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Competition for Food Drives Stem Cell Fate in Facultative Niches.

Maëlle Givelet, Clémentine Lapoujade, Pierre Fouchet
Cell Stem Cell 2019 January 4
Mechanisms regulating maintenance of the stem cell pool in facultative niches of the mammalian testis are poorly understood. In this issue of Cell Stem Cell, Kitadate et al. (2019) propose a minimal model in which stem cells compete for limited resources of fibroblast growth factors, which predicts their density during homeostasis and regenerative conditions.

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