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Clinical Gastroenterology and Hepatology

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https://read.qxmd.com/read/31301452/ulcerative-colitis-and-crohn-s-disease-have-the-same-burden-and-goals-for-treatment
#1
REVIEW
Catherine Le Berre, Ashwin N Ananthakrishnan, Silvio Danese, Siddharth Singh, Laurent Peyrin-Biroulet
It is unclear whether ulcerative colitis (UC) is a progressive disease like Crohn's disease (CD). Patients with UC are often undertreated, because of the possibility of curative colectomy and the perception that the disease burden is lower than that of CD. We discuss findings from studies that aimed to determine whether UC and CD have the same disease burden and should be treated in the same intensive way. We discuss the similarities between CD and UC, including effects on quality of life, long-term complications, strictures, increased risk of cancer, pseudopolyps, functional abnormalities, and anorectal dysfunction...
July 10, 2019: Clinical Gastroenterology and Hepatology
https://read.qxmd.com/read/31301451/effects-of-fecal-microbiota-transplantation-with-oral-capsules-in-obese-patients
#2
Jessica R Allegretti, Zain Kassam, Benjamin H Mullish, Austin Chiang, Madeline Carrellas, Jonathan Hurtado, Julian R Marchesi, Julie A K McDonald, Alexandros Pechlivanis, Grace F Barker, Jesus Miguens Blanco, Isabel Garcia-Perez, Wing Fei Wong, Ylaine Gerardin, Michael Silverstein, Kevin Kennedy, Christopher Thompson
BACKGROUND & AIMS: Studies in mice have shown that the intestinal microbiota can contribute to obesity via the anorexigenic gut hormone glucagon-like peptide 1 (GLP1) and bile acids, which affect lipid metabolism. We performed a randomized, placebo-controlled pilot study of the effects of fecal microbiota transplantation (FMT) in obese, metabolically uncompromised patients. METHODS: We performed a double-blind study of 22 obese patients (body mass index [BMI] ≥ 35kg/m2 ) without a diagnosis of diabetes, non-alcoholic steatohepatitis, or metabolic syndrome...
July 10, 2019: Clinical Gastroenterology and Hepatology
https://read.qxmd.com/read/31301450/response
#3
LETTER
Dennis Yang, Peter V Draganov
No abstract text is available yet for this article.
July 10, 2019: Clinical Gastroenterology and Hepatology
https://read.qxmd.com/read/31279953/an-unexpected-case-of-right-iliac-fossa-pain-amyand-hernia
#4
Teo Qi Tian, Kam Juinn Huar, Tousif Kabir
No abstract text is available yet for this article.
July 4, 2019: Clinical Gastroenterology and Hepatology
https://read.qxmd.com/read/31279952/additional-intestinal-mucosal-biopsy-sampling-for-research-is-safe-during-pediatric-endoscopic-procedures
#5
Christopher J Moran, Julia Noreck, Harland S Winter, Emma X Li, Jeffrey A Biller, Esther J Israel, Jess L Kaplan
No abstract text is available yet for this article.
July 4, 2019: Clinical Gastroenterology and Hepatology
https://read.qxmd.com/read/31279951/do-alterations-in-bone-mineral-density-go-beyond-borders-in-adults-with-celiac-disease
#6
Gloria Galli, Edith Lahner, Bruno Annibale
No abstract text is available yet for this article.
July 4, 2019: Clinical Gastroenterology and Hepatology
https://read.qxmd.com/read/31279950/medical-professional-liability-in-gastroenterology-understanding-the-claims-landscape-and-proposed-mechanisms-for-reform
#7
Megan A Adams, John I Allen
No abstract text is available yet for this article.
July 4, 2019: Clinical Gastroenterology and Hepatology
https://read.qxmd.com/read/31279949/respectful-payer-provider-collaboration-can-achieve-the-best-in-value-based-care
#8
Lili Brillstein, Joel V Brill, Brian Currie
No abstract text is available yet for this article.
July 4, 2019: Clinical Gastroenterology and Hepatology
https://read.qxmd.com/read/31279948/response-to-value-of-vav3-methylation-in-stool-dna-might-be-restricted-to-non-thiopurine-treated-inflammatory-bowel-disease-patients-cgh-d-19-01071
#9
LETTER
John B Kisiel, Douglas W Mahoney, William R Taylor, Paquale Klepp
No abstract text is available yet for this article.
