[Effects of preoxygenation methods on the course of PaO2 and PaCO2 in anesthetic post-induction apnea]

O Fleureaux, J P Estèbe, C Bléry, N Douet, Y Mallédant
Cahiers D'anesthésiologie 1995, 43 (4): 367-70
This study compares two preoxygenation techniques by blood gases measurements during induction of anaesthesia. After hospital ethics committee approval, 17 adult surgical patients, ASA I, all free of cardiac or lung disease were randomly assigned to two groups. Before preoxygenation, venous and radial artery canulations were performed. The patients were not premedicated and rested supine. Oxygen was given using a Mapleson A system with a 10 l.min-1 flow. In group I, 9 patients breathed 100 per cent O2 with a normal pattern. In group II, 8 patients took four deep breaths of 100 per cent O2 within 30 seconds. After this, the mask was removed and anaesthesia was induced with thiopental (5, phenoperidine (0.04 and vecuronium (0.1 After intubation, patients remained apnoeic until SpO2 decreased to 90%. Samples for arterial blood gas measurements were obtained before preoxygenation and then every minute. The two groups were similar in age (26.8 +/- 8.1 vs 29.2 +/- 9.0 years) and weight. The group I had significantly higher PaO2 immediately after preoxygenation (397 +/- 49 vs 293 +/- 86 mmHg) and the time for SaO2 to decrease to 95% was significantly shorter in group II (3 +/- 1 vs 1.87 +/- 0.99 min). PaCO2 was not different after preoxygenation in group II. In summary, healthy and young patients receive better protection against hypoxia with normal breathing of 100% for 4 minutes.

Full Text Links

Find Full Text Links for this Article


You are not logged in. Sign Up or Log In to join the discussion.

Related Papers

Remove bar
Read by QxMD icon Read

Save your favorite articles in one place with a free QxMD account.


Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"