keyword
https://read.qxmd.com/read/38701539/mesenchymal-stem-cell-derived-exosomes-for-management-of-prostate-cancer-an-updated-view
#1
REVIEW
Fahimeh Lavi Arab, Akram Hoseinzadeh, Fatemeh Hafizi, Fatemeh Sadat Mohammadi, Farid Zeynali, Melika Hadad Tehran, Amirreza Rostami
Prostate cancer represents the second most prevalent form of cancer found in males, and stands as the fifth primary contributor to cancer-induced mortality on a global scale. Research has shown that transplanted mesenchymal stem cells (MSCs) can migrate by homing to tumor sites in the body. In prostate cancer, researchers have explored the fact that MSC-based therapies (including genetically modified delivery vehicles or vectors) and MSC-derived exosomes are emerging as attractive options to improve the efficacy and safety of traditional cancer therapies...
May 2, 2024: International Immunopharmacology
https://read.qxmd.com/read/38701472/slow-fatigue-and-highly-delayed-yielding-via-shear-banding-in-oscillatory-shear
#2
JOURNAL ARTICLE
James O Cochran, Grace L Callaghan, Miles J G Caven, Suzanne M Fielding
We study theoretically the dynamical process of yielding in cyclically sheared amorphous materials, within a thermal elastoplastic model and the soft glassy rheology model. Within both models we find an initially slow accumulation, over many cycles after the inception of shear, of low levels of damage in the form strain heterogeneity across the sample. This slow fatigue then suddenly gives way to catastrophic yielding and material failure. Strong strain localization in the form of shear banding is key to the failure mechanism...
April 19, 2024: Physical Review Letters
https://read.qxmd.com/read/38701471/carrollian-fluids-and-spontaneous-breaking-of-boost-symmetry
#3
JOURNAL ARTICLE
Jay Armas, Emil Have
In the hydrodynamic regime, field theories typically have their boost symmetry spontaneously broken due to the presence of a thermal rest frame although the associated Goldstone field does not acquire independent dynamics. We show that this is not the case for Carrollian field theories where the boost Goldstone field plays a central role. This allows us to give a first-principles derivation of the equilibrium currents and dissipative effects of Carrollian fluids. We also demonstrate that the limit of vanishing speed of light of relativistic fluids is a special case of this class of Carrollian fluids...
April 19, 2024: Physical Review Letters
https://read.qxmd.com/read/38701462/many-body-dynamics-in-monitored-atomic-gases-without-postselection-barrier
#4
JOURNAL ARTICLE
Gianluca Passarelli, Xhek Turkeshi, Angelo Russomanno, Procolo Lucignano, Marco Schirò, Rosario Fazio
We study the properties of a monitored ensemble of atoms driven by a laser field and in the presence of collective decay. The properties of the quantum trajectories describing the atomic cloud drastically depend on the monitoring protocol and are distinct from those of the average density matrix. By varying the strength of the external drive, a measurement-induced phase transition occurs separating two phases with entanglement entropy scaling subextensively with the system size. Incidentally, the critical point coincides with the superradiance transition of the trajectory-averaged dynamics...
April 19, 2024: Physical Review Letters
https://read.qxmd.com/read/38701460/observation-of-skewed-electromagnetic-wakefields-in-an-asymmetric-structure-driven-by-flat-electron-bunches
#5
JOURNAL ARTICLE
W Lynn, T Xu, G Andonian, D S Doran, G Ha, N Majernik, P Piot, J Power, J B Rosenzweig, C Whiteford, E Wisniewski
Relativistic charged-particle beams that generate intense longitudinal fields in accelerating structures also inherently couple to transverse modes. The effects of this coupling may lead to beam breakup instability and thus must be countered to preserve beam quality in applications such as linear colliders. Beams with highly asymmetric transverse sizes (flat beams) have been shown to suppress the initial instability in slab-symmetric structures. However, as the coupling to transverse modes remains, this solution serves only to delay instability...
