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Lancet Infectious Diseases

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https://read.qxmd.com/read/31519542/scarlet-fever-changes-its-spots
#1
Stephan Brouwer, Jake A Lacey, Yuanhai You, Mark R Davies, Mark J Walker
No abstract text is available yet for this article.
September 10, 2019: Lancet Infectious Diseases
https://read.qxmd.com/read/31519541/emergence-of-dominant-toxigenic-m1t1-streptococcus-pyogenes-clone-during-increased-scarlet-fever-activity-in-england-a-population-based-molecular-epidemiological-study
#2
Nicola N Lynskey, Elita Jauneikaite, Ho Kwong Li, Xiangyun Zhi, Claire E Turner, Mia Mosavie, Max Pearson, Masanori Asai, Ludmila Lobkowicz, J Yimmy Chow, Julian Parkhill, Theresa Lamagni, Victoria J Chalker, Shiranee Sriskandan
BACKGROUND: Since 2014, England has seen increased scarlet fever activity unprecedented in modern times. In 2016, England's scarlet fever seasonal rise coincided with an unexpected elevation in invasive Streptococcus pyogenes infections. We describe the molecular epidemiological investigation of these events. METHODS: We analysed changes in S pyogenes emm genotypes, and notifications of scarlet fever and invasive disease in 2014-16 using regional (northwest London) and national (England and Wales) data...
September 10, 2019: Lancet Infectious Diseases
https://read.qxmd.com/read/31501008/correction-to-lancet-infect-dis-2019-published-online-aug-28-https-doi-org-10-1016-s1473-3099-19-30421-9
#3
(no author information available yet)
No abstract text is available yet for this article.
September 6, 2019: Lancet Infectious Diseases
https://read.qxmd.com/read/31501007/who-international-standard-for-anti-rubella-learning-from-its-application
#4
REVIEW
Sarah L Kempster, Neil Almond, Wayne Dimech, Liliane Grangeot-Keros, Daniela Huzly, Joseph Icenogle, Haja Sittana El Mubarak, Mick N Mulders, C Micha Nübling
The WHO international standard for anti-rubella was first established in the 1960s when clinical diagnostics were in their infancy. Since the endorsement of the first international standard for anti-rubella IgG (RUBI-1-94), new rubella vaccines have been developed and global coverage of rubella vaccination has increased. Methods used to measure concentrations of anti-rubella IgG have also evolved to rapid, high-throughput binding assays, which have replaced often cumbersome and highly technical functional assays...
September 6, 2019: Lancet Infectious Diseases
https://read.qxmd.com/read/31494017/subsequent-mortality-in-survivors-of-ebola-virus-disease-in-guinea-a-nationwide-retrospective-cohort-study
#5
Mory Keita, Boubacar Diallo, Samuel Mesfin, Abdourahmane Marega, Koumpingnin Yacouba Nebie, N'Faly Magassouba, Ahmadou Barry, Seydou Coulibaly, Boubacar Barry, Mamadou Oury Baldé, Raymond Pallawo, Sadou Sow, Alpha Oumar Bah, Mamadou Saliou Balde, Steven Van Gucht, Mandy Kader Kondé, Amadou Bailo Diallo, Mamoudou Harouna Djingarey, Ibrahima Socé Fall, Pierre Formenty, Judith R Glynn, Lorenzo Subissi
BACKGROUND: A record number of people survived Ebola virus infection in the 2013-16 outbreak in west Africa, and the number of survivors has increased after subsequent outbreaks. A range of post-Ebola sequelae have been reported in survivors, but little is known about subsequent mortality. We aimed to investigate subsequent mortality among people discharged from Ebola treatment units. METHODS: From Dec 8, 2015, Surveillance Active en ceinture, the Guinean national survivors' monitoring programme, attempted to contact and follow-up all survivors of Ebola virus disease who were discharged from Ebola treatment units...
September 4, 2019: Lancet Infectious Diseases
https://read.qxmd.com/read/31494016/increased-mortality-in-survivors-of-ebola-virus-disease
#6
Hugues Fausther-Bovendo, Gary Kobinger
No abstract text is available yet for this article.
September 4, 2019: Lancet Infectious Diseases
https://read.qxmd.com/read/31474459/enriching-the-antibiotic-armamentarium-for-acute-bacterial-skin-and-skin-structure-infections
#7
Matteo Bassetti, Elda Righi
No abstract text is available yet for this article.
