We have located links that may give you full text access.
English Abstract
Journal Article
[In vitro susceptibility to linezolid in methicillin-resistant Staphylococcus aureus and vancomycin-resistant Enterococcus strains].
Mikrobiyoloji Bülteni 2009 October
There has been a dramatic increase in the number of infections caused by methicillin-resistant Staphylococcus aureus (MRSA) and vancomycin-resistant enterococci (VRE) worldwide. Linezolid which is one of the first oxazolidinones in clinical use, has bacteriostatic activity on gram-positive bacteria including MRSA and VRE. The aim of this study was to investigate the in vitro susceptibilities of MRSA and VRE clinical isolates to linezolid. A total of 100 MRSA strains isolated from clinical specimens as infectious agents (96 blood, 2 pleural fluid, 1 peritoneal fluid, 1 joint fluid isolates), and 101 VRE (Enterococcus faecium) strains isolated from clinical specimens as colonizing or infectious agents (79 rectal swabs, 11 blood, 3 catheter, 3 peritoneal fluid, 3 urine, 2 wound isolates) in Microbiology Laboratory of Uludag University Medical Faculty Hospital, Turkey, were included to the study. In vitro linezolid activity has been searched by E-test method and all of the isolates were found susceptible to linezolid. Linezolid minimal inhibitory concentration (MIC) ranged for MRSA and VRE between 0.25-3 microg/mL and 0.25-2 microg/mL, respectively. Linezolid MIC50 and MIC90 values for MRSA were 1.5 microg/mL and 2 microg/mL, respectively, while for VRE these values were 0.75 microg/mL and 1.5 microg/mL, respectively. Our results were in parallel with the data of other national and international studies, emphasizing that linezolid is a new and effective choice in treatment of infections caused by resistant gram-positive bacteria.
Full text links
Related Resources
Get seemless 1-tap access through your institution/university
For the best experience, use the Read mobile app
All material on this website is protected by copyright, Copyright © 1994-2024 by WebMD LLC.
This website also contains material copyrighted by 3rd parties.
By using this service, you agree to our terms of use and privacy policy.
Your Privacy Choices
You can now claim free CME credits for this literature searchClaim now
Get seemless 1-tap access through your institution/university
For the best experience, use the Read mobile app