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Acquired myelinated retinal nerve fiber layer in a child with neurofibromatosis 1-related optic pathway glioma.
Journal of AAPOS : the Official Publication of the American Association for Pediatric Ophthalmology and Strabismus 2024 Februrary 14
Myelinated retinal nerve fiber layer (RNFL) is a rare structural anomaly that occurs from abnormal myelination extending anterior to the lamina cribrosa. Clinically, myelinated RNFL is characterized as a gray-white lesion with feathered, well-demarcated borders obscuring the retinal vasculature. Myelinated RNFL is typically congenital, benign, and asymptomatic. It is most commonly noted as an incidental finding on ophthalmic examination. However, cases of acquired myelinated RNFL have been reported. We report the case of a patient with neurofibromatosis type 1 and optic pathway glioma with unilateral acquired myelinated RNFL.
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