We have located links that may give you full text access.
The Wolff-Rearrangement Reaction of Oxidatively Generated α-Oxo Gold Carbenes: An Effective Approach to Silylketenes.
Angewandte Chemie 2019 Februrary 21
Gold-catalyzed oxidations of alkynes by N-oxides offer a direct access to reactive α-oxo gold carbene intermediates from benign and readily available alkynes instead of hazardous diazo carbonyl compounds. Despite various versatile synthetic methods developed based on this strategy, one of the hallmarks of α-oxo carbene/carbenoid chemistry, i.e., the Wolff rearrangement, has not been realized in this context. This study discloses the first examples that the Wolff rearrangement can be readily realized by α-oxo gold carbenes oxidatively generated from TBS-terminated alkynes. The thus-generated silylketenes can be isolated pure or subsequently trapped by various internal or external nucleophiles in one pot to afford α-silylated carboxylic acids, their derivatives or TBS-substituted allenes.
Full text links
Related Resources
Get seemless 1-tap access through your institution/university
For the best experience, use the Read mobile app
All material on this website is protected by copyright, Copyright © 1994-2024 by WebMD LLC.
This website also contains material copyrighted by 3rd parties.
By using this service, you agree to our terms of use and privacy policy.
Your Privacy Choices
You can now claim free CME credits for this literature searchClaim now
Get seemless 1-tap access through your institution/university
For the best experience, use the Read mobile app