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JOURNAL ARTICLE
Rachel S Gross, Tanayott Thaweethai, Erika B Rosenzweig, James Chan, Lori B Chibnik, Mine S Cicek, Amy J Elliott, Valerie J Flaherman, Andrea S Foulkes, Margot Gage Witvliet, Richard Gallagher, Maria Laura Gennaro, Terry L Jernigan, Elizabeth W Karlson, Stuart D Katz, Patricia A Kinser, Lawrence C Kleinman, Michelle F Lamendola-Essel, Joshua D Milner, Sindhu Mohandas, Praveen C Mudumbi, Jane W Newburger, Kyung E Rhee, Amy L Salisbury, Jessica N Snowden, Cheryl R Stein, Melissa S Stockwell, Kelan G Tantisira, Moriah E Thomason, Dongngan T Truong, David Warburton, John C Wood, Shifa Ahmed, Almary Akerlundh, Akram N Alshawabkeh, Brett R Anderson, Judy L Aschner, Andrew M Atz, Robin L Aupperle, Fiona C Baker, Venkataraman Balaraman, Dithi Banerjee, Deanna M Barch, Arielle Baskin-Sommers, Sultana Bhuiyan, Marie-Abele C Bind, Amanda L Bogie, Tamara Bradford, Natalie C Buchbinder, Elliott Bueler, Hülya Bükülmez, B J Casey, Linda Chang, Maryanne Chrisant, Duncan B Clark, Rebecca G Clifton, Katharine N Clouser, Lesley Cottrell, Kelly Cowan, Viren D'Sa, Mirella Dapretto, Soham Dasgupta, Walter Dehority, Audrey Dionne, Kirsten B Dummer, Matthew D Elias, Shari Esquenazi-Karonika, Danielle N Evans, E Vincent S Faustino, Alexander G Fiks, Daniel Forsha, John J Foxe, Naomi P Friedman, Greta Fry, Sunanda Gaur, Dylan G Gee, Kevin M Gray, Stephanie Handler, Ashraf S Harahsheh, Keren Hasbani, Andrew C Heath, Camden Hebson, Mary M Heitzeg, Christina M Hester, Sophia Hill, Laura Hobart-Porter, Travis K F Hong, Carol R Horowitz, Daniel S Hsia, Matthew Huentelman, Kathy D Hummel, Katherine Irby, Joanna Jacobus, Vanessa L Jacoby, Pei-Ni Jone, David C Kaelber, Tyler J Kasmarcak, Matthew J Kluko, Jessica S Kosut, Angela R Laird, Jeremy Landeo-Gutierrez, Sean M Lang, Christine L Larson, Peter Paul C Lim, Krista M Lisdahl, Brian W McCrindle, Russell J McCulloh, Kimberly McHugh, Alan L Mendelsohn, Torri D Metz, Julie Miller, Elizabeth C Mitchell, Lerraughn M Morgan, Eva M Müller-Oehring, Erica R Nahin, Michael C Neale, Manette Ness-Cochinwala, Sheila M Nolan, Carlos R Oliveira, Onyekachukwu Osakwe, Matthew E Oster, R Mark Payne, Michael A Portman, Hengameh Raissy, Isabelle G Randall, Suchitra Rao, Harrison T Reeder, Johana M Rosas, Mark W Russell, Arash A Sabati, Yamuna Sanil, Alice I Sato, Michael S Schechter, Rangaraj Selvarangan, S Kristen Sexson Tejtel, Divya Shakti, Kavita Sharma, Lindsay M Squeglia, Shubika Srivastava, Michelle D Stevenson, Jacqueline Szmuszkovicz, Maria M Talavera-Barber, Ronald J Teufel, Deepika Thacker, Felicia Trachtenberg, Mmekom M Udosen, Megan R Warner, Sara E Watson, Alan Werzberger, Jordan C Weyer, Marion J Wood, H Shonna Yin, William T Zempsky, Emily Zimmerman, Benard P Dreyer
IMPORTANCE: The prevalence, pathophysiology, and long-term outcomes of COVID-19 (post-acute sequelae of SARS-CoV-2 [PASC] or "Long COVID") in children and young adults remain unknown. Studies must address the urgent need to define PASC, its mechanisms, and potential treatment targets in children and young adults. OBSERVATIONS: We describe the protocol for the Pediatric Observational Cohort Study of the NIH's REsearching COVID to Enhance Recovery (RECOVER) Initiative...
