Use the keywords feature with a free QxMD account.
Use Read by QxMD to access full text via your institution or open access sources.
Read also provides personalized recommendations to keep you up to date in your field.
Existing User
Sign InNew to Read
Sign Up#1
RANDOMIZED CONTROLLED TRIAL
Ming Xu, Xu Zhang, Yue Zhuo, Wanrong Wu, Qiong Liu, Shuang Qin, Zhuan Long, Kun Ai, Ya Li, Hong Zhang
BACKGROUND: Urinary incontinence (UI) is a great problem of public health, especially for women's quality of life. UI afflicts at least 21.6% of the global population, and more than half of the UI is related to female stress urinary incontinence (SUI). Mawangdui Guidance plays an important role in preventing diseases and maintaining health. METHODS: Sixty female patients with SUI were randomly divided into a control group (n = 30) and an experimental group (n = 30)...
April 12, 2024: Medicine (Baltimore)
#2
REVIEW
Jacob D Bonadio, Ghazal Bashiri, Patrick Halligan, Michael Kegel, Fatima Ahmed, Karin Wang
Fibronectin (FN) is a critical component of extracellular matrix (ECM) contributing to various physiological processes, including tissue repair and immune response regulation. FN regulates various cellular functions such as adhesion, proliferation, migration, differentiation, and cytokine release. Alterations in FN expression, deposition, and molecular structure can profoundly impact its interaction with cells, growth factors, ECM components, and associated signaling pathways, thus influencing the progress of diseases such as fibrosis and autoimmune disorders...
April 6, 2024: Advanced Drug Delivery Reviews
#3
JOURNAL ARTICLE
Di An, Jianxia Wang, Fan Zhang, Huafang Jing, Yi Gao, Huiling Cong, Guodong Su, Miao Ye, Chunying Hu, Juan Wu, Limin Liao
BACKGROUND: Urinary incontinence symptoms severely affect older people with different body mass index (BMI).To compare the efficacy of the pelvic floor muscle training (PFMT) in patients with post-prostatectomy incontinence with different BMI. METHODS: Thirty-seven patients with post-prostatectomy incontinence were included. They were divided into group A (BMI ≤ 25,12), group B (26 ≤ BMI ≤ 30,14), and group C (BMI ≥ 31,11) based on difference BMI...
March 28, 2024: BMC Urology
#4
JOURNAL ARTICLE
Susan M Yount-Tavener, Rebecca A Fay
INTRODUCTION: To be effective, pelvic floor muscle therapy (PFMT) exercises should be intense, be practiced consistently, and include clinical support. Many women do not adhere to a consistent PFMT program, compromising the resolution or prevention of urinary incontinence (UI). This study aimed to answer 2 key questions: What prevents women from performing PFMT long term, and what can health care providers do to support women to perform them? METHODS: Postpartum women from 4 sites in the United States completed a questionnaire about experiences with PFMT or Kegel exercises during and after pregnancy...
March 23, 2024: Journal of Midwifery & Women's Health
#5
JOURNAL ARTICLE
Surahman Hakim, Budi Iman Santoso, Harrina Erlianti Rahardjo, Siti Setiati, Widjajalaksmi Kusumaningsih, Erwinanto, Joedo Prihartono, Nurhadi Ibrahim, Wresti Indriatmi
OBJECTIVE: Stress urinary incontinence (SUI) is a common problem that affects the quality of life of women worldwide. Pelvic floor muscle training (PFMT) is an effective conservative first-line treatment for SUI. However, low compliance with PFMT is one of the main reasons for therapeutic failure. Indirect supervision using a guidebook may improve PFMT outcomes. To develop a PFMT guidebook using the analyze, design, development, implementation, and evaluation (ADDIE) method. METHODS: A guidebook was developed from July 2020 to April 2021 using the ADDIE method...
March 13, 2024: Obstetrics & Gynecology Science
#6
JOURNAL ARTICLE
Nicola Clemente, Vipul D Yagnik, Pankaj Garg
No abstract text is available yet for this article.