July 4, 2019: Clinical Gastroenterology and Hepatology
https://read.qxmd.com/read/31255807/combined-effects-of-alcohol-and-metabolic-disorders-in-patients-with-chronic-liver-disease
#10
Fredrik Åberg, Pauli Puukka, Veikko Salomaa, Satu Männistö, Annamari Lundqvist, Liisa Valsta, Markus Perola, Antti Jula, Martti Färkkilä
No abstract text is available yet for this article.
June 27, 2019: Clinical Gastroenterology and Hepatology
https://read.qxmd.com/read/31255806/perspectives-of-clinicians-in-the-united-states-and-europe-on-monitoring-levels-of-biologic-agents-in-patients-receiving-biologic-therapies-for-inflammatory-bowel-diseases
#11
EDITORIAL
Stephen B Hanauer, Stefan Schreiber
No abstract text is available yet for this article.
June 27, 2019: Clinical Gastroenterology and Hepatology
https://read.qxmd.com/read/31254675/patients-eligible-for-trials-of-microbe-based-therapeutics-do-not-represent-the-population-with-recurrent-clostridioides-difficile-infection
#12
Colleen R Kelly, Monika Fischer, Ari Grinspan, Jessica R Allegretti
BACKGROUND & AIMS: Although there are many industry-funded trials of microbe-based therapeutics for Clostridioides (formerly Clostridium) difficile infection (CDI), not all patients are eligible for these trials, due to their strict enrollment criteria. Furthermore, given the widespread availability of fecal microbiota transplantation (FMT) and overwhelming evidence to support its efficacy, patients might refuse enrollment in trials with a placebo group. We analyzed willingness and eligibility of patients with recurrent CDI to participate in randomized controlled trials of microbe-based therapeutic agents...
June 26, 2019: Clinical Gastroenterology and Hepatology
https://read.qxmd.com/read/31254674/monitoring-a-combination-of-calprotectin-and-infliximab-identifies-patients-with-mucosal-healing-of-crohn-s-disease
#13
LETTER
Erwin Dreesen, Ann Gils
No abstract text is available yet for this article.
June 26, 2019: Clinical Gastroenterology and Hepatology
https://read.qxmd.com/read/31254673/microscopic-colitis-is-characterized-by-intestinal-dysbiosis
#14
David M Morgan, Yueming Cao, Kaia Miller, Jessica McGoldrick, Danielle Bellavance, Samantha M Chin, Stefan Halvorsen, Benjamin Maxner, James M Richter, Slim Sassi, Kristin E Burke, Joseph C Yarze, Jonas F Ludvigsson, Kyle Staller, Daniel C Chung, Hamed Khalili
No abstract text is available yet for this article.
June 26, 2019: Clinical Gastroenterology and Hepatology
https://read.qxmd.com/read/31252194/reply
#15
LETTER
Hye Won Lee, Beom Kyung Kim
No abstract text is available yet for this article.
June 25, 2019: Clinical Gastroenterology and Hepatology
https://read.qxmd.com/read/31252193/among-patients-with-undetectable-hepatitis-b-surface-antigen-and-hepatocellular-carcinoma-a-high-proportion-has-integration-of-hbv-dna-into-hepatocyte-dna-and-no-cirrhosis
#16
Danny Ka-Ho Wong, Serene Ching Yan Cheng, Loey Lung-Yi Mak, Elvis Wai-Pan To, Regina Cheuk-Lam Lo, Tan-To Cheung, Wai-Kay Seto, James Fung, Kwan Man, Ching-Lung Lai, Man-Fung Yuen
BACKGROUND & AIMS: In some individuals with undetectable serum levels of hepatitis B surface antigen (HBsAg), hepatitis B virus (HBV) DNA can still be detected in serum or hepatocytes and HBV replicates at low levels-this is called occult HBV infection (OBI). OBI has been associated with increased risk of hepatocellular carcinoma (HCC). We investigated the incidence of OBI in patients with HCC and other liver diseases. We also investigated whether, in patients with OBI and HCC, HBV DNA has integrated into the DNA of hepatocytes...
