[Ambulatory anesthesia for an adult patient with autism and epilepsy: sedation using oral and intravenous dexmedetomidine].

A 22-year-old male patient with autism and epilepsy was scheduled to undergo impacted third molar extractions at an outpatient setting. Oral preanesthetic medication with dexmedetomidine and subsequent midazolam with ketamine was acceptable and effective to place intravenous cannula. General anesthesia was maintained with intravenous propofol and dexmedetomidine and operation was performed uneventfully. Sedation with intravenous dexmedetomidine was continued after operation to attenuate and/or manage postoperative problems, such as emergence agitation, dysphoric reactions, pain, opioid-related nausea/vomiting and seizure. He recovered from postoperative sedation and was discharged home without significant problems. Oral and intravenous dexmedetomidine was useful for anesthetic care in the uncooperative patient.