2024: PloS One
#2
JOURNAL ARTICLE
Kim M Pepin, Keith Carlisle, Dean Anderson, Michael G Baker, Richard B Chipman, Jackie Benschop, Nigel P French, Suzie Greenhalgh, Scott McDougall, Petra Muellner, Emil Murphy, Dion R J O'Neale, Michael J Plank, David T S Hayman
One Health recognizes the health of humans, agriculture, wildlife, and the environment are interrelated. The concept has been embraced by international health and environmental authorities such as WHO, WOAH, FAO, and UNEP, but One Health approaches have been more practiced by researchers than national or international authorities. To identify priorities for operationalizing One Health beyond research contexts, we conducted 41 semi-structured interviews with professionals across One Health sectors (public health, environment, agriculture, wildlife) and institutional contexts, who focus on national-scale and international applications...
June 2024: One Health
#3
JOURNAL ARTICLE
Jack E Henningfield, Sean J Belouin, David B Yaden, Julian Urrutia, Brian T Anderson, Ann Berger, Charles S Grob, Beatriz C Labate, Larissa J Maier, M Catherine Maternowska, Frank Weichold, Veronica Magar
No abstract text is available yet for this article.
May 6, 2024: Journal of Psychoactive Drugs
#4
JOURNAL ARTICLE
Kyung E Rhee, Takisha Corbett, Shamin Patel, Dawn M Eichen, David R Strong, Cheryl Anderson, Bess Marcus, Kerri N Boutelle
Family-based behavioral treatment (FBT) is one of the most effective treatments for childhood obesity. These programs include behavior change strategies and basic parenting training to help parents make healthy diet and physical activity changes for their children. While effective, not all families respond to this program. Additional training on how to effectively deliver these behavior change strategies may improve outcomes. The authoritative parenting style is associated with many positive academic and socio-emotional outcomes in children, and is characterized by displays of warmth and support while also being consistent with setting limits and boundaries...
May 2, 2024: Contemporary Clinical Trials
#5
JOURNAL ARTICLE
Jacob A Dillard, Sharon A Taft-Benz, Audrey C Knight, Elizabeth J Anderson, Katia D Pressey, Breantié Parotti, Sabian A Martinez, Jennifer L Diaz, Sanjay Sarkar, Emily A Madden, Gabriela De la Cruz, Lily E Adams, Kenneth H Dinnon, Sarah R Leist, David R Martinez, Alexandra Schäfer, John M Powers, Boyd L Yount, Izabella N Castillo, Noah L Morales, Jane Burdick, Mia Katrina D Evangelista, Lauren M Ralph, Nicholas C Pankow, Colton L Linnertz, Premkumar Lakshmanane, Stephanie A Montgomery, Martin T Ferris, Ralph S Baric, Victoria K Baxter, Mark T Heise
Whole virus-based inactivated SARS-CoV-2 vaccines adjuvanted with aluminum hydroxide have been critical to the COVID-19 pandemic response. Although these vaccines are protective against homologous coronavirus infection, the emergence of novel variants and the presence of large zoonotic reservoirs harboring novel heterologous coronaviruses provide significant opportunities for vaccine breakthrough, which raises the risk of adverse outcomes like vaccine-associated enhanced respiratory disease. Here, we use a female mouse model of coronavirus disease to evaluate inactivated vaccine performance against either homologous challenge with SARS-CoV-2 or heterologous challenge with a bat-derived coronavirus that represents a potential emerging disease threat...
