Yang Liang Boo, Liang Piu Koh
Mature T- and natural killer (NK)-cell non-Hodgkin lymphoma (T-cell NHL) have a poor prognosis. Data from existing retrospective and prospective studies has suggested that high-dose chemotherapy (HDT) followed by autologous hematopoietic cell transplantation (auto-HCT) may improve the survival in patients with chemosensitive disease, either in the upfront or salvage setting. Auto-HCT is currently recommended to be used as frontline consolidation in peripheral T-cell lymphoma not otherwise specified (PTCL-nos), angioimmunoblastic T-cell lymphoma (AITL), anaplastic large cell lymphoma-anaplastic lymphoma kinase (ALCL-ALK) negative, NK/T-cell (disseminated), and enteropathy-associated T-cell lymphoma (EATL)...
April 12, 2021: Transplantation and cellular therapy
Guillermo Mendez-Rebolledo, Rodrigo Guzmán-Venegas, Oscar Valencia, Kohei Watanabe
Compartmentalization of animal and human skeletal muscle by multiple motor nerve branches known as the neuromuscular compartment (NMC) has been observed primarily in muscles that participate in a plane of motion. In this context, the peroneus longus muscle contributes to eversion and plantarflexion of the ankle and the presence of NMCs has been reported. However, no research has reported the selective activation of the compartments of the peroneus longus during the performance of different ankle movements. The purpose of this research was to determine the contribution of peroneus longus NMCs, through multi-channel surface electromyography (sEMG), to eversion and plantarflexion movements...
2021: PloS One
Anne Fältström, Joanna Kvist, Natalia F N Bittencourt, Luciana D Mendonça, Martin Hägglund
BACKGROUND: The risk of a second anterior cruciate ligament (ACL) injury when participating in pivoting sports after ACL reconstruction is high. Risk factors associated with a second ACL injury are complex. PURPOSE: To investigate the combinations of various clinical risk factors associated with second ACL injury in female soccer players with a primary unilateral ACL reconstruction, using Classification and Regression Tree (CART) analysis. STUDY DESIGN: Cohort study; Level of evidence, 2...
April 15, 2021: American Journal of Sports Medicine
J K Schmidt, J E Debess, L Møller
OBJECTIVES: To primarily assess the existing literature about Magnetic Resonance Therapy (MRT) or Molecular Biophysical Stimulation Therapy (MBST) in the treatment of patients with osteoarthritis (OA). The scoping review question was: What has been reported about MRT or MBST concerning treatment of patients with OA? KEY FINDINGS: The applied treatment program consisted of one hour daily treatment for patients in all the included studies. In terms of duration of treatment, four studies suggested treatment for nine consecutive days, two for five days and one study reported treatment on weekdays for two weeks...
April 11, 2021: Radiography
Indranil Kushare, Nicole Wunderlich, Ahmed Elabd, Elsayed Attia
PURPOSE: Lisfranc fracture dislocations are rare injuries and even more so in the pediatric population. The main purpose of our study is to present a descriptive analysis of Lisfranc injuries in pediatric patients to add to the current sparse literature on this topic. In addition, our secondary outcome was to analyze any differences in patients treated conservatively versus operatively, and those with isolated Lisfranc injuries versus those with associated foot injuries. METHODS: Charts of patients with Lisfranc injury treated at a tertiary pediatric hospital from January 2010 to July 2019 were reviewed to analyze their demographics, injury characteristics, management details and rehabilitation protocol...
March 2021: Foot
Chuchu Churko, Mekuria Asnakew Asfaw, Abayneh Tunje, Eyayou Girma, Zerihun Zerdo
BACKGROUND: Podoconiosis is entirely preventable, non-communicable disease with high potential of elimination. The prevalence of podoconiosis in Ethiopia was 7.45%. One of the pillars for elimination of podoconiosis is morbidity control and management. Therefore, the present study aimed to assess the knowledge, attitude, practices and associated factors of health professionals towards podoconiosis cause, prevention and treatments. METHODS: Facility based cross-sectional study was conducted...
