Carolina Victoria Cruz Junho, Mayra Trentin-Sonoda, Karine Panico, Raquel Silva Neres Dos Santos, Mariana Vieira Abrahão, Imara Caridad Stable Vernier, Cristina Ribas Fürstenau, Marcela Sorelli Carneiro-Ramos
Almost 200 years ago, the first evidence described by Robert Bright (1836) showed the strong interaction between the kidneys and heart and, since then, the scientific community has dedicated itself to better understanding the mechanisms involved in the kidney-heart relationship, known in recent decades as cardiorenal syndrome (CRS). This syndrome includes a wide clinical variety that affects the kidneys and heart, in an acute or chronic manner. Moreover, it is well established in the literature that the immune system, the sympathetic nervous system, the renin-angiotensin-aldosterone, and the oxidative stress actively play a strong role in the cellular and molecular processes present in CRS...
November 2022: Heart Failure Reviews