August 29, 2019: Lancet Infectious Diseases
https://read.qxmd.com/read/31474458/once-daily-oral-omadacycline-versus-twice-daily-oral-linezolid-for-acute-bacterial-skin-and-skin-structure-infections-oasis-2-a-phase-3-double-blind-multicentre-randomised-controlled-non-inferiority-trial
#8
William O'Riordan, Carrie Cardenas, Elliot Shin, Alissa Sirbu, Lynne Garrity-Ryan, Anita F Das, Paul B Eckburg, Amy Manley, Judith N Steenbergen, Evan Tzanis, Paul C McGovern, Evan Loh
BACKGROUND: Pathogen resistance and safety concerns limit oral antibiotic options for the treatment of acute bacterial skin and skin structure infections (ABSSSI). We aimed to compare the efficacy and safety of once-daily oral omadacycline, an aminomethylcycline antibiotic, versus twice-daily oral linezolid for treatment of ABSSSI. METHODS: In this phase 3, double-blind, randomised, non-inferiority study, eligible adults with ABSSSI at 33 sites in the USA were randomly assigned (1:1) to receive omadacycline (450 mg orally every 24 h over the first 48 h then 300 mg orally every 24 h) or linezolid (600 mg orally every 12 h) for 7-14 days...
August 29, 2019: Lancet Infectious Diseases
https://read.qxmd.com/read/31473127/disseminated-sporotrichosis-following-iatrogenic-immunosuppression-for-suspected-pyoderma-gangrenosum
#9
REVIEW
Marissa White, La'Tonzia Adams, Casey Phan, Gulsun Erdag, Marissa Totten, Richard Lee, Xuelian Lu, Seema Mehta, Lloyd S Miller, Sean X Zhang
Sporotrichosis is an infection caused by the dimorphic fungus Sporothrix schenckii and related species that often arises from traumatic inoculation of inhabited soil and organic debris into skin. The infection is usually limited to the skin in immunocompetent patients, usually as lymphocutaneous sporotrichosis. Accurate diagnosis rests on clinical data and culture, and might be facilitated by biopsy identification of suppurative and granulomatous inflammation with fungal elements. In this Grand Round, we present a dramatic case of cutaneous sporotrichosis initially presented with an atypical large ulcer without associated lymphocutaneous spread, clinically mimicking pyoderma gangrenosum, and subsequently progressed to disseminated sporotrichosis in the setting of iatrogenic immunosuppression...
August 28, 2019: Lancet Infectious Diseases
https://read.qxmd.com/read/31471131/effectiveness-of-pre-entry-active-tuberculosis-and-post-entry-latent-tuberculosis-screening-in-new-entrants-to-the-uk-a-retrospective-population-based-cohort-study
#10
Luis C Berrocal-Almanza, Ross Harris, Maeve K Lalor, Morris C Muzyamba, John Were, Anne-Marie O'Connell, Adil Mirza, Onn-Min Kon, Ajit Lalvani, Dominik Zenner
BACKGROUND: Evaluating interventions that might lead to a reduction in tuberculosis in high-income countries with a low incidence of the disease is key to accelerate progress towards its elimination. In such countries, migrants are known to contribute a large proportion of tuberculosis cases to the burden. We assessed the effectiveness of screening for active tuberculosis before entry to the UK and for latent tuberculosis infection (LTBI) post-entry for reduction of tuberculosis in new-entrant migrants to the UK...
August 27, 2019: Lancet Infectious Diseases
https://read.qxmd.com/read/31471130/tuberculosis-testing-and-migrant-health
#11
Martin Gulliford, Aphra Garner-Purkis
No abstract text is available yet for this article.
August 27, 2019: Lancet Infectious Diseases
https://read.qxmd.com/read/31451422/simplified-control-measures-for-esbl-producing-enterobacteriacae
#12
Jean-Christophe Lucet, Jean-Ralph Zahar
No abstract text is available yet for this article.
August 23, 2019: Lancet Infectious Diseases
https://read.qxmd.com/read/31451421/non-inferiority-versus-superiority-trial-design-for-new-antibiotics-in-an-era-of-high-antimicrobial-resistance-the-case-for-post-marketing-adaptive-randomised-controlled-trials
#13
REVIEW
Simone Lanini, John P A Ioannidis, Francesco Vairo, Michel Pletschette, Gina Portella, Virginia Di Bari, Alessia Mammone, Raffaella Pisapia, Stefano Merler, Boniface Nguhuni, Martin Langer, Antonino Di Caro, Sarah J L Edwards, Nicola Petrosillo, Alimuddin Zumla, Giuseppe Ippolito
Antimicrobial resistance is one of the most important threats to global health security. A range of Gram-negative bacteria associated with high morbidity and mortality are now resistant to almost all available antibiotics. In this context of urgency to develop novel drugs, new antibiotics for multidrug-resistant Gram-negative bacteria (namely, ceftazidime-avibactam, plazomicin, and meropenem-vaborbactam) have been approved by regulatory authorities based on non-inferiority trials that provided no direct evidence of their efficacy against multidrug-resistant bacteria such as Enterobacteriaceae spp, Pseudomonas aeruginosa, Stenotrophomonas maltophilia, Burkholderia cepacia, and Acinetobacter baumannii...
