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Journals Journal of Clinical Endocrinol...

Journal of Clinical Endocrinology and Metabolism

https://read.qxmd.com/read/33839794/hdl-containing-apolipoprotein-c-iii-is-associated-with-insulin-sensitivity-a-multi-center-cohort-study
#1
Rain Yamamoto, Majken K Jensen, Sarah Aroner, Jeremy D Furtado, Bernard Rosner, Frank B Hu, Beverley Balkau, Andrea Natali, Ele Ferrannini, Simona Baldi, Frank M Sacks
CONTEXT: HDL in humans is composed of a heterogeneous group of particles varying in protein composition as well as biological effects. OBJECTIVE: We investigated the prospective associations between HDL subspecies containing and lacking apoC-III at baseline and insulin sensitivity at year 3. DESIGN, SETTING, AND PARTICIPANTS: A prospective cohort study of 864 healthy volunteers drawn from the RISC study, a multi-center European clinical investigation, whose recruitment initiated in 2002 with a follow-up of 3 years...
April 11, 2021: Journal of Clinical Endocrinology and Metabolism
https://read.qxmd.com/read/33839790/clinical-practice-guidelines-on-the-diagnosis-and-management-of-polycystic-ovary-syndrome-a-systematic-review-and-quality-assessment-study
#2
Bassel H Al Wattar, Maria Fisher, Laura Bevington, Vikram Talaulikar, Melanie Davies, Gerrad Conway, Ephia Yasmin
CONTEXT: Clinical practice guidelines (CPGs) are key instruments to implement the practice of evidence-based medicine. We aimed to evaluate the methodological quality and variations in CPGs recommendations on the diagnosis and management of polycystic ovary syndrome (PCOS). EVIDENCE ACQUISITION: We searched MEDLINE, EMBASE, and CENTRAL until December 2020 for all evidence-based CPGs and consensus statements on PCOS. We extracted data in duplicate to map clinical recommendations across pre-specified disease domains and assessed CPGs methodological quality of using the AGREE II tool...
April 11, 2021: Journal of Clinical Endocrinology and Metabolism
https://read.qxmd.com/read/33839787/preoperative-amlodipine-is-efficacious-in-preventing-intraoperative-hdi-in-pheochromocytoma-pilot-rct
#3
Sanjeet Kumar Jaiswal, Saba Samad Memon, Anurag Lila, Vijaya Sarathi, Manjunath Goroshi, Robin Garg, Rohit Barnabas, Indrani Hemantkumar, Rajendra D Patel, Shrikanta Oak, Abhay Dalvi, Mahadeo Garale, Virendra Patil, Nalini S Shah, Tushar Bandgar
BACKGROUND: Preoperative blockade with α-blockers is recommended in patients with pheochromocytoma/paraganglioma (PPGL). The data on calcium channel blockade (CCB) in PPGL is scarce. We aimed to compare the efficacy of CCB and α-blockers on intraoperative haemodynamic instability (HDI) in PPGL. METHODS: In the interim analysis of this monocentric, pilot, open-label, randomized controlled trial, patients with solitary, secretory, and nonmetastatic PPGL were randomized to oral prazosin GITS (maximum 30mg, n=9) or amlodipine (maximum 20mg, n=11)...
April 11, 2021: Journal of Clinical Endocrinology and Metabolism
https://read.qxmd.com/read/33839769/adolescent-tri-ponderal-mass-index-growth-trajectories-and-incident-diabetes-mellitus-in-early-adulthood
#4
Yi-Fan Wu, Hsien-Yu Fan, Yang-Ching Chen, Kuan-Liang Kuo, Kuo-Liong Chien
PURPOSE: Studies have reported the influence of adolescent obesity on development of adult diabetes, but the effect of the growth pattern during this period has rarely been explored. Also, the tri-ponderal mass index (TMI) was thought to be a better estimation of adolescent body fat levels than the body mass index (BMI), so we sought to investigate whether growth trajectories derived by these two indices could predict incident diabetes. METHODS: We conducted a study by using the Taipei City Hospital Radiation Building Database, a longitudinal cohort established from 1996 until now...
April 11, 2021: Journal of Clinical Endocrinology and Metabolism
https://read.qxmd.com/read/33838046/cushing-blues
#5
Alicia Santos, Susan M Webb
No abstract text is available yet for this article.
April 10, 2021: Journal of Clinical Endocrinology and Metabolism
https://read.qxmd.com/read/33837783/serum-inflammation-based-scores-in-endocrine-tumors
#6
Pedro Marques, Friso de Vries, Olaf M Dekkers, Márta Korbonits, Nienke R Biermasz, Alberto M Pereira
CONTEXT: Serum inflammation-based scores reflect systemic inflammatory response and/or patients' nutritional status, and may predict clinical outcomes in cancer. While these are well-described and increasingly used in different cancers, their clinical usefulness in the management of patients with endocrine tumors is less known. EVIDENCE ACQUISITION: A comprehensive PubMed search was performed using the terms "endocrine tumor", "inflammation", "serum inflammation-based score", "inflammatory-based score", "inflammatory response-related scoring", "systemic inflammatory response markers", "Neutrophil-to-lymphocyte ratio", "Neutrophil-to-platelet ratio", "Lymphocyte-to-monocyte ratio", "Glasgow Prognostic Score", "Neutrophil-Platelet Score", "Systemic Immune-Inflammation Index", and "Prognostic Nutrition Index" in clinical studies...
