[Effects of drugs for lifestyle-related diseases on bone metabolism].

Accumulating evidence indicates several drugs for lifestyle-related diseases are involved in bone metabolism. Drugs that might reduce fracture incidence are statins, β-blockers and thiazide diuretics, and those that might increase fractures are thiazolidinediones and loop diuretics. It is yet controversial whether ACE inhibitors, angiotensin receptor- II blockers and aldosterone receptor antagonists are indeed involved in the increase or the decrease in fracture incidence.