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RANDOMIZED CONTROLLED TRIAL
Adam C Cunningham, Carley Prentice, Kimberly Peven, Aidan Wickham, Ryan Bamford, Tara Radovic, Anna Klepchukova, Maria Fomina, Katja Cunningham, Sarah Hill, Liisa Hantsoo, Jennifer Payne, Liudmila Zhaunova, Sonia Ponzo
BACKGROUND: Reproductive health literacy and menstrual health awareness play a crucial role in ensuring the health and well-being of women and people who menstruate. Further, awareness of one's own menstrual cycle patterns and associated symptoms can help individuals identify and manage conditions of the menstrual cycle such as premenstrual syndrome (PMS) and premenstrual dysphoric disorder (PMDD). Digital health products, and specifically menstrual health apps, have the potential to effect positive change due to their scalability and ease of access...
May 2, 2024: JMIR MHealth and UHealth
#2
JOURNAL ARTICLE
Li'ang Yu, Hayley Sussman, Olga Khmelnitsky, Maryam Rahmati Ishka, Aparna Srinivasan, Andrew D L Nelson, Magdalena M Julkowska
Nondestructive plant phenotyping forms a key technique for unraveling molecular processes underlying plant development and response to the environment. While the emergence of high-throughput phenotyping facilities can further our understanding of plant development and stress responses, their high costs greatly hinder scientific progress. To democratize high-throughput plant phenotyping, we developed sets of low-cost image- and weight-based devices to monitor plant shoot growth and evapotranspiration. We paired these devices to a suite of computational pipelines for integrated and straightforward data analysis...
May 3, 2024: Plant Physiology
#3
JOURNAL ARTICLE
Beatriz Molina Carvalho, Maria Cândida de Carvalho Furtado, Gustavo Travaini Chinalia, Edilson Carlos Caritá, Gabriel Zanin Sanguino
OBJECTIVE: to develop and validate a mobile application for teaching undergraduates about the first nursing visit to a newborn in primary care. METHOD: methodological study with an Instructional Design framework; content drawn up from scientific documents on caring for newborns and their families, supported by the results of an integrative review on the subject. The Integrated Development Environment Android Studio 4.0.1 tool and the IntelliJ IDEA platform were used to build the digital technology...
2024: Revista Latino-americana de Enfermagem
#4
JOURNAL ARTICLE
Fernando K Malerbi, Luis Filipe Nakayama, Gustavo Barreto Melo, José A Stuchi, Diego Lencione, Paulo V Prado, Lucas Z Ribeiro, Sergio A Dib, Caio V Regatieri
PURPOSE: To evaluate the performance of artificial intelligence (AI) systems embedded in a mobile, handheld retinal camera, with a single retinal image protocol, in detecting both diabetic retinopathy (DR) and more-than-mild diabetic retinopathy (mtmDR). DESIGN: Multicenter cross-sectional diagnostic study, conducted at 3 diabetes care and eye care facilities. PARTICIPANTS: A total of 327 individuals with diabetes mellitus (type 1 or type 2) underwent a retinal imaging protocol enabling expert reading and automated analysis...
2024: Ophthalmol Sci
#5
JOURNAL ARTICLE
John F Hoops, Troy L Hooper, Stéphane Sobczak, Jeegisha Kapila, Birendra M Dewan, Omer C Matthijs, Jean-Michel Brismée
[Purpose] To compare humeral head translation (HHT) during shoulder elevation between dominant and non-dominant shoulders in participants with limited dominant shoulder internal rotation range of motion (ROM). To determine if joint mobilization alters HHT, and if relationships exist between the bicipital forearm angle and HHT. [Participants and Methods] Fifteen (9 female) participants (age 25.7 ± 6.8 years) with a minimum 15-degree dominant shoulder internal rotation ROM deficit compared to the opposite shoulder participated...