June 25, 2019: Clinical Gastroenterology and Hepatology
https://read.qxmd.com/read/31252192/nine-taenia-saginata-inhabit-the-intestine-in-a-patient
#17
Dong Ling, Li Qingcui, Li Hailong
No abstract text is available yet for this article.
June 25, 2019: Clinical Gastroenterology and Hepatology
https://read.qxmd.com/read/31252191/progression-of-inflammatory-bowel-diseases-throughout-latin-america-and-the-caribbean-a-systematic-review
#18
Paulo Gustavo Kotze, Fox E Underwood, Aderson Omar Mourão Cintra Damião, Jose Geraldo P Ferraz, Rogerio Saad-Hossne, Martin Toro, Beatriz Iade, Francisco Bosques-Padilla, Fábio Vieira Teixeira, Fabian Juliao-Banos, Daniela Simian, Subrata Ghosh, Remo Panaccione, Siew C Ng, Gilaad G Kaplan
BACKGROUND & AIMS: The incidence of inflammatory bowel diseases (IBD) is increasing in Latin America. We performed a systematic review to identify clinical and epidemiologic features of IBD in Latin America (including Mexico, Central America, and South America) and the Caribbean. METHODS: We searched MEDLINE, EMBASE, and SciELO databases for clinical or epidemiologic studies of Crohn's disease (CD) or ulcerative colitis (UC) from Latin American and Caribbean countries and territories that reported incidence, prevalence, ratio of UC:CD, IBD phenotype, and treatment, through September 12, 2018...
June 25, 2019: Clinical Gastroenterology and Hepatology
https://read.qxmd.com/read/31252190/consumption-of-fish-and-long-chain-n-3-polyunsaturated-fatty-acids-is-associated-with-reduced-risk-of-colorectal-cancer-in-a-large-european-cohort
#19
Elom K Aglago, Inge Huybrechts, Neil Murphy, Corinne Casagrande, Genevieve Nicolas, Tobias Pischon, Veronika Fedirko, Gianluca Severi, Marie-Christine Boutron-Ruault, Agnès Fournier, Verena Katzke, Tilman Kühn, Anja Olsen, Anne Tjønneland, Christina C Dahm, Kim Overvad, Cristina Lasheras, Antonio Agudo, Maria-Jose Sánchez, Pilar Amiano, José Maria Huerta, Eva Ardanaz, Aurora Perez-Cornago, Antonia Trichopoulou, Anna Karakatsani, Georgia Martimianaki, Domenico Palli, Valeria Pala, Rosario Tumino, Alessio Naccarati, Salvatore Panico, Bas Bueno-de-Mesquita, Anne May, Jeroen W G Derksen, Sophie Hellstrand, Bodil Ohlsson, Maria Wennberg, Bethany Van Guelpen, Guri Skeie, Magritt Brustad, Elisabete Weiderpass, Amanda J Cross, Heather Ward, Elio Riboli, Teresa Norat, Veronique Chajes, Marc J Gunter
BACKGROUND & AIMS: There is an unclear association between intake of fish and long-chain n-3 polyunsaturated fatty acids (n-3 LC-PUFAs) and colorectal cancer (CRC). We examined the association between fish consumption, dietary and circulating levels of n-3 LC-PUFAs, and ratio of n-6:n-3 LC-PUFA with CRC using data from the European Prospective Investigation into Cancer and Nutrition (EPIC) cohort. METHODS: Dietary intake of fish (total, fatty/oily, lean/white) and n-3 LC-PUFA were estimated by food frequency questionnaires given to 521,324 participants in the EPIC study; among these, 6291 individuals developed CRC (median follow up, 14...
June 25, 2019: Clinical Gastroenterology and Hepatology
https://read.qxmd.com/read/31252189/daily-aspirin-use-reduces-risk-of-fibrosis-progression-in-patients-with-nonalcoholic-fatty-liver-disease-providing-new-uses-for-an-old-drug
#20
EDITORIAL
Eduardo Vilar-Gomez, Naga Chalasani
No abstract text is available yet for this article.
June 25, 2019: Clinical Gastroenterology and Hepatology
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