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JOURNAL ARTICLE
Matteo Vatta
No abstract text is available yet for this article.
January 2016: Trends in Cardiovascular Medicine
#42
JOURNAL ARTICLE
Jan Mannsverk, Tom Wilsgaard, Ellisiv B Mathiesen, Maja-Lisa Løchen, Knut Rasmussen, Dag S Thelle, Inger Njølstad, Laila Arnesdatter Hopstock, Kaare Harald Bønaa
BACKGROUND: Few studies have used individual person data to study whether contemporary trends in the incidence of coronary heart disease are associated with changes in modifiable coronary risk factors. METHODS AND RESULTS: We identified 29 582 healthy men and women ≥25 years of age who participated in 3 population surveys conducted between 1994 and 2008 in Tromsø, Norway. Age- and sex-adjusted incidence rates were calculated for coronary heart disease overall, out-of-hospital sudden death, and hospitalized ST-segment-elevation and non-ST-segment-elevation myocardial infarction...
January 5, 2016: Circulation
#43
EDITORIAL
Vlado Perkovic, Anthony Rodgers
Blood pressure is a potent determinant of cardiovascular risk, but the most appropriate targets for blood-pressure lowering have long been debated. Observational studies with a low risk of confounding have shown a linear relationship between blood pressure and cardiovascular risk down to 115/75 mm..
November 26, 2015: New England Journal of Medicine
#44
JOURNAL ARTICLE
Ming Ding, Ambika Satija, Shilpa N Bhupathiraju, Yang Hu, Qi Sun, Jiali Han, Esther Lopez-Garcia, Walter Willett, Rob M van Dam, Frank B Hu
BACKGROUND: The association between consumption of caffeinated and decaffeinated coffee and risk of mortality remains inconclusive. METHODS AND RESULTS: We examined the associations of consumption of total, caffeinated, and decaffeinated coffee with risk of subsequent total and cause-specific mortality among 74,890 women in the Nurses' Health Study (NHS), 93,054 women in the Nurses' Health Study II, and 40,557 men in the Health Professionals Follow-up Study. Coffee consumption was assessed at baseline using a semiquantitative food frequency questionnaire...
December 15, 2015: Circulation
#45
MULTICENTER STUDY
Luisa Soares-Miranda, David S Siscovick, Bruce M Psaty, W T Longstreth, Dariush Mozaffarian
BACKGROUND: Although guidelines suggest that older adults engage in regular physical activity (PA) to reduce cardiovascular disease (CVD), surprisingly few studies have evaluated this relationship, especially in those >75 years. In addition, with advancing age the ability to perform some types of PA might decrease, making light-moderate exercise such as walking especially important to meet recommendations. METHODS AND RESULTS: Prospective cohort analysis among 4207 US men and women of a mean age of 73 years (standard deviation=6) who were free of CVD at baseline in the Cardiovascular Health Study were followed from 1989 to 1999...
January 12, 2016: Circulation
#46
JOURNAL ARTICLE
Jack A Schalken, Gemma Westcott
No abstract text is available yet for this article.
2015: Future Oncology
#47
JOURNAL ARTICLE
Joshua C Bis, Colleen Sitlani, Ryan Irvin, Christy L Avery, Albert Vernon Smith, Fangui Sun, Daniel S Evans, Solomon K Musani, Xiaohui Li, Stella Trompet, Bouwe P Krijthe, Tamara B Harris, P Miguel Quibrera, Jennifer A Brody, Serkalem Demissie, Barry R Davis, Kerri L Wiggins, Gregory J Tranah, Leslie A Lange, Nona Sotoodehnia, David J Stott, Oscar H Franco, Lenore J Launer, Til Stürmer, Kent D Taylor, L Adrienne Cupples, John H Eckfeldt, Nicholas L Smith, Yongmei Liu, James G Wilson, Susan R Heckbert, Brendan M Buckley, M Arfan Ikram, Eric Boerwinkle, Yii-Der Ida Chen, Anton J M de Craen, Andre G Uitterlinden, Jerome I Rotter, Ian Ford, Albert Hofman, Naveed Sattar, P Eline Slagboom, Rudi G J Westendorp, Vilmundur Gudnason, Ramachandran S Vasan, Thomas Lumley, Steven R Cummings, Herman A Taylor, Wendy Post, J Wouter Jukema, Bruno H Stricker, Eric A Whitsel, Bruce M Psaty, Donna Arnett
BACKGROUND: Hypertension is a major risk factor for a spectrum of cardiovascular diseases (CVD), including myocardial infarction, sudden death, and stroke. In the US, over 65 million people have high blood pressure and a large proportion of these individuals are prescribed antihypertensive medications. Although large long-term clinical trials conducted in the last several decades have identified a number of effective antihypertensive treatments that reduce the risk of future clinical complications, responses to therapy and protection from cardiovascular events vary among individuals...