May 3, 2024: Nature Communications
#6
JOURNAL ARTICLE
Nesrine S Rachedi, Ying Tang, Yi-Yin Tai, Jingsi Zhao, Caroline Chauvet, Julien Grynblat, Kouamé Kan Firmin Akoumia, Leonard Estephan, Stéphanie Torrino, Chaima Sbai, Amel Ait-Mouffok, Joseph D Latoche, Yassmin Al Aaraj, Frederic Brau, Sophie Abélanet, Stephan Clavel, Yingze Zhang, Christelle Guillermier, Naveen V G Kumar, Sina Tavakoli, Olaf Mercier, Michael G Risbano, Zhong-Ke Yao, Guangli Yang, Ouathek Ouerfelli, Jason S Lewis, David Montani, Marc Humbert, Matthew L Steinhauser, Carolyn J Anderson, William M Oldham, Frédéric Perros, Thomas Bertero, Stephen Y Chan
Perivascular collagen deposition by activated fibroblasts promotes vascular stiffening and drives cardiovascular diseases such as pulmonary hypertension (PH). Whether and how vascular fibroblasts rewire their metabolism to sustain collagen biosynthesis remains unknown. Here, we found that inflammation, hypoxia, and mechanical stress converge on activating the transcriptional coactivators YAP and TAZ (WWTR1) in pulmonary arterial adventitial fibroblasts (PAAFs). Consequently, YAP and TAZ drive glutamine and serine catabolism to sustain proline and glycine anabolism and promote collagen biosynthesis...
April 24, 2024: Cell Metabolism
#7
REVIEW
Christopher J De Jonge, Christopher L R Barratt, R John Aitken, Richard A Anderson, Peter Baker, David Y L Chan, Mark P Connolly, Michael L Eisenberg, Nicolas Garrido, Niels Jørgensen, Sarah Kimmins, Csilla Krausz, Robert I McLachlan, Craig Niederberger, Moira K O'Bryan, Allan Pacey, Lærke Priskorn, Satu Rautakallio-Hokkanen, Gamal Serour, Joris A Veltman, Donna L Vogel, Mónica H Vazquez-Levin
BACKGROUND: The widespread interest in male reproductive health (MRH), fueled by emerging evidence, such as the global decline in sperm counts, has intensified concerns about the status of MRH. Consequently, there is a pressing requirement for a strategic, systematic approach to identifying critical questions, collecting pertinent information, and utilizing these data to develop evidence-based strategies. The methods for addressing these questions and the pathways toward their answers will inevitably vary based on the variations in cultural, geopolitical, and health-related contexts...
2024: Human Reproduction Open
#8
JOURNAL ARTICLE
Carolyn T Bramante, Kenneth B Beckman, Tanvi Mehta, Amy B Karger, David J Odde, Christopher J Tignanelli, John B Buse, Darrell M Johnson, Ray H B Watson, Jerry J Daniel, David M Liebovitz, Jacinda M Nicklas, Ken Cohen, Michael A Puskarich, Hrishikesh K Belani, Lianne K Siegel, Nichole R Klatt, Blake Anderson, Katrina M Hartman, Via Rao, Aubrey A Hagen, Barkha Patel, Sarah L Fenno, Nandini Avula, Neha V Reddy, Spencer M Erickson, Regina D Fricton, Samuel Lee, Gwendolyn Griffiths, Matthew F Pullen, Jennifer L Thompson, Nancy E Sherwood, Thomas A Murray, Michael R Rose, David R Boulware, Jared D Huling
BACKGROUND: Metformin has antiviral activity against RNA viruses including severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The mechanism appears to be suppression of protein translation via targeting the host mechanistic target of rapamycin pathway. In the COVID-OUT randomized trial for outpatient coronavirus disease 2019 (COVID-19), metformin reduced the odds of hospitalizations/death through 28 days by 58%, of emergency department visits/hospitalizations/death through 14 days by 42%, and of long COVID through 10 months by 42%...
May 1, 2024: Clinical Infectious Diseases
#9
JOURNAL ARTICLE
Adam M Galloway, David J Keene, Anna Anderson, Colin Holton, Anthony C Redmond, Heidi J Siddle, Suzanne Richards, Daniel C Perry
AIMS: The aim of this study was to produce clinical consensus recommendations about the non-surgical treatment of children with Perthes' disease. The recommendations are intended to support clinical practice in a condition for which there is no robust evidence to guide optimal care. METHODS: A two-round, modified Delphi study was conducted online. An advisory group of children's orthopaedic specialists consisting of physiotherapists, surgeons, and clinical nurse specialists designed a survey...