March 13, 2024: Diseases of the Colon and Rectum
#7
JOURNAL ARTICLE
Yahong Xue, Shuqing Ding, Huifen Zhou, Min Li, Jianbao Cao, Qian Chen, Yijiang Ding
BACKGROUND/AIMS: Functional anorectal pain is one of several types of functional anorectal disorders. In this study, we compared the effectiveness of acupuncture (intervention) and biofeedback (control) as treatment for patients with functional anorectal pain. MATERIALS AND METHODS: This prospective, single-center, randomized, and comparative study examined 68 patients with functional anorectal pain who were recruited from June 2017 to January 2019 at the Nanjing Hospital of Chinese Medicine Affiliated to Nanjing University of Chinese Medicine...
February 2024: Turkish Journal of Gastroenterology: the Official Journal of Turkish Society of Gastroenterology
#8
JOURNAL ARTICLE
Jenea M Bin, Daumante Suminaite, Silvia K Benito-Kwiecinski, Linde Kegel, Maria Rubio-Brotons, Jason J Early, Daniel Soong, Matthew R Livesey, Richard J Poole, David A Lyons
Axon diameter influences the conduction properties of myelinated axons, both directly, and indirectly through effects on myelin. However, we have limited understanding of mechanisms controlling axon diameter growth in the central nervous system, preventing systematic dissection of how manipulating diameter affects myelination and conduction along individual axons. Here we establish zebrafish to study axon diameter. We find that importin 13b is required for axon diameter growth, but does not affect cell body size or axon length...
February 27, 2024: Nature Communications
#9
JOURNAL ARTICLE
Letícia Kegele Lignani, Raquel de Vasconcellos Carvalhaes de Oliveira, Eliane Matos Dos Santos, Luiz Antonio Bastos Camacho, Janaína Reis Xavier, Gloria Regina da Silva E Sá, Marilda Mendonça Siqueira, Andréa Marques Vieira da Silva, Juliana Gil Melgaço, Nathalia Dos Santos Alves, Maria de Lourdes de Sousa Maia, Enirtes Caetano Prates Melo
OBJECTIVE: Assess the level of measles vaccine-induced neutralizing antibodies against the D8 genotype and the persistence of humoral and cell-mediated immunity in children who received their first dose of the measles, mumps, and rubella vaccine eight years previously. METHODS: Measles-specific IgG and neutralizing antibodies were determined in serum using ELISA and plaque reduction neutralization test, respectively. Cellular response was evaluated from peripheral blood mononuclear cells (PBMC)...
February 26, 2024: Vaccine
#10
JOURNAL ARTICLE
Mingcai Dai, Manmo Bai, Yunqiang Chen, Juhui Li, Tian Wan, Huiyu Jiang
BACKGROUND: Pelvic congestion syndrome (PCS), also known as ovarian vein syndrome, is one of the key causes of chronic pelvic pain. The present study combined pelvic floor myofascial manipulation, uterine conditioning, and improved Kegel exercise for the treatment of a PCS patient with pelvic inclination to provide a reference for clinical therapy. CASE DESCRIPTION: A 29-year-old female was admitted to our hospital on 20th April 2023, with the main complaint being repeated lower abdominal and lumbosacral pain with frequent urination (urine volume < 200 ml/time), external genital itching accompanied by increased secretion for more than 5 years...