August 23, 2019: Lancet Infectious Diseases
https://read.qxmd.com/read/31451420/correction-to-lancet-infect-dis-2019-published-online-aug-6-https-doi-org-10-1016-s1473-3099-19-30310-x
#14
(no author information available yet)
No abstract text is available yet for this article.
August 23, 2019: Lancet Infectious Diseases
https://read.qxmd.com/read/31451419/contact-precautions-in-single-bed-or-multiple-bed-rooms-for-patients-with-extended-spectrum-%C3%AE-lactamase-producing-enterobacteriaceae-in-dutch-hospitals-a-cluster-randomised-crossover-non-inferiority-study
#15
Marjolein F Q Kluytmans-van den Bergh, Patricia C J Bruijning-Verhagen, Christina M J E Vandenbroucke-Grauls, Els I G B de Brauwer, Anton G M Buiting, Bram M Diederen, Erika P M van Elzakker, Alex W Friedrich, Joost Hopman, Nashwan Al Naiemi, John W A Rossen, Gijs J H M Ruijs, Paul H M Savelkoul, Carlo Verhulst, Margreet C Vos, Andreas Voss, Marc J M Bonten, Jan A J W Kluytmans
BACKGROUND: Use of single-bed rooms for control of extended-spectrum β-lactamase (ESBL)-producing Enterobacteriaceae is under debate; the added value when applying contact precautions has not been shown. We aimed to assess whether an isolation strategy of contact precautions in a multiple-bed room was non-inferior to a strategy of contact precautions in a single-bed room for preventing transmission of ESBL-producing Enterobacteriaceae. METHODS: We did a cluster-randomised, crossover, non-inferiority study on medical and surgical wards of 16 Dutch hospitals...
August 23, 2019: Lancet Infectious Diseases
https://read.qxmd.com/read/31447305/improving-the-cascade-of-global-tuberculosis-care-moving-from-the-what-to-the-how-of-quality-improvement
#16
REVIEW
Bruce D Agins, Daniel J Ikeda, Michael J A Reid, Eric Goosby, Madhukar Pai, Adithya Cattamanchi
Tuberculosis is preventable, treatable, and curable, yet it has the highest mortality rate of infectious diseases worldwide. Over the past decade, services to prevent, screen, diagnose, and treat tuberculosis have been developed and scaled up globally, but progress to end the disease as a public health threat has been slow, particularly in low-income and middle-income countries. In these settings, low-quality tuberculosis prevention, diagnostic, and treatment services frustrate efforts to translate use of existing tools, approaches, and treatment regimens into improved individual and public health outcomes...
August 22, 2019: Lancet Infectious Diseases
https://read.qxmd.com/read/31439417/sales-reps-in-india-push-unnecessary-antibiotics
#17
Madlen Davies, Rahul Meesaraganda, Ben Stockton
No abstract text is available yet for this article.
August 19, 2019: Lancet Infectious Diseases
https://read.qxmd.com/read/31427174/improving-the-estimation-of-the-global-burden-of-antimicrobial-resistant-infections
#18
REVIEW
Direk Limmathurotsakul, Susanna Dunachie, Keiji Fukuda, Nicholas A Feasey, Iruka N Okeke, Alison H Holmes, Catrin E Moore, Christiane Dolecek, H Rogier van Doorn, Nandini Shetty, Alan D Lopez, Sharon J Peacock
Estimating the global burden of disease from infections caused by pathogens that have acquired antimicrobial resistance (AMR) is essential for resource allocation and to inform AMR action plans at national and global levels. However, the scarcity of robust and accepted methods to determine burden is widely acknowledged. In this Personal View, we discuss the underlying assumptions, characteristics, limitations, and comparability of the approaches used to quantify mortality from AMR bacterial infections. We show that the global burdens of AMR estimated in previous studies are not comparable because of their different methodological approaches, assumptions, and data used to generate the estimates...
August 16, 2019: Lancet Infectious Diseases
https://read.qxmd.com/read/31422014/correction-to-lancet-infect-dis-2019-19-802-03
#19
(no author information available yet)
No abstract text is available yet for this article.
August 14, 2019: Lancet Infectious Diseases
https://read.qxmd.com/read/31420293/cost-effectiveness-of-outpatient-parenteral-antibiotic-therapy-for-children-with-cellulitis
#20
Raymond Oppong, Shahela Kodabuckus
No abstract text is available yet for this article.
August 12, 2019: Lancet Infectious Diseases
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