collection
https://read.qxmd.com/read/33588249/assessment-of-benzodiazepine-dosing-strategies-for-the-management-of-status-epilepticus-in-the-emergency-department
#1
Kyle A Weant, Stephanie L Barré, Sara Bruner, Ryan Smiley, Gregory A Hall
PURPOSE: Although guidelines recommend specific benzodiazepine doses for the treatment of generalized convulsive status epilepticus (GCSE), underdosing appears to be common. The purpose of this investigation was to assess benzodiazepine dosing strategies for the initial management of GCSE in patients presenting to the Emergency Department (ED). METHODS: This was a retrospective review of adult patients who received benzodiazepines in the ED for treatment of GCSE...
February 6, 2021: American Journal of Emergency Medicine
https://read.qxmd.com/read/30912825/emergency-medical-services-protocols-for-generalized-convulsive-status-epilepticus
#2
John P Betjemann, S Andrew Josephson, Daniel H Lowenstein, Elan L Guterman
No abstract text is available yet for this article.
March 26, 2019: JAMA
https://read.qxmd.com/read/26900382/evidence-based-guideline-treatment-of-convulsive-status-epilepticus-in-children-and-adults-report-of-the-guideline-committee-of-the-american-epilepsy-society
#3
Tracy Glauser, Shlomo Shinnar, David Gloss, Brian Alldredge, Ravindra Arya, Jacquelyn Bainbridge, Mary Bare, Thomas Bleck, W Edwin Dodson, Lisa Garrity, Andy Jagoda, Daniel Lowenstein, John Pellock, James Riviello, Edward Sloan, David M Treiman
CONTEXT: The optimal pharmacologic treatment for early convulsive status epilepticus is unclear. OBJECTIVE: To analyze efficacy, tolerability and safety data for anticonvulsant treatment of children and adults with convulsive status epilepticus and use this analysis to develop an evidence-based treatment algorithm. DATA SOURCES: Structured literature review using MEDLINE, Embase, Current Contents, and Cochrane library supplemented with article reference lists...
January 2016: Epilepsy Currents
https://read.qxmd.com/read/22528274/guidelines-for-the-evaluation-and-management-of-status-epilepticus
#4
Gretchen M Brophy, Rodney Bell, Jan Claassen, Brian Alldredge, Thomas P Bleck, Tracy Glauser, Suzette M Laroche, James J Riviello, Lori Shutter, Michael R Sperling, David M Treiman, Paul M Vespa
Status epilepticus (SE) treatment strategies vary substantially from one institution to another due to the lack of data to support one treatment over another. To provide guidance for the acute treatment of SE in critically ill patients, the Neurocritical Care Society organized a writing committee to evaluate the literature and develop an evidence-based and expert consensus practice guideline. Literature searches were conducted using PubMed and studies meeting the criteria established by the writing committee were evaluated...
August 2012: Neurocritical Care
https://read.qxmd.com/read/11547716/a-comparison-of-lorazepam-diazepam-and-placebo-for-the-treatment-of-out-of-hospital-status-epilepticus
#5
RANDOMIZED CONTROLLED TRIAL
B K Alldredge, A M Gelb, S M Isaacs, M D Corry, F Allen, S Ulrich, M D Gottwald, N O'Neil, J M Neuhaus, M R Segal, D H Lowenstein
BACKGROUND: It is uncertain whether the administration of benzodiazepines by paramedics is an effective and safe treatment for out-of-hospital status epilepticus. METHODS: We conducted a randomized, double-blind trial to evaluate intravenous benzodiazepines administered by paramedics for the treatment of out-of-hospital status epilepticus. Adults with prolonged (lasting five minutes or more) or repetitive generalized convulsive seizures received intravenous diazepam (5 mg), lorazepam (2 mg), or placebo...
August 30, 2001: New England Journal of Medicine
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