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Reactive oxygen species regulate autophagy through redox-sensitive proteases.
Developmental Cell 2007 April
Starvation induces autophagy through a signal transduction pathway that is not fully understood. In a recent issue of The EMBO Journal, Scherz-Shouval and colleagues (Scherz-Shouval et al., 2007) show that reactive oxygen species (ROS) occurring during starvation serve as signaling molecules that initiate autophagy.
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