April 10, 2021: Journal of Clinical Endocrinology and Metabolism
https://read.qxmd.com/read/33837779/predictive-value-of-serum-lipid-for-intravenous-immunoglobulin-resistance-and-coronary-artery-lesion-in-kawasaki-disease
#7
Shuran Shao, Kaiyu Zhou, Xiaoliang Liu, Lei Liu, Mei Wu, Yuxin Deng, Hongyu Duan, Yifei Li, Yimin Hua, Chuan Wang
CONTEXT: Intravenous immunoglobulin (IVIG) resistance and coronary artery lesions (CALs) prediction are pivotal topic of interests in Kawasaki disease (KD). However, data on the predictive value of lipid profile for both IVIG resistance and CALs are limited. PURPOSE: To investigate the predictive validity of lipid profile for IVIG resistance and CALs in KD. DESIGN: Prospective cohort study. SETTING: West China Second University Hospital...
April 10, 2021: Journal of Clinical Endocrinology and Metabolism
https://read.qxmd.com/read/33837415/new-horizons-addressing-healthcare-disparities-in-endocrine-disease-bias-science-and-patient-care
#8
Marshall H Chin
Unacceptable healthcare disparities in endocrine disease have persisted for decades, and 2021 presents a difficult evolving environment. The COVID-19 pandemic has highlighted the gross structural inequities that drive health disparities, and anti-racism demonstrations remind us that the struggle for human rights continues. Increased public awareness and discussion of disparities present an urgent opportunity to advance health equity. However, it is more complicated to change the behavior of individuals and reform systems because societies are polarized into different factions that increasingly believe, accept, and live different realities...
April 10, 2021: Journal of Clinical Endocrinology and Metabolism
https://read.qxmd.com/read/33837396/letter-to-the-editor-from-thaer-idrees-md-treatment-of-thyroid-dysfunction-and-serum-lipids-a-systematic-review-and-meta-analysis
#9
Thaer Idrees, Antonio C Bianco
No abstract text is available yet for this article.
April 10, 2021: Journal of Clinical Endocrinology and Metabolism
https://read.qxmd.com/read/33837395/response-to-letter-to-the-editor-from-idrees-and-bianco-treatment-of-thyroid-dysfunction-and-serum-lipids-a-systematic-review-and-meta-analysis
#10
Anupam Kotwal, M Hassan Murad, Fares Alahdab
No abstract text is available yet for this article.
April 10, 2021: Journal of Clinical Endocrinology and Metabolism
https://read.qxmd.com/read/33830242/psychological-distress-and-sleep-disturbance-throughout-thyroid-nodules-screening-diagnosis-and-treatment
#11
Ruicen Li, Genpeng Li, Yuting Wang, Ting Bao, Yali Lei, Liuyan Tian, Zhihui Li, Jingqiang Zhu, Jianyong Lei, Huairong Tang
BACKGROUND: Many controversies exist regarding screening and treatment of thyroid cancer (TC), especially papillary thyroid microcarcinoma (PTMC). The aim of this study was to evaluate patients' psychological distress and sleep disturbance throughout thyroid nodules (TNs) screening, diagnosis and treatment. MATERIALS AND METHODS: A total of 2834 participants (1153 participants with TNs) were enrolled during the screening phase, and 1105 individuals with TNs (87 individuals with TC) were enrolled during the diagnosis phase...
April 8, 2021: Journal of Clinical Endocrinology and Metabolism
https://read.qxmd.com/read/33830237/clinical-and-hormonal-profiles-correlate-with-molecular-characteristics-in-patients-with-11%C3%AE-hydroxylase-deficiency
#12
Melek Yildiz, Emregul Isik, Zehra Yavas Abali, Mehmet Keskin, Mehmet Nuri Ozbek, Firdevs Bas, Seyit Ahmet Ucakturk, Muammer Buyukinan, Hasan Onal, Cengiz Kara, Karl-Heinz Storbeck, Feyza Darendeliler, Atilla Cayir, Edip Unal, Ahmet Anik, Huseyin Demirbilek, Tugba Cetin, Fatma Dursun, Gonul Catli, Serap Turan, Henrik Falhammar, Tugba Baris, Ali Yaman, Goncagul Haklar, Abdullah Bereket, Tulay Guran
BACKGROUND: Given the rarity of 11β-hydroxylase deficiency (11βOHD), there is a paucity of data about the differences in clinical and biochemical characteristics of classic (C-11βOHD) and non-classic 11βOHD (NC-11βOHD). OBJECTIVE: To characterize a multicenter pediatric cohort with 11βOHD. METHOD: The clinical and biochemical characteristics were retrospectively retrieved. CYP11B1 gene sequencing was performed. Seventeen plasma steroids were quantified by liquid chromatography-mass spectrometry and compared to that of controls...