April 14, 2021: Journal of Foot and Ankle Research
Young Hwan Park, Woon Kim, Jung Woo Choi, Hak Jun Kim
OBJECTIVE: Identifying the risk factors for persistent pain despite proper conservative treatment in adult symptomatic accessory navicular may reduce the need for surgical treatment. The aim of this study was to identify any such risk factors. DESIGN: Cohort study. SETTING: University hospital foot and ankle clinic. PATIENTS: A retrospective review of 313 patients who presented with adult symptomatic accessory navicular was performed...
March 1, 2021: Clinical Journal of Sport Medicine
(no author information available yet)
No abstract text is available yet for this article.
January 2021: Journal of ISAKOS
Florian Jungmann, B Kämpgen, F Hahn, D Wagner, P Mildenberger, C Düber, R Kloeckner
OBJECTIVE: During the COVID-19 pandemic, the number of patients presenting in hospitals because of emergency conditions decreased. Radiology is thus confronted with the effects of the pandemic. The aim of this study was to use natural language processing (NLP) to automatically analyze the number and distribution of fractures during the pandemic and in the 5 years before the pandemic. MATERIALS AND METHODS: We used a pre-trained commercially available NLP engine to automatically categorize 5397 radiological reports of radiographs (hand/wrist, elbow, shoulder, ankle, knee, pelvis/hip) within a 6-week period from March to April in 2015-2020 into "fracture affirmed" or "fracture not affirmed...
April 13, 2021: Skeletal Radiology
Marie-Philippe Mercier, Virginie Blanchette, Vincent Cantin, Magali Brousseau-Foley
BACKGROUND: An intractable plantar keratoma (IPK) is a conical thickening of the epidermis' stratum corneum and a common cause of foot pain which can have a significant, detrimental impact on the mobility, quality of life and independence of individuals. Conservative treatments are currently offered to patients with IPK, but they are unsatisfactory since they do not offer a sufficient or permanent reduction of symptoms. The purpose of this study was the evaluation of the feasibility, safety and effectiveness of innovative treatments for intractable plantar keratoma (IPK)...
April 13, 2021: Journal of Foot and Ankle Research
Heri Kristianto, Agung Waluyo, Dewi Gayatri
This research aims to analyze the relationship between diabetic foot ulcers profile and ankle brachial index (ABI) score. This quantitative research employed descriptive design with cross sectional method. 76 patients with diabetic foot ulcers were recruited purposively at three hospitals in Malang, Indonesia. The data collection includes patient characteristics; measurement of ABI score with foot Doppler device; measurements of granulation, necrosis, fibrin, and wound with the MowA. Data were analyzed using Pearson and Spearman correlation tests...
April 2021: Enfermería Clínica
Youngju Shin, So Young Ahn, Soo-Kyung Bok
Objective: To investigate differences in the relative sizes of the ankle-stabilizing muscles in individuals with versus without flexible flat feet and to determine predictors of symptom severity. Methods: This cross-sectional study included 30 patients with symptomatic flexible flat feet and 24 normal controls. The following were evaluated: foot posture index, resting calcaneal stance position angle, radiographic findings (calcaneal pitch, Meary's angle, talocalcaneal angle, talonavicular coverage angle [TNCA]), foot function index (FFI), and cross-sectional areas (CSA) of the tibialis anterior (TA), tibialis posterior (TP), and peroneus longus (PL) upon ultrasonographic examination...
April 14, 2021: Annals of Rehabilitation Medicine
Kyoung-Ha Park, Woo Jung Park, Hyun-Sook Kim, Sang Ho Jo, Sung-Ai Kim, Hong-Mi Choi, Sang Won Suh
BACKGROUND: Endothelial dysfunction is a predictor of atherosclerotic cardiovascular disease (ASCVD) and plays an important role in vasospastic angina (VA). OBJECTIVES: This study evaluated whether flow-mediated dilation (FMD) is also a good marker of 10-year ASCVD risk (10Y-ASCVDR) in patients with VA. METHODS: Based on their clinical history and coronary artery diameter stenosis (DS), patients were retrospectively enrolled into VA (DS <50% and positive ergonovine provocation), minor coronary artery disease (mCAD, DS <30%), and significant coronary artery disease (sCAD, DS ≥50%) groups...
