JOURNAL ARTICLE

A toxic epidermal necrolysis-like presentation of linear IgA bullous dermatosis treated with dapsone

Julie K Nguyen, Misha V Koshelev, Bartley J Gill, Jessica Boulavsky, Abdul Hafeez Diwan, Harry Dao
Dermatology Online Journal 2017 August 15, 23 (8)
29469740
Linear IgA bullous dermatosis is a rare autoimmune vesiculobullous disease characterized by linear deposition of IgA along the basement membrane zone. It is classically idiopathic, but may also arise secondary to drug exposure. A heterogeneous spectrum of clinical features has been described, including a rare, morbid variant mimicking toxic epidermal necrolysis. Herein, we present a case of vancomycin-induced linear IgA bullous dermatosis that manifested clinically as toxic epidermal necrolysis and resolved with dapsone therapy.

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