2015: PloS One
#48
EDITORIAL
Aiden Abidov
No abstract text is available yet for this article.
December 2016: Journal of Nuclear Cardiology
#49
JOURNAL ARTICLE
Salim S Virani, Thomas M Maddox, Paul S Chan, Fengming Tang, Julia M Akeroyd, Samantha A Risch, William J Oetgen, Anita Deswal, Biykem Bozkurt, Christie M Ballantyne, Laura A Petersen
BACKGROUND: The current number of physicians will not be sufficient to accommodate 30 to 40 million Americans expected to secure health coverage with Affordable Care Act implementation. One proposed solution is to use advanced practice providers (APPs) (nurse practitioners and physician assistants). OBJECTIVES: This study sought to determine whether there were clinically meaningful differences in the quality of care delivered by APPs versus physicians in a national sample of cardiology practices...
October 20, 2015: Journal of the American College of Cardiology
#50
REVIEW
Huseyin Naci, John P A Ioannidis
OBJECTIVE: To determine the comparative effectiveness of exercise versus drug interventions on mortality outcomes. DESIGN: Metaepidemiological study. ELIGIBILITY CRITERIA: Meta-analyses of randomised controlled trials with mortality outcomes comparing the effectiveness of exercise and drug interventions with each other or with control (placebo or usual care). DATA SOURCES: Medline and Cochrane Database of Systematic Reviews, May 2013...
November 2015: British Journal of Sports Medicine
#51
COMPARATIVE STUDY
Benjamin Z Galper, Y Claire Wang, Andrew J Einstein
BACKGROUND: Several approaches have been proposed for risk-stratification and primary prevention of coronary heart disease (CHD), but their comparative and cost-effectiveness is unknown. METHODS: We constructed a state-transition microsimulation model to compare multiple approaches to the primary prevention of CHD in a simulated cohort of men aged 45-75 and women 55-75. Risk-stratification strategies included the 2013 American College of Cardiology/American Heart Association (ACC/AHA) guidelines on the treatment of blood cholesterol, the Adult Treatment Panel (ATP) III guidelines, and approaches based on coronary artery calcium (CAC) scoring and C-reactive protein (CRP)...
2015: PloS One
#52
EDITORIAL
Lee Hooper, Nicole Martin, Asmaa Abdelhamid
No abstract text is available yet for this article.
December 2015: Heart
#53
REVIEW
Ahmed Hassaan Qavi, Rida Kamal, Robert W Schrier
Diuretics play significant role in pharmacology and treatment options in medicine. This paper aims to review and evaluate the clinical use of diuretics in conditions that lead to fluid overload in the body such as cardiac failure, cirrhosis, and nephrotic syndrome. To know the principles of treatment it is essential to understand the underlying pathophysiological mechanisms that cause the need of diuresis in the human body. Various classes of diuretics exist, each having a unique mode of action. A systemic approach for management is recommended based on the current guidelines, starting from thiazides and proceeding to loop diuretics...
2015: International Journal of Nephrology
#54
RANDOMIZED CONTROLLED TRIAL
Clara K Chow, Julie Redfern, Graham S Hillis, Jay Thakkar, Karla Santo, Maree L Hackett, Stephen Jan, Nicholas Graves, Laura de Keizer, Tony Barry, Severine Bompoint, Sandrine Stepien, Robyn Whittaker, Anthony Rodgers, Aravinda Thiagalingam
IMPORTANCE: Cardiovascular disease prevention, including lifestyle modification, is important but underutilized. Mobile health strategies could address this gap but lack evidence of therapeutic benefit. OBJECTIVE: To examine the effect of a lifestyle-focused semipersonalized support program delivered by mobile phone text message on cardiovascular risk factors. DESIGN AND SETTING: The Tobacco, Exercise and Diet Messages (TEXT ME) trial was a parallel-group, single-blind, randomized clinical trial that recruited 710 patients (mean age, 58 [SD, 9...