April 19, 2024: Physical Review Letters
https://read.qxmd.com/read/38701455/precision-measurement-of-the-n-2-triplet-p-j-1-to-j-0-fine-structure-of-atomic-helium-using-frequency-offset-separated-oscillatory-fields
#6
JOURNAL ARTICLE
F Heydarizadmotlagh, T D G Skinner, K Kato, M C George, E A Hessels
Increasing accuracy of the theory and experiment of the n=2 ^{3}P fine structure of helium has allowed for increasingly precise tests of quantum electrodynamics (QED), determinations of the fine-structure constant α, and limitations on possible beyond the standard model physics. Here we present a 2 ppb measurement of the J=1 to J=0 interval. The measurement is performed using frequency-offset separated-oscillatory fields. Our result of 29 616 955 018(60) Hz represents a landmark for helium fine-structure measurements, and, for the first time, will allow for a 1-ppb determination of the fine-structure constant when QED theory for the interval is improved...
April 19, 2024: Physical Review Letters
https://read.qxmd.com/read/38701449/parent-hamiltonian-reconstruction-via-inverse-quantum-annealing
#7
JOURNAL ARTICLE
Davide Rattacaso, Gianluca Passarelli, Angelo Russomanno, Procolo Lucignano, Giuseppe E Santoro, Rosario Fazio
Finding a local Hamiltonian H[over ^] that has a given many-body wave function |ψ⟩ as its ground state, i.e., a parent Hamiltonian, is a challenge of fundamental importance in quantum technologies. Here we introduce a numerical method, inspired by quantum annealing, that efficiently performs this task through an artificial inverse dynamics: a slow deformation of the states |ψ(λ(t))⟩, starting from a simple state |ψ_{0}⟩ with a known H[over ^]_{0}, generates an adiabatic evolution of the corresponding Hamiltonian...
April 19, 2024: Physical Review Letters
https://read.qxmd.com/read/38701447/stark-many-body-localization-in-interacting-infinite-dimensional-systems
#8
JOURNAL ARTICLE
Hristiana Atanasova, André Erpenbeck, Emanuel Gull, Yevgeny Bar Lev, Guy Cohen
We study bulk particle transport in a Fermi-Hubbard model on an infinite-dimensional Bethe lattice, driven by a constant electric field. Previous numerical studies showed that one dimensional analogs of this system exhibit a breakdown of diffusion due to Stark many-body localization at least up to time that scales exponentially with the system size. Here, we consider systems initially in a spin density wave state using a combination of numerically exact and approximate techniques. We show that for sufficiently weak electric fields, the wave's momentum component decays exponentially with time in a way consistent with normal diffusion...
April 19, 2024: Physical Review Letters
https://read.qxmd.com/read/38701446/denoising-and-extension-of-response-functions-in-the-time-domain
#9
JOURNAL ARTICLE
Alexander F Kemper, Chao Yang, Emanuel Gull
Response functions of quantum systems, such as electron Green's functions, magnetic, or charge susceptibilities, describe the response of a system to an external perturbation. They are the central objects of interest in field theories and quantum computing and measured directly in experiment. Response functions are intrinsically causal. In equilibrium and steady-state systems, they correspond to a positive spectral function in the frequency domain. Since response functions define an inner product on a Hilbert space and thereby induce a positive definite function, the properties of this function can be used to reduce noise in measured data and, in equilibrium and steady state, to construct positive definite extensions for data known on finite time intervals, which are then guaranteed to correspond to positive spectra...
April 19, 2024: Physical Review Letters
https://read.qxmd.com/read/38701445/massive-strings-from-a-field-theory-with-ghosts
#10
JOURNAL ARTICLE
Nicholas Carabine, Renann Lipinski Jusinskas
In this Letter, we present the α^{'}-exact background equations of motion of the bosonic chiral string (also known as Hohm-Siegel-Zwiebach model), with the spin-two ghost fields integrated out. This is the first instance of a world sheet model in which all corrections are fully determined in a generic curved spacetime. As a concrete cross-check, we find complete agreement between all three-point and a sample of four-point tree-level scattering amplitudes computed using field theory methods and the chiral string prescription...