May 2024: Journal of Physical Therapy Science
#6
JOURNAL ARTICLE
Tim Gossye, Dimitri Buytaert, Peter V Smeets, Lieve Morbée, Elke Vereecke, Pieter-Jan Kellens, Eric Achten, Klaus Bacher
BACKGROUND: A physical scatter grid is not often used in pelvic bedside examinations. However, multiple studies regarding scatter correction software (SC SW) are available for mobile chest radiography but the results are unclear for pelvic radiography. PURPOSE: We evaluated SC SW of Fujifilm (Virtual Grid) on gridless pelvic radiographs obtained from a human Thiel-embalmed body to investigate the potential of Virtual Grid in pelvic bedside examinations. METHODS: Gridless, Virtual Grid, and physical grid pelvic radiographs of a female Thiel-embalmed body were collected with a broad range of tube loads...
May 1, 2024: Journal of Applied Clinical Medical Physics
#7
JOURNAL ARTICLE
Yuliana Jiménez-Gaona, María José Rodríguez Álvarez, Darwin Castillo-Malla, Santiago García-Jaen, Diana Carrión-Figueroa, Patricio Corral-Domínguez, Vasudevan Lakshminarayanan
Mobile health apps are widely used for breast cancer detection using artificial intelligence algorithms, providing radiologists with second opinions and reducing false diagnoses. This study aims to develop an open-source mobile app named "BraNet" for 2D breast imaging segmentation and classification using deep learning algorithms. During the phase off-line, an SNGAN model was previously trained for synthetic image generation, and subsequently, these images were used to pre-trained SAM and ResNet18 segmentation and classification models...
May 2, 2024: Medical & Biological Engineering & Computing
#8
JOURNAL ARTICLE
Ruidong Meng, Zhicheng Yu, Qiang Fu, Yi Fan, Li Fu, Zixuan Ding, Shuo Yang, Zhanmao Cao, Li Jia
Smartphone-based digital image colorimetry is a powerful, fast, low-cost approach to detecting target analytes. However, lighting conditions and camera parameters easily affect the detection results, significantly curtailing its applicability in multiple scenarios. In this study, an Android-based mobile application (SMP-CC) is developed, which offers a comprehensive package that includes image acquisition, color correction, and colorimetric analysis functions. Using a custom color card, a built-in algorithm in SMP-CC can minimize the color difference between the standard color block image captured by different smartphones under different lighting conditions and the standard value by an LS171 colorimeter less than 4...
April 26, 2024: Spectrochimica Acta. Part A, Molecular and Biomolecular Spectroscopy
#9
JOURNAL ARTICLE
Giulia Consiglieri, Francesca Tucci, Maurizio De Pellegrin, Barbara Guerrini, Alessandro Cattoni, Giulia Risca, Stefano Scarparo, Marina Sarzana, Silvia Pontesilli, Renata Mellone, Serena Gasperini, Stefania Galimberti, Paolo Silvani, Chiara Filisetti, Silvia Darin, Giulia Forni, Simona Miglietta, Ludovica Santi, Marcella Facchini, Ambra Corti, Francesca Fumagalli, Maria Pia Cicalese, Valeria Calbi, Maddalena Migliavacca, Federica Barzaghi, Francesca Ferrua, Vera Gallo, Salvatore Recupero, Daniele Canarutto, Matteo Doglio, Lucia Tedesco, Nicola Volpi, Attilio Rovelli, Giancarlo la Marca, Maria Grazia Valsecchi, Stefano Zancan, Fabio Ciceri, Luigi Naldini, Cristina Baldoli, Rossella Parini, Bernhard Gentner, Alessandro Aiuti, Maria Ester Bernardo
Mucopolysaccharidosis type I Hurler (MPSIH) is characterized by severe and progressive skeletal dysplasia that is not fully addressed by allogeneic hematopoietic stem cell transplantation (HSCT). Autologous hematopoietic stem progenitor cell-gene therapy (HSPC-GT) provides superior metabolic correction in patients with MPSIH compared with HSCT; however, its ability to affect skeletal manifestations is unknown. Eight patients with MPSIH (mean age at treatment: 1.9 years) received lentiviral-based HSPC-GT in a phase 1/2 clinical trial (NCT03488394)...