September 22, 2015: JAMA
#55
RANDOMIZED CONTROLLED TRIAL
Iftikhar J Kullo, Hayan Jouni, Janet E Olson, Victor M Montori, Kent R Bailey
BACKGROUND: Whether disclosure of a genetic risk score (GRS) for a common disease influences relevant clinical outcomes is unknown. We describe design of the Myocardial Infarction Genes (MI-GENES) Study, a randomized clinical trial to assess whether disclosing a GRS for coronary heart disease (CHD) leads to lowering of low-density lipoprotein cholesterol (LDL-C) levels. METHODS AND DESIGN: We performed an initial screening genotyping of 28 CHD susceptibility single-nucleotide polymorphisms (SNPs) that are not associated with blood pressure or lipid levels, in 1000 individuals from Olmsted County, Minnesota who were participants in the Mayo Clinic BioBank and met eligibility criteria...
August 15, 2015: BMC Medical Genomics
#56
RANDOMIZED CONTROLLED TRIAL
M C Koppelman, B L Parry, J A Hamilton, S W Alagna, D L Loriaux
Six women with primary hyperprolactinemia (mean prolactin level, 50 ng/ml) were matched with six normal women on eight factors influencing life style. Observers blind to endocrine status followed the subjects weekly for 10 weeks. Patients took bromocriptine, 2.5 mg twice daily, or placebo in a randomized double-blind sequence with crossover at 5 weeks. The mean Hamilton score for the patients was compatible with mild depression and higher than that for normal subjects during placebo but not during bromocriptine treatment...
August 1987: American Journal of Psychiatry
#57
REVIEW
C R Emerson
Low libido is the most frequently reported sexual dysfunction. This is an important and complex problem with multiple causes. At present the interpretation of data on this topic remains a challenge, as the subject population is diverse and various tools are used in assessment. Coupled with this, several definitions are in use with differing emphasis on distress resulting from this state. Developments in the understanding of psychopharmacology are shedding light on the pathways involved in normal sexual response and these are being utilized in the development of treatments...
May 2010: International Journal of STD & AIDS
#58
JOURNAL ARTICLE
Paolo Piaggi, Marie S Thearle, Jonathan Krakoff, Susanne B Votruba
CONTEXT: Body fat-free mass (FFM), energy expenditure (EE), and respiratory quotient (RQ) are known predictors of daily food intake. Because FFM largely determines EE, it is unclear whether body composition per se or the underlying metabolism drives dietary intake. OBJECTIVE: The objective of the study was to test whether 24-hour measures of EE and RQ and their components influence ad libitum food intake independently of FFM. DESIGN AND PARTICIPANTS: One hundred seven healthy individuals (62 males/45 females, 84 Native Americans/23 whites; age 33 ± 8 y; body mass index 33 ± 8 kg/m(2); body fat 31% ± 8%) had 24-hour measures of EE in a whole-room indirect calorimeter during energy balance, followed by 3 days of ad libitum food intake using computerized vending machine systems...
August 2015: Journal of Clinical Endocrinology and Metabolism
#59
EDITORIAL
Pradeep Bhambhvani
No abstract text is available yet for this article.
December 2016: Journal of Nuclear Cardiology
#60
JOURNAL ARTICLE
Gisela Teixido-Tura, Andre L C Almeida, Eui-Young Choi, Ola Gjesdal, David R Jacobs, Harry C Dietz, Kiang Liu, Stephen Sidney, Cora E Lewis, David Garcia-Dorado, Artur Evangelista, Samuel Gidding, João A C Lima
Aortic size increases with age, but factors related to such dilatation in healthy young adult population have not been studied. We aim to evaluate changes in aortic dimensions and its principal correlates among young adults over a 20-year time period. Reference values for aortic dimensions in young adults by echocardiography are also provided. Healthy Coronary Artery Risk Development in Young Adults (CARDIA) study participants aged 23 to 35 years in 1990-1991 (n=3051) were included after excluding 18 individuals with significant valvular dysfunction...
July 2015: Hypertension
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