April 19, 2024: Physical Review Letters
https://read.qxmd.com/read/38701432/acceptability-of-racial-microaggressions-from-the-perspective-of-speech-language-pathology-students
#11
JOURNAL ARTICLE
Geoffrey A Coalson, Skyller Castello, Kia N Johnson, Janna B Oetting, Eileen Haebig
PURPOSE: Implicit racial and ethnic biases have been documented across a variety of allied health professions; however, minimal research on this topic has been conducted within the field of speech-language pathology. The purpose of this study was to understand implicit racial and ethnic bias in speech-language pathology students by examining their perceptions and attitudes about the acceptability of racial and ethnic microaggressions. We also examined whether the student ratings varied by their racial and ethnic identity (White vs...
May 3, 2024: Language, Speech, and Hearing Services in Schools
https://read.qxmd.com/read/38701383/gelma-based-hydrogel-biomaterial-scaffold-a-versatile-platform-for-regenerative-endodontics
#12
REVIEW
Lei Huang, Xuan Chen, XiaoXia Yang, Yinchun Zhang, Xiaoling Qiu
Endodontic therapy, while generally successful, is primarily limited to mature teeth, hence the pressing need to explore regenerative approaches. Gelatin methacryloyl (GelMA) hydrogels have emerged as pivotal biomaterials, promising a bright future for dental pulp regeneration. Despite advancements in tissue engineering and biomaterials, achieving true pulp tissue regeneration remains a formidable task. GelMA stands out for its injectability, rapid gelation, and excellent biocompatibility, serving as the cornerstone of scaffold materials...
May 2024: Journal of Biomedical Materials Research. Part B, Applied Biomaterials
https://read.qxmd.com/read/38701372/photofunctional-gold-nanocluster-composites-for-bioapplications
#13
REVIEW
Yujie Cong, Jiaren Liu, Jingkai Zhang, Jiaxi Wang, Xiaoyu Wang, Lidong Li
Gold nanoclusters (AuNCs), with customized structures and diverse optical properties, are promising optical materials. Constructing composite systems by the assembly and incorporation of AuNCs can utilize their optical properties to achieve diagnostic and therapeutic applications in the biological field. Therefore, the exploration of the assembly behaviors of AuNCs and the enhancement of their performance has attracted widespread interest. In this review, we introduce multiple interactions and assembly modes that are prevalent in nanocomposites and microcomposites based on AuNCs...
May 3, 2024: ACS Applied Bio Materials
https://read.qxmd.com/read/38701367/electron-imaging-of-nanoscale-charge-distributions-induced-by-femtosecond-light-pulses
#14
JOURNAL ARTICLE
Jonathan T Weber, Sascha Schäfer
Surface charging is ubiquitously observable during in situ transmission electron microscopy of nonconducting specimens as a result of electron beam/sample interactions or optical stimuli and often limits the achievable image stability and spatial or spectral resolution. Here, we report on the electron-optical imaging of surface charging on a nanostructured surface following femtosecond multiphoton photoemission. By quantitatively extracting the light-induced electrostatic potential and studying the charging dynamics on relevant time scales, we gain insights into the details of the multiphoton photoemission process in the presence of an electrostatic background field...
May 3, 2024: Nano Letters
https://read.qxmd.com/read/38701366/maternal-fetal-exposure-to-antibiotics-levels-mother-to-child-transmission-and-potential-health-risks
#15
REVIEW
Shiyu Miao, Jia Yin, Shuang Liu, Qingqing Zhu, Chunyang Liao, Guibin Jiang
Due to its widespread applications in various fields, antibiotics are continuously released into the environment and ultimately enter the human body through diverse routes. Meanwhile, the unreasonable use of antibiotics can also lead to a series of adverse outcomes. Pregnant women and developing fetuses are more susceptible to the influence of external chemicals than adults. The evaluation of antibiotic exposure levels through questionnaire surveys or prescriptions in medical records and biomonitoring-based data shows that antibiotics are frequently prescribed and used by pregnant women around the world...
