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https://read.qxmd.com/read/30622569/melkersson-rosenthal-syndrome-a-case-report-of-a-rare-disease-with-overlapping-features
#1
Mauro Cancian, Stefano Giovannini, Annalisa Angelini, Marny Fedrigo, Raffaele Bendo, Riccardo Senter, Stefano Sivolella
Background: Melkersson-Rosenthal syndrome (MRS) is a rare, neuro-mucocutaneous disease which presents as orofacial swelling, facial palsy and fissured tongue. These symptoms may occur simultaneously or, more frequently, with a oligosymptomatic or monosymptomatic pattern. Swelling, that is the most common initial finding, may mimic hereditary or acquired angioedema, a disorder caused by histamine or bradykinin-mediated plasma-leakage affecting subcutaneous and/or submucosal tissue. The differential diagnosis of MRS includes also chronic inflammatory and infective diseases characterized by granulomatous infiltration, as well as rosacea, contact dermatitis, allergic reactions and Bell's palsy...
2019: Allergy, Asthma, and Clinical Immunology
https://read.qxmd.com/read/30567440/correlation-between-halitosis-oral-health-status-and-salivary-%C3%A3-galactosidases-and-time-spent-in-physical-activities-in-children
#2
M Petrini, M Costacurta, V Biferi, D Benavoli, R Docimo, G Spoto
AIM: The aim of this work was to evaluate the oral health status in children and to correlate it with time spent in physical activity per week. MATERIALS AND METHODS: Fifty children (mean age 9±2 years) attending the first visit at the Paediatric Dental Unit of the University of Rome "Tor Vergata" have been included in the study. The parents of all patients were interviewed about the medical history of the children and specific data, in particular, the time spent in physical activity per week...
December 2018: European Journal of Paediatric Dentistry: Official Journal of European Academy of Paediatric Dentistry
https://read.qxmd.com/read/30217753/clinical-and-genetic-heterogeneity-in-melkersson-rosenthal-syndrome
#3
Yang Pei, Glenda M Beaman, David Mansfield, Jill Clayton-Smith, Murray Stewart, William G Newman
Melkersson Rosenthal syndromes (MRS) is a rare autosomal dominantly inherited neurocutaneous syndrome characterised by a triad of facial (seventh cranial) nerve palsy, recurrent orofacial swelling and fissuring of the tongue. A recent report implicated a heterozygous missense variant in SLC27A1 (FATP1) as the cause of this condition in members of an affected Chinese family. We undertook Sanger sequencing of this gene in 14 affected unrelated individuals affected by MRS. We did not detect any putative pathogenic variants...
September 11, 2018: European Journal of Medical Genetics
https://read.qxmd.com/read/30008454/tongue-atrophy-in-sj%C3%A3-gren-syndrome-patients-with-mucosa-associated-lymphoid-tissue-lymphoma-autoimmune-epithelitis-beyond-the-epithelial-cells-of-salivary-glands
#4
Evangelia Zampeli, Eleni-Marina Kalogirou, Evangelia Piperi, Clio P Mavragani, Haralampos M Moutsopoulos
OBJECTIVE: Primary Sjögren syndrome (pSS), an autoimmune epithelitis, bears the risk of evolving to non-Hodgkin lymphoma and most frequently to the mucosa-associated lymphoid tissue (MALT) subtype. Based on the observation that pSS patients with MALT present a more atrophic and more intensely fissured tongue, we aimed to semiquantify severity of tongue atrophy and clinically assess lingual appearance in pSS patients with and without MALT, and investigate whether tongue atrophy and fissured appearance could serve as clinical indicators/signs of MALT...
November 2018: Journal of Rheumatology
https://read.qxmd.com/read/29984016/melkersson-rosenthal-syndrome-a-rare-cause-of-recurrent-facial-nerve-palsy-and-acute-respiratory-distress-syndrome
#5
Behiye Deniz Kosovali, Asiye Yavuz, Fatma Irem Yesiler, Mustafa Kemal Bayar
Melkersson-Rosenthal Syndrome (MRS) is a rare disease characterized by persistent or recurrent orofacial oedema, relapsing peripheral facial paralysis, and furrowed tongue. Pathologically, granulomatosis is responsible for oedema of face, labia, oral cavity, and facial nerve. We present a patient with MRS admitted to our hospital with acute respiratory distress syndrome (ARDS). 45-year-old woman was admitted to an emergency department with dyspnea and swelling on her hands and face. She was intubated because of ARDS and accepted to intensive care unit (ICU)...