April 8, 2021: Journal of Clinical Endocrinology and Metabolism
https://read.qxmd.com/read/33829264/rates-of-conversion-of-testosterone-to-estradiol-may-influence-risk-of-venous-thromboembolism-in-men
#13
Bu B Yeap
No abstract text is available yet for this article.
April 8, 2021: Journal of Clinical Endocrinology and Metabolism
https://read.qxmd.com/read/33824990/maternal-adiposity-and-energy-balance-after-normotensive-and-preeclamptic-pregnancies
#14
Sarah L McLennan, Amanda Henry, Lynne M Roberts, Sai S Siritharan, Melissa Ojurovic, Amanda Yao, Gregory K Davis, George Mangos, Franziska Pettit, Mark A Brown, Anthony J O'Sullivan
BACKGROUND: Preeclampsia is a major pregnancy complication associated with long-term maternal cardiometabolic disease. Research generally is focused on metabolic and pathophysiological changes during pregnancy, however, there is much less focus on the early postpartum period in subjects who suffered preeclampsia. The aim of this study was to (a) characterise energy intake and expenditure six months following normotensive and preeclamptic pregnancies, and (b) examine associations between energy balance, body composition, insulin resistance measures (HOMA-IR), and clinical characteristics...
April 7, 2021: Journal of Clinical Endocrinology and Metabolism
https://read.qxmd.com/read/33824988/successful-delivery-in-17-20-lyase-deficiency
#15
Zeev Blumenfeld, Ilana Koren
OBJECTIVE: To study and describe the achievement of successful pregnancy and delivery in a patient with 17,20-lyase deficiency. DESIGN: Controlled ovarian stimulation (COS) and In Vitro fertilization (IVF), cryopreservation of embryos and frozen-thawed embryo transfer (ET). SETTING: IVF clinic. PATIENT: A 24 years old, infertile patient with 17,20-lase deficiency. INTERVENTIONS: Controlled ovarian stimulation, follicular aspiration- egg retrieval, IVF, embryo cryopreservation, thawed ET...
April 7, 2021: Journal of Clinical Endocrinology and Metabolism
https://read.qxmd.com/read/33822983/letter-to-the-editor-from-alexis-m-mckee-glycemic-control-and-variability-of-diabetes-secondary-to-total-pancreatectomy-assessed-by-continuous-glucose-monitoring
#16
Alexis M McKee, Janet B McGill
No abstract text is available yet for this article.
April 5, 2021: Journal of Clinical Endocrinology and Metabolism
https://read.qxmd.com/read/33822975/response-to-letter-to-the-editor-from-mckee-and-mcgill-glycemic-control-and-variability-of-diabetes-secondary-to-total-pancreatectomy-assessed-by-continuous-glucose-monitoring
#17
Caroline T B Juel, Thomas F Dejgaard, Carsten P Hansen, Jan H Storkholm, Tina Vilsbøll, Asger Lund, Filip K Knop
No abstract text is available yet for this article.
April 5, 2021: Journal of Clinical Endocrinology and Metabolism
https://read.qxmd.com/read/33822973/response-to-letter-to-the-editor-from-h%C3%A3-l%C3%A3-ne-lasolle-usp8-and-tp53-drivers-are-associated-with-cnv-in-a-corticotroph-adenoma-cohort-enriched-for-aggressive-tumors
#18
Andrew V Uzilov, Eliza B Geer
No abstract text is available yet for this article.
April 5, 2021: Journal of Clinical Endocrinology and Metabolism
https://read.qxmd.com/read/33822969/plasma-cortisol-and-risk-of-atrial-fibrillation-a-mendelian-randomization-study
#19
Susanna C Larsson, Wei-Hsuan Lee, Stephen Burgess, Elias Allara
CONTEXT: Atrial fibrillation (AF), cardiac arrhythmias and related risk factors are common in patients with Cushing's syndrome, or clinical chronic hypercortisolism. While hypercortisolism may be associated with AF, this association has not yet been ascertained causally. OBJECTIVE: To determine whether plasma cortisol is causally associated with AF using a two-sample Mendelian randomization (MR) design. METHODS: Three genetic variants in the SERPINA1/SERPINA6 locus and functionally associated with plasma cortisol were identified in the CORtisol NETwork consortium (12 597 participants)...
April 5, 2021: Journal of Clinical Endocrinology and Metabolism
https://read.qxmd.com/read/33822961/letter-to-the-editor-from-helene-lasolle-usp8-and-tp53-drivers-are-associated-with-cnv-in-a-corticotroph-adenoma-cohort-enriched-for-aggressive-tumors
#20
Hélène Lasolle, Gérald Raverot
No abstract text is available yet for this article.
April 5, 2021: Journal of Clinical Endocrinology and Metabolism
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