Paul E Verweij, Bart J A Rijnders, Roger J M Brüggemann, Elie Azoulay, Matteo Bassetti, Stijn Blot, Thierry Calandra, Cornelius J Clancy, Oliver A Cornely, Tom Chiller, Pieter Depuydt, Daniele Roberto Giacobbe, Nico A F Janssen, Bart-Jan Kullberg, Katrien Lagrou, Cornelia Lass-Flörl, Russell E Lewis, Peter Wei-Lun Liu, Olivier Lortholary, Johan Maertens, Ignacio Martin-Loeches, M Hong Nguyen, Thomas F Patterson, Thomas R Rogers, Jeroen A Schouten, Isabel Spriet, Lore Vanderbeke, Joost Wauters, Frank L van de Veerdonk
PURPOSE: Invasive pulmonary aspergillosis is increasingly reported in patients with influenza admitted to the intensive care unit (ICU). Classification of patients with influenza-associated pulmonary aspergillosis (IAPA) using the current definitions for invasive fungal diseases has proven difficult, and our aim was to develop case definitions for IAPA that can facilitate clinical studies. METHODS: A group of 29 international experts reviewed current insights into the epidemiology, diagnosis and management of IAPA and proposed a case definition of IAPA through a process of informal consensus...
August 2020: Intensive Care Medicine