May 1, 2024: Bone & Joint Journal
#10
JOURNAL ARTICLE
Rachel J Anderson, J Helgi Clayton McClure, Emma Bishop, David Howe, Kevin J Riggs, Stephen A Dewhurst
Previous research demonstrating that positive episodic simulation enhances future expectancies has relied on explicit expectancy measures. The current study investigated the effects of episodic simulation on implicit expectancies. Using the Future Thinking Implicit Relational Assessment Procedure (FT-IRAP), participants made true/false decisions to indicate whether or not they expected positive/negative outcomes after adopting orientations consistent or inconsistent with an optimistic disposition. The outcome measure, DIRAP, was based on response time differences between consistent and inconsistent blocks...
2024: PloS One
#11
JOURNAL ARTICLE
Jason E Bloom, Emily Nehme, Elizabeth Davida Paratz, Luke Dawson, Adam J Nelson, Jocasta Ball, Amminadab Eliakundu, Aleksandr Voskoboinik, David Anderson, Stephen Bernard, Aidan Burrell, Andrew A Udy, David Pilcher, Shelley Cox, William Chan, Cathrine Mihalopoulos, David Kaye, Ziad Nehme, Dion Stub
OBJECTIVES: We aimed to assess the healthcare costs and impact on the economy at large arising from emergency medical services (EMS) treated non-traumatic shock. DESIGN: We conducted a population-based cohort study, where EMS-treated patients were individually linked to hospital-wide and state-wide administrative datasets. Direct healthcare costs (Australian dollars, AUD) were estimated for each element of care using a casemix funding method. The impact on productivity was assessed using a Markov state-transition model with a 3-year horizon...
April 28, 2024: BMJ Open
#12
JOURNAL ARTICLE
Andrew R Gamble, Marnee J McKay, David B Anderson, Evangelos Pappas, Ignatius Alvarez Cooper, Sophie Macpherson, Ian A Harris, Stephanie R Filbay, Kirsten McCaffery, Rachel Thompson, Tammy C Hoffmann, Christopher G Maher, Joshua R Zadro
AIM: To develop and user test an evidence-based patient decision aid for children and adolescents who are considering anterior cruciate ligament (ACL) reconstruction. DESIGN: Mixed-methods study describing the development of a patient decision aid. SETTING: A draft decision aid was developed by a multidisciplinary steering group (including various types of health professionals and researchers, and consumers) informed by the best available evidence and existing patient decision aids...
April 29, 2024: BMJ Open
#13
JOURNAL ARTICLE
Abdul Al-Shawwa, Kalum Ost, David Anderson, Newton Cho, Nathan Evaniew, W Bradley Jacobs, Allan R Martin, Ranjeet Gaekwad, Saswati Tripathy, Jacques Bouchard, Steven Casha, Roger Cho, Stephen duPlessis, Peter Lewkonia, Fred Nicholls, Paul T Salo, Alex Soroceanu, Ganesh Swamy, Kenneth C Thomas, Michael M H Yang, Julien Cohen-Adad, David W Cadotte
BACKGROUND CONTEXT: Degenerative cervical myelopathy (DCM) is the most common form of atraumatic spinal cord injury globally. Degeneration of spinal discs, bony osteophyte growth and ligament pathology results in physical compression of the spinal cord contributing to damage of white matter tracts and grey matter cellular populations. This results in an insidious neurological and functional decline in patients which can lead to paralysis. Magnetic resonance imaging (MRI) confirms the diagnosis of DCM and is a prerequisite to surgical intervention, the only known treatment for this disorder...