May 2024: Science Translational Medicine
#10
JOURNAL ARTICLE
Elise Hoover, Vanessa Holliday, Nicole Merullo, Dorothee Oberdhan, Ronald D Perrone, Chris Rusconi, Meyeon Park, Milind A Phadnis, Nadeesha Thewarapperuma, Neera K Dahl
RATIONALE & OBJECTIVE: Autosomal dominant polycystic kidney disease (ADPKD) affects health-related quality of life (HRQoL) including pain, discomfort, fatigue, emotional distress, and impaired mobility. Stakeholders prioritized kidney cyst-related pain as an important core outcome domain in clinical trials, leading to the development of disease-specific assessment tools. STUDY DESIGN: The ADPKD Registry is hosted online with multiple disease-specific patient-reported outcomes modules to characterize the patient experience in the United States...
May 2024: Kidney medicine
#11
JOURNAL ARTICLE
Katharina Storck, Siegfried Ussar, Sebastian Kotz, Irem Altun, Fiona Hu, Amelie Birk, Johannes Veit, Milos Kovacevic
Septorhinoplasty (SRP) is one of the most common aesthetic procedures worldwide. A thin or scarred soft tissue envelope, especially in the context of secondary SRP, can lead to unpredictable scarring, shrinkage, and discoloration of the skin. Other than the careful preparation of the soft tissue mantle, no gold standard exists to minimize the above-mentioned risks. Our aim was to create a thin "separation layer" between the nasal bridge (osseous and cartilaginous) and the skin envelope by autologous fat transfer with the addition of platelet-rich fibrin (PRF) to conceal small irregularities, to improve the quality of the skin soft tissue mantle, and to optimize the mobility of the skin...
April 30, 2024: Facial Plastic Surgery: FPS
#12
JOURNAL ARTICLE
Odran Pivot, Sandrine Voros, Christine Chappard, Guillaume Bernard, Yannick Grondin, Laurent Desbat
BACKGROUND: Accurate tomographic reconstructions require the knowledge of the actual acquisition geometry. Many mobile C-arm CT scanners have poorly reproducible acquisition geometries and thus need acquisition-specific calibration procedures. Most of geometric self-calibration methods based on projection data either need prior information or are limited to the estimation of a low number of geometric calibration parameters. Other self-calibration methods generally use a calibration pattern with known geometry and are hardly implementable in practice for clinical applications...
April 30, 2024: Medical Physics
#13
JOURNAL ARTICLE
Adam C Monek, Rida Mitha, Edward Andrews, Inderpal S Sarkaria, Nitin Agarwal, D Kojo Hamilton
BACKGROUND AND IMPORTANCE: In adults, primary spinal cord tumors account for 5% of all primary tumors of the central nervous system, with schwannomas making up about 74% of all nerve sheath tumors. Thoracic schwannomas can pose a threat to neurovasculature, presenting a significant challenge to safe and complete surgical resection. For patients presenting with complex pathologies including tumors, a dual surgeon approach may be used to optimize patient care and improve outcomes. CLINICAL PRESENTATION: A 73-year-old female previously diagnosed with a nerve sheath tumor of the fourth thoracic vertebra presented with significant thoracic pain and a history of falls...
April 30, 2024: Operative Neurosurgery (Hagerstown, Md.)
#14
JOURNAL ARTICLE
Jeongmin Han, Sumi Choi, Jinwoo Hong, Dayeong Gang, Seunghoon Lee, Kwangsoo Shin, Junghyeon Ko, Jeong-Uk Kim, Nathaniel S Hwang, Young-Hyeon An, Minsu Gu, Su-Hwan Kim
Polyphenols have been investigated for their potential to mitigate inflammation in the context of atopic dermatitis (AD). In this study, epigallocatechin-3-gallate (EGCG)-based carbon dots (EGCG@CDs) were developed to enhance transdermal penetration, reduce inflammation, recapitulate superoxide dismutase (SOD) activity, and provide antimicrobial effects for AD treatment. The water-soluble EGCG@CDs in a few nanometers size exhibit a negative zeta potential, making them suitable for effective transdermal penetration...