2018: Case Reports in Neurological Medicine
https://read.qxmd.com/read/29931652/anatomical-investigations-of-the-tongue-and-laryngeal-entrance-of-the-egyptian-laughing-dove-spilopelia-senegalensis-aegyptiaca-in-egypt
#6
Mohamed M A Abumandour, Neveen E R El-Bakary
In the present work, the first full anatomical description of the tongue and laryngeal entrance of the Egyptian laughing dove Spilopelia senegalensis aegyptiaca, which was obtained with the aid of scanning electron microscopy (SEM) and histological techniques, is provided. The lingual apex was rounded and the cranially convex papillary crest exhibited a transverse papillary row, in addition to another row consisting of two giant papillae. Papillae were not observed on the elevated, triangular laryngeal mound except for the glottic opening, which was bounded by two lateral elevated borders that presented a row of small papillae...
June 21, 2018: Anatomical Science International
https://read.qxmd.com/read/29924754/oral-lesions-in-sjogren-s-syndrome-a-systematic-review
#7
J Serrano, R-M Lopez-Pintor, J Gonzalez-Serrano, M Fernandez-Castro, E Casanas, G Hernandez
BACKGROUND: Sjogren's syndrome (SS) is an autoimmune disease related to two common symptoms: dry mouth and eyes. Although, xerostomia and hyposialia have been frequently reported in these patients, not many studies have evaluated other oral manifestations. The aim of this systematic review was to investigate prevalence rates of oral lesions (OL) in SS patients and to compare it to a control group (CG), when available. MATERIAL AND METHODS: An exhaustive search of the published literature of the Pubmed, Scopus, Web of Science and the Cochrane Library databases was conducted according to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses Protocols (PRISMA-P) for relevant studies that met our eligibility criteria (up to September 1st 2017)...
July 1, 2018: Medicina Oral, Patología Oral y Cirugía Bucal
https://read.qxmd.com/read/29904177/phenotypic-spectrum-of-au-kline-syndrome-a-report-of-six-new-cases-and-review-of-the-literature
#8
P Y Billie Au, Caitlin Goedhart, Marcia Ferguson, Jeroen Breckpot, Koenraad Devriendt, Klaas Wierenga, Elizabeth Fanning, Dorothy K Grange, Gail E Graham, Carolina Galarreta, Marilyn C Jones, Usha Kini, Helen Stewart, Jillian S Parboosingh, Antonie D Kline, A Micheil Innes
Au-Kline syndrome (AKS, OMIM 616580) is a multiple malformation syndrome, first reported in 2015, associated with intellectual disability. AKS has been associated with de novo loss-of-function variants in HNRNPK (heterogeneous ribonucleoprotein K), and to date, only four of these patients have been described in the literature. Recently, an additional patient with a missense variant in HNRNPK was also reported. These patients have striking facial dysmorphic features, including long palpebral fissures, ptosis, deeply grooved tongue, broad nose, and down-turned mouth...
June 14, 2018: European Journal of Human Genetics: EJHG
https://read.qxmd.com/read/29893310/tooth-agenesis-a-susceptible-indicator-for-colorectal-cancer
#9
M V Paranjyothi, K L Kumaraswamy, Lubna Firdose Begum, K Manjunath, Shaini Basheer
Context/Background: Tooth agenesis (excluding third molars) is a common congenital disorder that affects 2.2-10% of the general population. A number of different genes have been shown to be associated with cases of tooth agenesis including AXIN2, IRF6, FGFR1, MSX1, PAX9, and TGFA. Wingless/integration signaling gene, AXIN2, is linked to tooth agenesis and also to colorectal cancer (CRC). Aims: To analyze the correlation between tooth agenesis and CRC. Materials and Methods: The study included 50 individuals, who were divided into two groups...