April 13, 2021: Cardiology
Ingrid Skaaret, Harald Steen, Sanyalak Niratisairak, David Swanson, Inger Holm
BACKGROUND: Children with cerebral palsy often have problems to support the body centre of mass, seen as increased ratio between excessive vertical ground reaction forces during weight acceptance and decreased forces below bodyweight in late stance. We aimed to examine whether increasing ankle range of motion through surgery and restraining motion with ankle-foot orthoses postoperatively would have impact on the vertical ground reaction force in weight acceptance and late stance. METHODS: Ground reaction forces were recorded from 24 children with bilateral and 32 children with unilateral cerebral palsy, each measured walking barefoot before and after triceps surae lengthening...
March 23, 2021: Clinical Biomechanics
Ferdi Dırvar, Sevda Uzun Dırvar, Mehmet Akif Kaygusuz, Bilge Evren, İrfan Öztürk
OBJECTIVE: This study aimed to investigate the malpractice claims experienced by orthopedic and traumatology physicians and to determine their effects on burnout, job satisfaction, and clinical practice. METHODS: A questionnaire survey was conducted on orthopedic and traumatology specialists between May 2019 and February 2020. Data collection was carried out via e-survey at "turk-ortopedi" mail group, which is an electronic communication network of orthopedic and traumatology physicians...
March 2021: Acta Orthopaedica et Traumatologica Turcica
(no author information available yet)
No abstract text is available yet for this article.
April 13, 2021: Foot & Ankle Specialist
Akira Taniguchi, Shannon F Alejandro, Justin M Kane, Yahya Daoud, Yasuhito Tanaka, Samuel E Ford, James W Brodsky
BACKGROUND: Although it is a widely accepted clinical principle that cavovarus deformity predisposes to peroneal tendon problems, there are limited data to support that assumption. This study tested the hypothesis that cavovarus is associated with peroneal tendon tears and evaluated which radiographic measures correlated with that association. METHODS: A retrospective comparison of radiographic measures of cavovarus in 234 consecutive patients operatively treated for chronically symptomatic peroneal tendon tears was compared to a matched control group...
April 13, 2021: Foot & Ankle International
Wen Guo, Xiaona Li, Juan Wu, Wenfang Zhu, Jing Lu, Pei Qin, Qingqing Diao, Nainzhen Xu, Qun Zhang
BACKGROUND: Serum alkaline phosphatase (ALP) has been recognized as a biomarker of cardiovascular disease (CVD) risk, recently. This study aimed to explore the association of ALP with arterial stiffness and 10-year CVD risk. METHODS: A total of 12 539 participants without CVD who underwent health examinations including serum ALP level were retrospectively analysed. Arterial stiffness was measured by brachial-ankle pulse wave velocity (baPWV), and 10-year CVD risk was evaluated by Framingham risk score...
April 13, 2021: European Journal of Clinical Investigation
Karin Schöls
A 30-year-old woman presented with remitting upper airway infections. Over time she developed mastoiditis resistant to antibiotics, arthritis of her ankle as well as multilocular arthralgias and a livid discoloration of her fingertips. A computed tomography (CT) scan of her chest revealed a cavernous process and c‑ANCA (Anti Neutrophilen Cytoplasmatic Antibody) positivity led to the diagnosis granulomatosis with polyangiitis (formerly called Wegener's). In line with literature reports, rituximab and cortisosteroid therapy quickly induced remission...
April 8, 2021: Rheuma Plus
Jes S Lindholt, Rikke Søgaard
OBJECTIVE: Although screening for peripheral arterial disease (PAD) seems obvious due to its two to three times increased mortality, high prevalence in the elderly, ease of detection, and relatively harmless prevention, the evidence is sparse. METHODS: A Markov decision model was created to model the lifetime effectiveness and cost effectiveness of general population PAD screening and relevant intervention in 65 year old men. The model was informed by original estimates from the VIVA trial data except for ankle brachial systolic blood pressure index test accuracy, quality of life, and background mortality, which were adopted from the literature...
April 9, 2021: European Journal of Vascular and Endovascular Surgery
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