Chariene Shao-Lin Woo, Ronnie Siu-Lun Ho, Grace Ho, Hoi-To Lau, Carol Ho-Yi Fong, Johnny Yau-Cheung Chang, Eunice Ka-Hong Leung, Lawrence Chi-Kin Tang, Ivan Kwok-Ming Ma, Alan Chun-Hong Lee, David Tak-Wai Lui, Yu-Cho Woo, Wing-Sun Chow, Gilberto Ka-Kit Leung, Kathryn Choon-Beng Tan, Karen Siu-Ling Lam, Chi-Ho Lee
BACKGROUND: The 2022 World Health Organization (WHO) classification of pituitary neuroendocrine tumour (PitNET) supersedes the previous one in 2017 and further consolidates the role of transcription factors (TF) in the diagnosis of PitNET. Here, we investigated the clinical utility of the 2022 WHO classification, as compared to that of 2017, in a cohort of patients with non-functioning PitNET (NF-PitNET). METHODS: A total of 113 NF-PitNET patients who underwent resection between 2010 and 2021, and had follow-up at Queen Mary Hospital, Hong Kong, were recruited...
2024: Frontiers in Endocrinology