February 9, 2024: Alternative Therapies in Health and Medicine
#11
JOURNAL ARTICLE
Richard Drexler, Franz L Ricklefs, Sharona Ben-Haim, Anna Rada, Friedrich Wörmann, Thomas Cloppenborg, Christian G Bien, Matthias Simon, Thilo Kalbhenn, Albert Colon, Kim Rijkers, Olaf Schijns, Valeri Borger, Rainer Surges, Hartmut Vatter, Michele Rizzi, Marco de Curtis, Giuseppe Didato, Nicoló Castelli, Alexandre Carpentier, Bertrand Mathon, Clarissa Lin Yasuda, Fernando Cendes, Poodipedi Sarat Chandra, Manjari Tripathi, Hans Clusmann, Daniel Delev, Marc Guenot, Claire Haegelen, Hélène Catenoix, Johannes Lang, Hajo Hamer, Sebastian Brandner, Katrin Walther, Jason S Hauptmann, Rosalind L Jeffree, Josua Kegele, Eliane Weinbrenner, Georgios Naros, Julia Velz, Niklaus Krayenbühl, Julia Onken, Ulf C Schneider, Martin Holtkamp, Karl Rössler, Andrea Spyrantis, Adam Strzelczyk, Felix Rosenow, Stefan Stodieck, Mario A Alonso-Vanegas, Jörg Wellmer, Tim Wehner, Lasse Dührsen, Jens Gempt, Thomas Sauvigny
OBJECTIVE: Benchmarking has been proposed to reflect surgical quality and represents the highest standard reference values for desirable results. We sought to determine benchmark outcomes in patients after surgery for drug-resistant mesial temporal lobe epilepsy (MTLE). METHODS: This retrospective multicenter study included patients who underwent MTLE surgery at 19 expert centers on five continents. Benchmarks were defined for 15 endpoints covering surgery and epilepsy outcome at discharge, 1 year after surgery, and the last available follow-up...
February 24, 2024: Epilepsia
#12
JOURNAL ARTICLE
Nacc1 mutation in mice models rare neurodevelopmental disorder with underlying synaptic dysfunction.
Mark A Deehan, Josine M Kothuis, Ellen Sapp, Kathryn Chase, Yuting Ke, Connor Seeley, Maria Iuliano, Emily Kim, Lori Kennington, Rachael Miller, Adel Boudi, Kai Shing, Xueyi Li, Edith Pfister, Christelle Anaclet, Michael Brodsky, Kimberly Kegel-Gleason, Neil Aronin, Marian DiFiglia
A missense mutation in the transcription repressor Nucleus accumbens-associated 1 ( NACC1 ) gene at c.892C>T (p.Arg298Trp) on chromosome 19 causes severe neurodevelopmental delay (Schoch et al 2017). To model this disorder, we engineered the first mouse model with the homologous mutation ( Nacc1+/R284W ) and examined mice from E17.5 to 8 months. Both genders had delayed weight gain, epileptiform discharges and altered power spectral distribution in cortical electroencephalogram (EEG), behavioral seizures, and marked hindlimb clasping; females displayed thigmotaxis in an open field...
February 22, 2024: Journal of Neuroscience
#13
JOURNAL ARTICLE
Alicia M Trbovich, Anne Mucha, Aaron J Zynda, Taylor Farley, Nathan Kegel, Vanessa Fazio, Michael W Collins, Anthony P Kontos
OBJECTIVE: To determine which components from a multidomain assessment best predict protracted recovery in pediatric patients with a concussion. STUDY DESIGN: A prospective cohort of patients aged 5-9 years who presented within 21 days of concussion to a specialty clinic were categorized into normal (≤30 days) and protracted (>30 days) recovery. Participants provided demographic and medical history information, and completed the Child Sport Concussion Assessment Tool-5 symptom report and balance assessment, the Vestibular/Ocular Motor Screen-Child (VOMS-C), and the Pediatric Immediate Post-concussion Assessment and Cognitive Testing...
February 1, 2024: Journal of Pediatrics
#14
JOURNAL ARTICLE
Li Zhang, Sheng Zhao, Sisi Wu, Yan Luo, Yinfang Wang, Xiaotian Fu, Dan Wang, Yuhan Wu
OBJECTIVE: To explore the application of four-dimensional pelvic floor ultrasound in the diagnosis of postpartum pelvic floor dysfunction (PFD) and evaluation of curative effect. METHODS: A total of 100 patients with postpartum PFD undergoing vaginal delivery in the hospital were enrolled as the research objects between January 2020 and January 2023. A total of 100 postpartum women with good pelvic floor muscle function during the same period were enrolled as a control group...
