Is pulsed ultrasound an alternative for osteoarthritis?

INTRODUCTION: Many osteoarthritis patients persist symptomatic despite nonsurgical treatment. Pulsed ultrasound might be a viable alternative for such cases, but its real clinical relevance remains unclear.

METHODS: A literature review was conducted in Epistemonikos, the largest database for sys-tematic reviews in health that compiles multiple sources, including MEDLINE, EMBASE, and Cochrane, among others. Relevant data were extracted, and infor-mation from the primary studies was reanalyzed. A subsequent meta-analysis was conducted, and summary of findings tables were constructed using the GRADE methodology.

RESULTS AND CONCLUSIONS: Six systematic reviews including eight randomized trials were identified. In conclusion, it is not clear whether pulsed ultrasound improves functionality, and it might slightly decrease pain but the certainty of the evidence is low.