April 26, 2024: Spine Journal: Official Journal of the North American Spine Society
#14
JOURNAL ARTICLE
Jamie Anderson, Jack S Benton, Junyan Ye, Ellie Barker, Vanessa G Macintyre, Jack Wilkinson, James Rothwell, Matthew Dennis, David P French
There is little robust evidence of how sustainable park interventions impact on physical activity and other behaviours important for wellbeing. This controlled natural experimental study aimed to examine the effects of co-designing a sustainable park intervention, in a deprived UK urban area, on walking and other wellbeing behaviours. Behaviour observations were conducted at two intervention sites and two matched comparison sites (n = 4,783). Walking observations (primary outcome), wellbeing behaviours (vigorous, sedentary, social and take notice activities) and demographic characteristics were assessed at pre-intervention, and post-intervention (3 and 15 months)...
April 21, 2024: Environment International
#15
JOURNAL ARTICLE
Elisabet Ampudia-Mesias, Charles S Cameron, Eunjae Yoo, Marcus Kelly, Sarah M Anderson, Riley Manning, Juan E Abrahante Lloréns, Christopher L Moertel, Hyungshin Yim, David J Odde, Nurten Saydam, Okay Saydam
Medulloblastoma (MB) encompasses diverse subgroups, and leptomeningeal disease/metastasis (LMD) plays a substantial role in associated fatalities. Despite extensive exploration of canonical genes in MB, the molecular mechanisms underlying LMD and the involvement of the orthodenticle homeobox 2 (OTX2) gene, a key driver in aggressive MB Group 3, remain insufficiently understood. Recognizing OTX2's pivotal role, we investigated its potential as a catalyst for aggressive cellular behaviors, including migration, invasion, and metastasis...
April 17, 2024: International Journal of Molecular Sciences
#16
JOURNAL ARTICLE
Mark P Purdue, Diptavo Dutta, Mitchell J Machiela, Bryan R Gorman, Timothy Winter, Dayne Okuhara, Sara Cleland, Aida Ferreiro-Iglesias, Paul Scheet, Aoxing Liu, Chao Wu, Samuel O Antwi, James Larkin, Stênio C Zequi, Maxine Sun, Keiko Hikino, Ali Hajiran, Keith A Lawson, Flavio Cárcano, Odile Blanchet, Brian Shuch, Kenneth G Nepple, Gaëlle Margue, Debasish Sundi, W Ryan Diver, Maria A A K Folgueira, Adrie van Bokhoven, Florencia Neffa, Kevin M Brown, Jonathan N Hofmann, Jongeun Rhee, Meredith Yeager, Nathan R Cole, Belynda D Hicks, Michelle R Manning, Amy A Hutchinson, Nathaniel Rothman, Wen-Yi Huang, W Marston Linehan, Adriana Lori, Matthieu Ferragu, Merzouka Zidane-Marinnes, Sérgio V Serrano, Wesley J Magnabosco, Ana Vilas, Ricardo Decia, Florencia Carusso, Laura S Graham, Kyra Anderson, Mehmet A Bilen, Cletus Arciero, Isabelle Pellegrin, Solène Ricard, Ghislaine Scelo, Rosamonde E Banks, Naveen S Vasudev, Naeem Soomro, Grant D Stewart, Adebanji Adeyoju, Stephen Bromage, David Hrouda, Norma Gibbons, Poulam Patel, Mark Sullivan, Andrew Protheroe, Francesca I Nugent, Michelle J Fournier, Xiaoyu Zhang, Lisa J Martin, Maria Komisarenko, Timothy Eisen, Sonia A Cunningham, Denise C Connolly, Robert G Uzzo, David Zaridze, Anush Mukeria, Ivana Holcatova, Anna Hornakova, Lenka Foretova, Vladimir Janout, Dana Mates, Viorel Jinga, Stefan Rascu, Mirjana Mijuskovic, Slavisa Savic, Sasa Milosavljevic, Valérie Gaborieau, Behnoush Abedi-Ardekani, James McKay, Mattias Johansson, Larry Phouthavongsy, Lindsay Hayman, Jason Li, Ilinca Lungu, Stephania M Bezerra, Aline G Souza, Claudia T G Sares, Rodolfo B Reis, Fabio P Gallucci, Mauricio D Cordeiro, Mark Pomerantz, Gwo-Shu M Lee, Matthew L Freedman, Anhyo Jeong, Samantha E Greenberg, Alejandro Sanchez, R Houston Thompson, Vidit Sharma, David D Thiel, Colleen T Ball, Diego Abreu, Elaine T Lam, William C Nahas, Viraj A Master, Alpa V Patel, Jean-Christophe Bernhard, Neal D Freedman, Pierre Bigot, Rui M Reis, Leandro M Colli, Antonio Finelli, Brandon J Manley, Chikashi Terao, Toni K Choueiri, Dirce M Carraro, Richard Houlston, Jeanette E Eckel-Passow, Philip H Abbosh, Andrea Ganna, Paul Brennan, Jian Gu, Stephen J Chanock
Here, in a multi-ancestry genome-wide association study meta-analysis of kidney cancer (29,020 cases and 835,670 controls), we identified 63 susceptibility regions (50 novel) containing 108 independent risk loci. In analyses stratified by subtype, 52 regions (78 loci) were associated with clear cell renal cell carcinoma (RCC) and 6 regions (7 loci) with papillary RCC. Notably, we report a variant common in African ancestry individuals ( rs7629500 ) in the 3' untranslated region of VHL, nearly tripling clear cell RCC risk (odds ratio 2...
