Carola Buscemi, Cristiana Randazzo, Anna Maria Barile, Roberta Caruso, Piero Colombrita, Martina Lombardo, Piergiorgio Lo Verde, Natalia Sottile, Mario Barbagallo, Silvio Buscemi
BACKGROUND: Endothelial function declines with age and plays a critical role in cardiovascular health. Therefore, investigating endothelial function in successful aging models, such as centenarians, is of interest. Flow-mediated dilation (FMD) of the brachial artery is the gold standard for measuring endothelial function in vivo in humans. Therefore, we investigated, for the first time, the FMD of the brachial artery in a group of healthy centenarians. METHODS: Selected as part of the ABCD project (nutrition, cardiovascular wellness, and diabetes) centenarians (aged ≥100 years) living in the municipalities of Madonie (Palermo, Italy) were compared with a younger (aged <65 years) sex-matched control group from the ABCD general cohort...
May 9, 2024: Experimental Gerontology