January 1, 2024: Alternative Therapies in Health and Medicine
#15
REVIEW
Kari Bø
INTRODUCTION: Functional bladder outlet obstruction (BOO) in women is postulated to be caused by pelvic floor muscle (PFM) dyssynergia or increased tone. The aim of the present review was to investigate the effect of PFM relaxation training on PFM tone and female BOO symptoms. MATERIALS AND METHODS: This was a narrative review using an open search strategy on PubMed with the search terms "Bladder outlet obstruction" AND "female" AND ("pelvic floor muscles" OR "Kegel")...
January 30, 2024: Neurourology and Urodynamics
#16
JOURNAL ARTICLE
Josua Kegele, Thomas Wagner, Teresa Kowenski, Matthias Wiesmayr, Christian Gatterer, Michael Alber, Wiliam Matuja, Erich Schmutzhard, Holger Lerche, Andrea S Winkler
Nodding Syndrome is a poorly understood epilepsy disorder in sub-Saharan Africa. The cause(s) of the disease, risk factors and long-term outcomes are unknown or controversial. The objectives of this study were to describe the long-term clinical course and treatment outcomes of individuals suffering from Nodding Syndrome. In addition, we aimed to provide a comprehensive characterization of the epileptological and social features of patients with Nodding Syndrome. From 11/2014 to 4/2015, we conducted a hospital-based, cross-sectional and observational study in Mahenge, Tanzania...
February 15, 2024: Journal of the Neurological Sciences
#17
JOURNAL ARTICLE
Tram Thi Bich Nguyen, Yu-Yun Hsu, Yanti Puspita Sari
BACKGROUND: Genitourinary syndrome is commonly reported in postmenopausal women. Kegel's exercise is a noninvasive therapy that improves pelvic floor muscle parameters. However, the effect of Kegel's exercise on health-related quality of life (HRQoL) in postmenopausal women with genitourinary syndrome has not been synthesized or shown. PURPOSE: This study was designed to systematically review and analyze the previous literature to determine whether Kegel's exercise enhances HRQoL in postmenopausal women with genitourinary syndrome of menopause...
January 1, 2024: Journal of Nursing Research: JNR
#18
JOURNAL ARTICLE
Almaqdad Alsalloum, Walaa Asaad, Julia Krupinova, Evgenii Kegeles, Polina Sirotkina, Alexandra Panova, Olga Mityaeva, Pavel Volchkov
CDC73-related disorders are inherited in an autosomal dominant manner. An individual with a CDC73-related disorder may have inherited the disorder from an affected parent or developed it as the result of a de novo pathogenic variant of CDC73. The iPSC line was obtained by reprogramming the PBMCs of a patient with a heterozygous type mutation of the CDC73 gene. This cell line could be useful to scrutinize and study the development of CDC73-associated parathyroid carcinoma.
January 10, 2024: Stem Cell Research
#19
JOURNAL ARTICLE
Jinling Dai, Zhu Jin, Xiaojin Zhang, Feng Lian, Jie Tu
INTRODUCTION AND HYPOTHESIS: The objective was to observe the clinical efficacy of warm acupuncture combined with Kegel exercise in treating postpartum pelvic floor dysfunction in women. METHODS: A total of 70 primiparous women with postpartum pelvic floor muscle (PFM) injury were randomly divided into a combination group (n = 35, receiving warm acupuncture at Zhibian (BL54) acupoint and Kegel exercise) and a sham control group (n = 35, receiving sham warm acupuncture and Kegel exercise)...
January 18, 2024: International Urogynecology Journal
#20
JOURNAL ARTICLE
Anna Kegel, Jason Espinoza, April Rahrig, Tina Schade-Wills, Courtney M Rowan
Background: Understanding interventions preceding death in children with immunocompromised conditions is important to ensure a peaceful and dignified perideath experience. The aim of this study was to describe the number of interventions performed in the pediatric intensive care unit (PICU) within the 48 hours before death in this population. Methods: This was a single-center, retrospective cohort study of all children with an underlying oncologic, hematologic, or immunologic diagnosis admitted to the PICU for at least 72 hours between 2014 and 2021...
January 17, 2024: Journal of Palliative Medicine
Make the most of Read.
Download the mobile app.
Download the mobile app.
Fetching more papers... 
