We have located links that may give you full text access.
Interferon-gamma levels in familial Mediterranean fever.
Joint, Bone, Spine : Revue du Rhumatisme 2005 January
AIMS: To evaluate the levels of endogenous interferon-gamma (IFN-gamma) in patients with familial Mediterranean fever (FMF).
METHODS: Plasma levels of IFN-gamma were assayed in 29 FMF patients in attack-free period (mean age: 32, min-max: 17-48; male/female: 10/19), 18 FMF patients with acute FMF attack (mean age: 32, min-max: 19-50; male/female: 8/10), and 19 healthy controls (mean age: 31.94 +/- 1.50, min-max: 23-42; male/female: 11/8). IFN-gamma levels were also compared among colchicine treated and untreated groups.
RESULTS: Median plasma IFN-gamma levels were significantly higher in patients both with and without FMF attack than the control group (P < 0.05). Moreover, plasma IFN-gamma levels were higher in patients with acute FMF attack compared to patients in attack-free periods (P < 0.05). Plasma levels of IFN-gamma were comparable in colchicine treated and untreated groups.
CONCLUSION: Our results suggest that IFN-gamma may contribute to the inflammatory cascade of FMF.
METHODS: Plasma levels of IFN-gamma were assayed in 29 FMF patients in attack-free period (mean age: 32, min-max: 17-48; male/female: 10/19), 18 FMF patients with acute FMF attack (mean age: 32, min-max: 19-50; male/female: 8/10), and 19 healthy controls (mean age: 31.94 +/- 1.50, min-max: 23-42; male/female: 11/8). IFN-gamma levels were also compared among colchicine treated and untreated groups.
RESULTS: Median plasma IFN-gamma levels were significantly higher in patients both with and without FMF attack than the control group (P < 0.05). Moreover, plasma IFN-gamma levels were higher in patients with acute FMF attack compared to patients in attack-free periods (P < 0.05). Plasma levels of IFN-gamma were comparable in colchicine treated and untreated groups.
CONCLUSION: Our results suggest that IFN-gamma may contribute to the inflammatory cascade of FMF.
Full text links
Related Resources
Get seemless 1-tap access through your institution/university
For the best experience, use the Read mobile app
All material on this website is protected by copyright, Copyright © 1994-2024 by WebMD LLC.
This website also contains material copyrighted by 3rd parties.
By using this service, you agree to our terms of use and privacy policy.
Your Privacy Choices 
You can now claim free CME credits for this literature searchClaim now
Get seemless 1-tap access through your institution/university
For the best experience, use the Read mobile app