April 2018: Journal of Cancer Research and Therapeutics
https://read.qxmd.com/read/29887889/prevalence-and-distribution-of-oral-mucosal-lesions-by-sex-and-age-categories-a-retrospective-study-of-patients-attending-lebanese-school-of-dentistry
#10
Sami El Toum, Antoine Cassia, Nermine Bouchi, Issam Kassab
Background: Prevalence and distribution of oral mucosal lesions in a sample of Lebanese population attending the School of Dentistry of Lebanese University is necessary to evaluate their oral health situation. Objectives: The aim of the present study was to determine the prevalence and distribution of oral mucosal lesions of patients attending the School of Dentistry. Methods: A descriptive study was carried out by retrospectively examining a total of 231 medical and clinical examination record files of patients, attending the School of Dentistry Lebanese University for multidisciplinary dental treatments...
2018: International Journal of Dentistry
https://read.qxmd.com/read/29773283/tongue-psoriasis-clinical-aspects-and-analysis-of-epidemiological-associations-in-313-children-with-a-systematic-literature-review
#11
D Pourchot, C Chiaverini, E Bourrat, S Barbarot, P Vabres, T Hubiche, C Droicourt, M Piram, I Kupfer-Bessaguet, M Ferneiny, E Puzenat, X Balguérie, A Beauchet, A-C Bursztejn, E Mahé
BACKGROUND: Little information is available on the prevalence and clinical aspects of tongue involvement in children with psoriasis. The aim was to evaluate the prevalence, clinical aspects and risk factors concerning tongue involvement in children with psoriasis. PATIENTS AND METHODS: This study was carried out in two stages. We performed a multicentre, cross-sectional study in 23 French dermatology centers. All children seen for psoriasis during the one-year study were systematically included...
October 2018: Annales de Dermatologie et de Vénéréologie
https://read.qxmd.com/read/29575224/oral-psoriasis-and-sibo-is-there-a-link
#12
LETTER
F Drago, G Ciccarese, V Cordara, M Paudice, A Herzum, A Parodi
No abstract text is available yet for this article.
September 2018: Journal of the European Academy of Dermatology and Venereology: JEADV
https://read.qxmd.com/read/29480863/tongue-diagnosis-indices-for-upper-gastrointestinal-disorders-protocol-for-a-cross-sectional-case-controlled-observational-study
#13
Tzu-Chan Wu, Keng-Liang Wu, Wen-Long Hu, Jer-Ming Sheen, Cheng-Nan Lu, John Y Chiang, Yu-Chiang Hung
BACKGROUND: Upper gastrointestinal disorders are common in clinical practice, for example, gastritis, peptic ulcer disease, and gastroesophageal reflux disease. Panendoscopy or upper gastrointestinal endoscopy is viewed as the primary tool for examining the upper gastrointestinal mucosa, and permitting biopsy and endoscopic therapy. Although panendoscopy is considered to be a safe procedure with minimal complications, there are still some adverse effects, and patients are often anxious about undergoing invasive procedures...
January 2018: Medicine (Baltimore)
https://read.qxmd.com/read/29362631/prevalence-of-oral-mucosal-lesions-and-their-association-with-severity-of-psoriasis-among-psoriatic-patients-referred-to-dermatology-clinic-a-cross-sectional-study-in-kashan-iran
#14
Rezvan Talaee, Zohreh Hajheydari, Ahmad Yeganeh Moghaddam, Seyyed Alireza Moraveji, Bentolhoda Fatahi Ravandi
BACKGROUND: Psoriasis is a common inflammatory papulosquamous disease of the skin with unknown aetiology that may be associated with the abnormal T-cell function. AIM: This study was aimed to determine the prevalence of oral mucosal lesions and their associations with severity of psoriasis in psoriatic patients attending the dermatologic clinic of Shahid Beheshti Teaching Hospital at Kashan, Iran. METHODS: In this cross-sectional descriptive analytic study, all consecutive patients with psoriasis who referred to the dermatologic clinic at the Shahid Beheshti Hospital of Kashan University of Medical Sciences in Kashan City/ Iran were enrolled...
December 15, 2017: Open Access Macedonian Journal of Medical Sciences
https://read.qxmd.com/read/29332713/fissured-tongue-in-patients-with-psoriasis
#15
LETTER
Bruna Lavinas Sayed Picciani, Thays Teixeira-Souza, Thiago Moreira Pessôa, Lívia Maria Santos Izahias, Jane Marcy Neffa Pinto, David Rubem Azulay, João Carlos Regazzi Avelleira, Sueli Carneiro, Eliane Pedra Dias
No abstract text is available yet for this article.
