Leaping Together Toward Sustainable, Patient-Centered Innovation: The Value of a Multistakeholder Safe Haven for Accelerating System Change.

Successfully delivering on the promise of emerging science in a world of value-driven healthcare requires that we fundamentally reengineer biomedical innovation processes to be both patient centered and sustainable. Massachusetts Institute of Technology's New Drug Development Paradigms (NEWDIGS), a "think and do" tank launched in 2010, provides a safe haven, precompetitive environment for multistakeholder collaboration to innovate how we innovate. Its newest project, Learning Ecosystems Accelerator for Patient-centered, Sustainable innovation (LEAPS), will pilot an innovation system designed to enhance decision making, outcomes, and trust among key stakeholders.