Fabrizio Vallelonga, Matteo Valente, Marta Maria Tangari, Anna Covolo, Valeria Milazzo, Cristina Di Stefano, Gabriele Sobrero, Marta Giudici, Alberto Milan, Franco Veglio, Leonardo Lopiano, Simona Maule, Alberto Romagnolo
PURPOSE: Neurogenic orthostatic hypotension (nOH) is a frequent nonmotor feature of Parkinson's disease (PD), associated with adverse outcomes. Recently, 24-h ambulatory blood pressure monitoring (ABPM) showed good accuracy in diagnosing nOH. This study aims at evaluating the prognostic role of ABPM-hypotensive episodes in predicting PD disability milestones and mortality and comparing it to the well-defined prognostic role of bedside nOH. METHODS: Patients with PD who underwent ABPM from January 2012 to December 2014 were retrospectively enrolled and assessed for the development of falls, fractures, dementia, bed/wheelchair confinement, hospitalization, and mortality, during an up-to-10-year follow-up...
April 25, 2024: Clinical Autonomic Research: Official Journal of the Clinical Autonomic Research Society