February 2018: Journal of the American Academy of Dermatology
https://read.qxmd.com/read/29065902/treatment-of-orofacial-granulomatosis-a-case-report
#16
Maaz B Badshah, Saqib Walayat, Umair Ahmed, Sonu Dhillon, Sherri Yong, Sunanda Kane, Shoba Thievanayagam
BACKGROUND: Orofacial granulomatosis is a relatively recent term coined by Wiesenfield et al. in 1985 to define granulomatous lesions of oral mucosa without intestinal involvement. When it presents in a triad encompassing facial nerve palsy, lip swelling, and fissured or furrowed tongue it is called Melkersson-Rosenthal syndrome while monosymptomatic or oligosymptomatic forms are referred to as granulomatous cheilitis. It is an uncommon clinicopathologic entity which is distinct from classic Crohn's disease...
October 25, 2017: Journal of Medical Case Reports
https://read.qxmd.com/read/28955595/dental-management-and-orofacial-manifestations-of-a-patient-with-robinow-syndrome
#17
Adil Basman, Gulsun Akay, Ilkay Peker, Kahraman Gungor, Zuhre Akarslan, Suat Ozcan, Cemile Ozlem Ucok
Robinow syndrome (RS) is an extremely rare condition. Characteristic craniofacial findings of RS include a fetal facial appearance, ear abnormalities and oral findings. The aim of this case report was to evaluate the oral findings of a 26-year-old man with RS and to describe the dental treatments performed. The patient had short stature, vertebral anomalies, short and broad fingers, a fetal facial appearance, gingival hyperplasia, fissured tongue, caries and multiple impacted teeth. Periodontal and restorative dental treatments were performed under aseptic conditions with due precautions...
2017: Journal of Istanbul University Faculty of Dentistry
https://read.qxmd.com/read/28955585/melkersson-rosenthal-syndrome-a-case-report
#18
Adil Basman, Mustafa Gumusok, Serife Degerli, Mustafa Kaya, Meryem Toraman Alkurt
Melkersson-Rosenthal Syndrome (MRS) is a rare disorder consisting of a triad of persistent or recurrent orofacial edema, relapsing facial paralysis and fissured tongue. It is rarely possible to observe all aspects of the classical triad at the same time, since these symptoms may appear in different times of life cycle. The most common symptom is orofacial edema. Although etiology of MRS is unclear, various factors such as infections, genetic predisposition, immune deficiency, food intolerance and stress have been held responsible...
2017: Journal of Istanbul University Faculty of Dentistry
https://read.qxmd.com/read/28905102/digestive-system-in-psoriasis-an-update
#19
REVIEW
Daniel Pietrzak, Aldona Pietrzak, Dorota Krasowska, Andrzej Borzęcki, Kinga Franciszkiewicz-Pietrzak, Beata Polkowska-Pruszyńska, Maja Baranowska, Kristian Reich
Psoriasis is a chronic inflammatory immune-mediated disorder associated and often coexisting with many other immune-related clinical conditions including those affecting the gastrointestinal tract. Data obtained from the reviewed literature suggest an association between psoriasis and pathologies of the oral cavity, both psoriasis-specific lesions, as well as non-specific, such as geographic tongue or fissured tongue. These findings show the importance of thorough examination of oral mucosa in psoriatic patients...
November 2017: Archives of Dermatological Research
https://read.qxmd.com/read/28859733/hidradenitis-suppurativa-and-concomitant-down-syndrome-literature-review-of-other-associated-mucocutaneous-manifestations-in-adults
#20
Virendra N Sehgal, Naresh Sehgal, Ruchi Sehgal
This contribution describes hidradenitis suppurativa (HS) occurring in Down disease that presented with morphology conforming to an overlap of stages 1 and 2 of the Hurley staging system, namely the formation of solitary or multiple isolated abscesses without scarring or sinus tracts, recurrent abscesses, and single or multiple widely separated lesions with sinus tract formation, occupying apocrine sweat gland-bearing areas: the inner thighs, groin, and buttocks. The lesions were bilateral and symmetrical, of rare occurrence...
2017: Skinmed
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