A fatal septic shock caused by Capnocytophaga gingivalis potentially associated with COVID-19: A case report.

BACKGROUND: Capnocytophaga spp. is associated with fulminant sepsis, particularly in those with immunosuppression. We here report a rare case of fatal fulminant septic shock caused by C. gingivalis , concurrent with COVID-19.

CASE PRESENTATION: A Japanese woman developed septic shock, which led to her death. Polymerase chain reaction (PCR) testing of the respiratory specimen was positive for SARS-CoV-2, and a CT scan of the chests revealed bilateral ground glass opacities. The blood cultures identified C. gingivalis . The patient had rheumatoid arthritis and was taking prednisone orally. There were no splenic abnormalities shown on the CT scan.

CONCLUSION: A rare case of fulminant septic shock caused by C. gingivalis , together with COVID-19 was identified. The precise pathogenesis of this combination, together with the best treatment option should be sought by further studies.