April 26, 2024: Nature Genetics
#17
JOURNAL ARTICLE
Scott T Anderson, Jordan R Mount, Braden C Hintze, Jacob S Hogan, Irving A Jorge, David A Etzioni, Ga-Ram Han, Justin T Brady
INTRODUCTION: Physicians have gravitated toward larger group practice arrangements in recent years. However, consolidation trends in colorectal surgery have yet to be well described. Our objective was to assess current trends in practice consolidation within colorectal surgery and evaluate underlying demographic trends including age, gender, and geography. METHODS: We performed a retrospective cross-sectional study using the Center for Medicare Services National Downloadable File from 2015 to 2022...
April 25, 2024: Journal of Surgical Research
#18
JOURNAL ARTICLE
Ciliopathy patient variants reveal organelle-specific functions for TUBB4B in axonemal microtubules.
Daniel O Dodd, Sabrina Mechaussier, Patricia L Yeyati, Fraser McPhie, Jacob R Anderson, Chen Jing Khoo, Amelia Shoemark, Deepesh K Gupta, Thomas Attard, Maimoona A Zariwala, Marie Legendre, Diana Bracht, Julia Wallmeier, Miao Gui, Mahmoud R Fassad, David A Parry, Peter A Tennant, Alison Meynert, Gabrielle Wheway, Lucas Fares-Taie, Holly A Black, Rana Mitri-Frangieh, Catherine Faucon, Josseline Kaplan, Mitali Patel, Lisa McKie, Roly Megaw, Christos Gatsogiannis, Mai A Mohamed, Stuart Aitken, Philippe Gautier, Finn R Reinholt, Robert A Hirst, Chris O'Callaghan, Ketil Heimdal, Mathieu Bottier, Estelle Escudier, Suzanne Crowley, Maria Descartes, Ethylin W Jabs, Priti Kenia, Jeanne Amiel, Giacomo Maria Bacci, Claudia Calogero, Viviana Palazzo, Lucia Tiberi, Ulrike Blümlein, Andrew Rogers, Jennifer A Wambach, Daniel J Wegner, Anne B Fulton, Margaret Kenna, Margaret Rosenfeld, Ingrid A Holm, Alan Quigley, Emma A Hall, Laura C Murphy, Diane M Cassidy, Alex von Kriegsheim, Jean-François Papon, Laurent Pasquier, Marlène S Murris, James D Chalmers, Claire Hogg, Kenneth A Macleod, Don S Urquhart, Stefan Unger, Timothy J Aitman, Serge Amselem, Margaret W Leigh, Michael R Knowles, Heymut Omran, Hannah M Mitchison, Alan Brown, Joseph A Marsh, Julie P I Welburn, Shih-Chieh Ti, Amjad Horani, Jean-Michel Rozet, Isabelle Perrault, Pleasantine Mill
Tubulin, one of the most abundant cytoskeletal building blocks, has numerous isotypes in metazoans encoded by different conserved genes. Whether these distinct isotypes form cell type- and context-specific microtubule structures is poorly understood. Based on a cohort of 12 patients with primary ciliary dyskinesia as well as mouse mutants, we identified and characterized variants in the TUBB4B isotype that specifically perturbed centriole and cilium biogenesis. Distinct TUBB4B variants differentially affected microtubule dynamics and cilia formation in a dominant-negative manner...
