JOURNAL ARTICLE

Clinical and molecular epidemiology of Escherichia coli sequence type 131 among hospitalized patients colonized intestinally with fluoroquinolone-resistant E. coli

Jennifer H Han, Brian Johnston, Irving Nachamkin, Pam Tolomeo, Warren B Bilker, Xiangqun Mao, Connie Clabots, Ebbing Lautenbach, James R Johnson
Antimicrobial Agents and Chemotherapy 2014, 58 (11): 7003-6
25199782
This study examined molecular and epidemiologic factors associated with Escherichia coli sequence type 131 (ST131) among hospitalized patients colonized intestinally with fluoroquinolone (FQ)-resistant E. coli between 2002 and 2004. Among 86 patients, 21 (24%) were colonized with ST131. The proportion of ST131 isolates among colonizing isolates increased significantly over time, from 8% in 2002 to 50% in 2004 (P = 0.003). Furthermore, all 19 clonally related isolates were ST131. Future studies should identify potential transmissibility differences between ST131 and non-ST131 strains.

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