KMgene: a unified R package for gene-based association analysis for complex traits.

Summary: In this report, we introduce an R package KMgene for performing gene-based association tests for familial, multivariate or longitudinal traits using kernel machine (KM) regression under a generalized linear mixed model framework. Extensive simulations were performed to evaluate the validity of the approaches implemented in KMgene.

Availability and implementation: https://cran.r-project.org/web/packages/KMgene.

Supplementary information: Supplementary data are available at Bioinformatics online.