April 26, 2024: Science
#19
JOURNAL ARTICLE
Andreia Vasconcelos, Jonathan D King, Cláudio Nunes-Alves, Roy Anderson, Daniel Argaw, Maria-Gloria Basáñez, Shakir Bilal, David J Blok, Seth Blumberg, Anna Borlase, Oliver J Brady, Raiha Browning, Nakul Chitnis, Luc E Coffeng, Emily H Crowley, Zulma M Cucunubá, Derek A T Cummings, Christopher Neil Davis, Emma Louise Davis, Matthew Dixon, Andrew Dobson, Louise Dyson, Michael French, Claudio Fronterre, Emanuele Giorgi, Ching-I Huang, Saurabh Jain, Ananthu James, Sung Hye Kim, Klodeta Kura, Ana Lucianez, Michael Marks, Pamela Sabina Mbabazi, Graham F Medley, Edwin Michael, Antonio Montresor, Nyamai Mutono, Thumbi S Mwangi, Kat S Rock, Martha-Idalí Saboyá-Díaz, Misaki Sasanami, Markus Schwehm, Simon E F Spencer, Ariktha Srivathsan, Robert S Stawski, Wilma A Stolk, Samuel A Sutherland, Louis-Albert Tchuem Tchuenté, Sake J de Vlas, Martin Walker, Simon J Brooker, T Déirdre Hollingsworth, Anthony W Solomon, Ibrahima Socé Fall
Over the past decade, considerable progress has been made in the control, elimination, and eradication of neglected tropical diseases (NTDs). Despite these advances, most NTD programs have recently experienced important setbacks; for example, NTD interventions were some of the most frequently and severely impacted by service disruptions due to the coronavirus disease 2019 (COVID-19) pandemic. Mathematical modeling can help inform selection of interventions to meet the targets set out in the NTD road map 2021-2030, and such studies should prioritize questions that are relevant for decision-makers, especially those designing, implementing, and evaluating national and subnational programs...
April 25, 2024: Clinical Infectious Diseases
#20
JOURNAL ARTICLE
Lingzhi 灵芝 Wang王, Maokai Hu, Lifan Wang, Yi 轶 Yang 杨, Jiawen Yang, Haley Gomez, Sijie Chen, Lei Hu, Ting-Wan Chen, Jun Mo, Xiaofeng Wang, Dietrich Baade, Peter Hoeflich, J Craig Wheeler, Giuliano Pignata, Jamison Burke, Daichi Hiramatsu, D Andrew Howell, Curtis McCully, Craig Pellegrino, Lluís Galbany, Eric Y Hsiao, David J Sand, Jujia Zhang, Syed A Uddin, J P Anderson, Chris Ashall, Cheng Cheng, Mariusz Gromadzki, Cosimo Inserra, Han Lin, N Morrell, Antonia Morales-Garoffolo, T E Müller-Bravo, Matt Nicholl, Estefania Padilla Gonzalez, M M Phillips, J Pineda-García, Hanna Sai, Mathew Smith, M Shahbandeh, Shubham Srivastav, M D Stritzinger, Sheng Yang, D R Young, Lixin Yu, Xinghan Zhang
Dust associated with various stellar sources in galaxies at all cosmic epochs remains a controversial topic, particularly whether supernovae play an important role in dust production. We report evidence of dust formation in the cold, dense shell behind the ejecta-circumstellar medium (CSM) interaction in the Type Ia-CSM supernova (SN) 2018evt three years after the explosion, characterized by a rise in mid-infrared emission accompanied by an accelerated decline in the optical radiation of the SN. Such a dust-formation picture is also corroborated by the concurrent evolution of the profiles of the Hα emission line...
2024: Nature Astronomy
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