kathleen Wannemuehler, Shuyun Xie, Fubin Zhang, Yamin Wang, Yuxi Zhang, Rui Ma, Yumin Li, Zhiping Zuo, Lance Rodewald, Qiyou Xiao, Zijian Feng, Huaqing Wang, Zhijie An
BACKGROUND: In China, measles-rubella vaccine and live attenuated SA 14-14-2 Japanese encephalitis vaccine (LJEV) are recommended for simultaneous administration at 8 months of age, which is the youngest recommended age for these vaccines worldwide. We aimed to assess the effect of the co-administration of these vaccines at 8 months of age on the immunogenicity of measles-rubella vaccine. METHODS: We did a multicentre, open-label, non-inferiority, two-group randomised controlled trial in eight counties or districts in China...
March 1, 2019: Lancet Infectious Diseases
#12
Elise Launay, Christèle Gras Le Guen
No abstract text is available yet for this article.
February 28, 2019: Lancet Infectious Diseases
#13
Josephine van de Maat, Elles van de Voort, Santiago Mintegi, Alain Gervaix, Daan Nieboer, Henriette Moll, Rianne Oostenbrink
BACKGROUND: Prevalence of serious bacterial infections in children in countries in western Europe and the USA is low. Antibiotic stewardship aims at a more rational use of antibiotics but information on the frequency of antibiotic prescription to children in emergency departments is scarce. We aimed to quantify and explain variability in antibiotic prescription in children attending European paediatric emergency departments. METHODS: We did a cross-sectional, observational study of children aged between 1 month and 16 years who presented with fever to one of 28 European emergency departments on one random sampling day per month between Nov 1, 2014, and Feb 28, 2016...
February 28, 2019: Lancet Infectious Diseases
#14
Margaret A Honein, Martin S Cetron, Dana Meaney-Delman
No abstract text is available yet for this article.
February 27, 2019: Lancet Infectious Diseases
#15
(no author information available yet)
No abstract text is available yet for this article.
February 27, 2019: Lancet Infectious Diseases
#16
Kriangsak Ruchusatsawat, Pattara Wongjaroen, Arisara Posanacharoen, Isabel Rodriguez-Barraquer, Somchai Sangkitporn, Derek A T Cummings, Henrik Salje
BACKGROUND: Little is known about the historical and current risk of Zika virus infection in southeast Asia, where the mosquito vector is widespread and other arboviruses circulate endemically. Centralised Zika virus surveillance began in Thailand in January, 2016. We assessed the long-term circulation of Zika virus in Thailand. METHODS: In this observational study, we analysed data from individuals with suspected Zika virus infection who presented at hospitals throughout the country and had biological samples (serum, plasma, or urine) tested for confirmation with PCR at the National Institute of Health laboratories in Bangkok...
February 27, 2019: Lancet Infectious Diseases
#17
Eugene T Richardson, Mosoka P Fallah
No abstract text is available yet for this article.
February 21, 2019: Lancet Infectious Diseases
#18
Joseph W S Timothy, Yper Hall, Joseph Akoi-Boré, Boubacar Diallo, Thomas R W Tipton, Hilary Bower, Thomas Strecker, Judith R Glynn, Miles W Carroll
BACKGROUND: To date, epidemiological studies at the index site of the 2013-16 west African Ebola outbreak in Meliandou, Guinea, have been restricted in their scope. We aimed to determine the occurrence of previously undocumented Ebola virus disease (EVD) cases and infections, and to reconstruct transmission events. METHODS: This cross-sectional seroprevalence survey of the adult population of Meliandou used a highly specific oral fluid test and detailed interviews of all households in the village and key informants...
February 21, 2019: Lancet Infectious Diseases
#19
REVIEW
Maria E Grillet, Juan V Hernández-Villena, Martin S Llewellyn, Alberto E Paniz-Mondolfi, Adriana Tami, Maria F Vincenti-Gonzalez, Marilianna Marquez, Adriana C Mogollon-Mendoza, Carlos E Hernandez-Pereira, Juan D Plaza-Morr, Gabriella Blohm, Mario J Grijalva, Jaime A Costales, Heather M Ferguson, Philipp Schwabl, Luis E Hernandez-Castro, Poppy H L Lamberton, Daniel G Streicker, Daniel T Haydon, Michael A Miles, Alvaro Acosta-Serrano, Harry Acquattela, Maria G Basañez, Gustavo Benaim, Luis A Colmenares, Jan E Conn, Raul Espinoza, Hector Freilij, Mary C Graterol-Gil, Peter J Hotez, Hirotomo Kato, John A Lednicky, Clara E Martinez, Santiago Mas-Coma, J Glen Morris, Juan C Navarro, Jose L Ramirez, Marlenes Rodriguez, Julio A Urbina, Leopoldo Villegas, Maikell J Segovia, Hernan J Carrasco, James L Crainey, Sergio L B Luz, Juan D Moreno, Oscar O Noya Gonzalez, Juan D Ramírez, Belkisyolé Alarcón-de Noya
In the past 5-10 years, Venezuela has faced a severe economic crisis, precipitated by political instability and declining oil revenue. Public health provision has been affected particularly. In this Review, we assess the impact of Venezuela's health-care crisis on vector-borne diseases, and the spillover into neighbouring countries. Between 2000 and 2015, Venezuela witnessed a 359% increase in malaria cases, followed by a 71% increase in 2017 (411 586 cases) compared with 2016 (240 613). Neighbouring countries, such as Brazil, have reported an escalating trend of imported malaria cases from Venezuela, from 1538 in 2014 to 3129 in 2017...
February 21, 2019: Lancet Infectious Diseases
#20
(no author information available yet)
No abstract text is available yet for this article.
February 18, 2019: Lancet Infectious Diseases
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