We have located links that may give you full text access.
Journal Article
Research Support, Non-U.S. Gov't
[Interfractional and intrafractional setup errors in radiotherapy for tumors analyzed by cone-beam computed tomography].
Ai Zheng = Aizheng = Chinese Journal of Cancer 2008 October
BACKGROUND & OBJECTIVE: Both interfractional and intrafractional setup errors may affect the precision of radiotherapy. This study was to analyze the interfractional and intrafractional setup errors in radiotherapy for tumors using cone-beam computed tomography(CBCT).
METHODS: Of the 51 patients received radiotherapy, 19 had head and neck tumors, 25 had thoracic tumors, and seven had abdominal-pelvic tumors. Patients received CBCT scans after initial setup, after re-positioning and after radiation delivery. The CBCT images were registered to the planning CT images, and setup errors on X,Y, Z axes were analyzed.
RESULTS: A total of 1,934 CBCT scans were performed on 51 patients, of which 955 were performed after initial setup, 525 after re-positioning and 454 after radiation delivery. The interfractional setup errors on X, Y and Z axes were (1.2+/-0.9) mm,(1.2+/-1.1) mm and (1.0+/-0.8) mm, respectively, for head and neck tumors; (2.3+/-1.9) mm, (4.2+/-3.7) mm and (2.4+/-2.1) mm, respectively, for thoracic tumors; (1.7+/-1.5) mm,(4.7+/-3.6) mm and (2.1+/-1.6) mm, respectively, for abdominal-pelvic tumors. Comparing with the post-correction position, the post-treatment setup errors in head and neck tumors increased significantly on all three axes (P < 0.05), whereas the difference was not significant in trunk tumors (P > 0.05).
CONCLUSIONS: Measurement and correction of interfractional setup errors before each fraction using CBCT could help to improve the precision of radiotherapy. The intrafractional setup error variations are obvious in head and neck tumors and should be taken into account during treatment planning. The intrafractional setup errors in trunk tumors need further study.
METHODS: Of the 51 patients received radiotherapy, 19 had head and neck tumors, 25 had thoracic tumors, and seven had abdominal-pelvic tumors. Patients received CBCT scans after initial setup, after re-positioning and after radiation delivery. The CBCT images were registered to the planning CT images, and setup errors on X,Y, Z axes were analyzed.
RESULTS: A total of 1,934 CBCT scans were performed on 51 patients, of which 955 were performed after initial setup, 525 after re-positioning and 454 after radiation delivery. The interfractional setup errors on X, Y and Z axes were (1.2+/-0.9) mm,(1.2+/-1.1) mm and (1.0+/-0.8) mm, respectively, for head and neck tumors; (2.3+/-1.9) mm, (4.2+/-3.7) mm and (2.4+/-2.1) mm, respectively, for thoracic tumors; (1.7+/-1.5) mm,(4.7+/-3.6) mm and (2.1+/-1.6) mm, respectively, for abdominal-pelvic tumors. Comparing with the post-correction position, the post-treatment setup errors in head and neck tumors increased significantly on all three axes (P < 0.05), whereas the difference was not significant in trunk tumors (P > 0.05).
CONCLUSIONS: Measurement and correction of interfractional setup errors before each fraction using CBCT could help to improve the precision of radiotherapy. The intrafractional setup error variations are obvious in head and neck tumors and should be taken into account during treatment planning. The intrafractional setup errors in trunk tumors need further study.
Full text links
Related Resources
Get seemless 1-tap access through your institution/university
For the best experience, use the Read mobile app
All material on this website is protected by copyright, Copyright © 1994-2024 by WebMD LLC.
This website also contains material copyrighted by 3rd parties.
By using this service, you agree to our terms of use and privacy policy.
Your Privacy Choices
You can now claim free CME credits for this literature searchClaim now
Get seemless 1-tap access through your institution/university
For the best experience, use the Read mobile app