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Adhesion of Methicillin-Resistant Staphylococcus aureus and Candida albicans to Parylene-C-Coated Polymethyl Methacrylate.

PURPOSE: To determine whether coating polymethyl methacrylate (PMMA) discs with Parylene-C would reduce Staphylococcus aureus and Candida albicans biofilm formation.

MATERIALS AND METHODS: MRSA and Candida albicans single and dual biofilms were grown for 48 hours in artificial saliva on parylene-C-coated or uncoated PMMA, and the viable biofilm colony-forming units were counted.

RESULTS: There was no significant difference in the count of viable methicillin-resistant Staphylococcus aureus or Candida albicans recovered from single- or dual-species biofilms between coated and uncoated PMMA discs.

CONCLUSION: Parylene-C does not prevent biofilm formation on PMMA.

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