April 30, 2024: ACS Applied Materials & Interfaces
#15
JOURNAL ARTICLE
Keisuke Kokubun, Kiyotaka Nemoto, Yoshinori Yamakawa
INTRODUCTION: The number of smartphone apps for brain training is increasing, and the number of people who are working on brain training is also increasing. However, researchers disagree about the effectiveness of brain training. METHODS: Therefore, in this study, we conducted an intervention test with the participation of 70 healthy middle-aged men and women and measured the effect of smartphone apps on lifestyle improvement using brain healthcare quotient calculated from brain imaging data...
May 2024: Brain and Behavior
#16
JOURNAL ARTICLE
Anna-Lena Zepernick, Vanya Metodieva, Noelia Pelegrina-Hidalgo, Anna H Lippert, Mathew H Horrocks, Juan A Varela
Aquaporin-4 (AQP4) facilitates water transport across astrocytic membranes in the brain, forming highly structured nanometric arrays. AQP4 has a central role in regulating cerebrospinal fluid (CSF) circulation and facilitating the clearance of solutes from the extracellular space of the brain. Adrenergic signaling has been shown to modulate the volume of the extracellular space of the brain via AQP4 localized at the end-feet of astrocytes, but the mechanisms by which AQP4 regulates CSF inflow and outflow in the brain remain elusive...
April 29, 2024: Nanoscale
#17
JOURNAL ARTICLE
Manisha Koneru, Hamza A Shaikh, Daniel A Tonetti, James E Siegler, Jane Khalife, Ajith J Thomas, Tudor G Jovin, Corey M Mossop
Objective Identifying ischemic stroke is a diagnostic challenge in the trauma subpopulation. We describe our early experience with artificial intelligence-assisted image analysis software for automatically identifying acute ischemic stroke in trauma patients. Methods Patients were retrospectively screened for (i) admission to the trauma service at a level one trauma center between 2020 and 2022, (ii) radiologist-confirmed intracranial occlusion, (iii) occlusion identified on computed tomography angiography performed within 24 hours of admission, (iv) no intracranial hemorrhage, and (v) contemporaneous analysis with the large vessel occlusion (LVO) detection program...
March 2024: Curēus
#18
Nandini V Zore, H V Sharath, Nikita Gangwani
Discitis linked to Pott's spine is an infrequent yet severe issue, especially difficult to manage among elderly individuals due to age-related bodily changes and concurrent health issues. This report details the successful physiotherapy-based recovery of a senior patient afflicted with discitis related to Pott's spine. The individual, a 61-year-old man, presented symptoms including intense back pain, restricted movement, and neurological issues. The diagnosis was confirmed via imaging scans, indicating spinal tuberculosis and vertebral disc involvement...
March 2024: Curēus
#19
Ghanishtha C Burile, Raghumahanti Raghuveer, Vaibhav Chandankhede, Shrushti Jachak, Neha Arya
Glioblastoma is the most prevalent primary brain tumor. Because glioblastomas are very vascular, they may worsen the disease's neurologic symptoms by causing vasogenic brain edema and mass effects with a wide range of other symptoms. In this case report, a 42-year-old male complaining of severe headache, generalized weakness, and forgetfulness was brought to a territory care hospital, where a detailed neurological examination and investigations with magnetic resonance imaging (MRI) revealed a grade IV (high-grade) glioma at the right frontotemporal and capsuloganglionic regions of the brain, and was suggested for surgery...
March 2024: Curēus
#20
Yuka Kodama, Kenji Matsumoto, Hisashi Kubota, Onichi Furuya, Yoshio Kawase
BACKGROUND: Left ventricular thrombus (LVT) formation is a serious complication of acute myocardial infarction (AMI) requiring complicated management strategies and collaboration among cardiologists, cardiovascular surgeons, and neurosurgeons. CASE SUMMARY: We present the case of an 83-year-old female patient with AMI. Emergency coronary angiography revealed subtotal occlusion of the proximal left anterior descending artery, and the patient was successfully treated with a drug-eluting stent...
April 2024: European Heart Journal. Case Reports
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