May 3, 2024: Environmental Science & Technology
https://read.qxmd.com/read/38701352/quantum-equation-of-motion-with-orbital-optimization-for-computing-molecular-properties-in-near-term-quantum-computing
#16
JOURNAL ARTICLE
Phillip W K Jensen, Erik Rosendahl Kjellgren, Peter Reinholdt, Karl Michael Ziems, Sonia Coriani, Jacob Kongsted, Stephan P A Sauer
Determining the properties of molecules and materials is one of the premier applications of quantum computing. A major question in the field is how to use imperfect near-term quantum computers to solve problems of practical value. Inspired by the recently developed variants of the quantum counterpart of the equation-of-motion (qEOM) approach and the orbital-optimized variational quantum eigensolver (oo-VQE), we present a quantum algorithm (oo-VQE-qEOM) for the calculation of molecular properties by computing expectation values on a quantum computer...
May 3, 2024: Journal of Chemical Theory and Computation
https://read.qxmd.com/read/38701336/room-temperature-synthesis-and-low-thermal-conductivity-in-nanocrystalline-ag-3-cus-2
#17
JOURNAL ARTICLE
Anil Kumar B M, Debattam Sarkar, Satya N Guin
Noble-metal-based chalcogenide materials recently gained massive attention in the field of thermoelectrics. In most cases, materials are synthesized using (i) high-temperature solid-state reactions or (ii) soft chemical methods where temperature requirements are lower than those of solid-state reactions (generally below 400 °C). Herein, we present a simple, surfactant-free, room-temperature, and energy-efficient synthesis of Ag3 CuS2 nanocrystals. The present synthesis technique is scalable and capable of gram-scale production...
May 3, 2024: Inorganic Chemistry
https://read.qxmd.com/read/38701258/a-bibliometric-and-visual-analysis-of-research-trends-and-hotspots-of-familial-hypertrophic-cardiomyopathy-a-review
#18
REVIEW
Cong Chen, Yang Liu, Songwei Yang, Ming Chen, Jing Liao
Familial hypertrophic cardiomyopathy (FHCM) is an inherited cardiac disease caused by mutations of sarcomere proteins and can be the underlining substrate for major cardiovascular events. Early identification and diagnosis of FHCM are essential to reduce sudden cardiac death. So, this paper summarized the current knowledge on FHCM, and displayed the analysis via bibliometrics method. The relevant literature on FHCM were screened searched via the Web of Science Core Collection database from 2012 to 2022. The literatures were was summarized and analyzed via the bibliometrics method analyzed via CiteSpace and VOSviewer according to topic categories, distribution of spatiotemporal omics and authors, as well as references...
May 3, 2024: Medicine (Baltimore)
https://read.qxmd.com/read/38701253/research-hotspots-and-trends-of-complementary-and-alternative-therapy-for-neuropathic-pain-a-bibliometric-analysis
#19
JOURNAL ARTICLE
Shilin Wang, Yuanzheng Sun, Huixie Zhao, Yingying Li, Xiaoxin Wang, Qitong Zhang, Xiao-Jie Ren, Yong-Peng Mi
BACKGROUND: Neuropathic pain (NP) is a common type of pain in clinic. Due to the limited effect of drug treatment, many patients with NP are still troubled by this disease. In recent years, complementary and alternative therapy (CAT) has shown good efficacy in the treatment of NP. As the interest in CAT for NP continues to grow, we conducted a bibliometric study of publications on CAT treatment for NP. The aim of this study is to analyze the development overview, research hotspots and future trends in the field of CAT and NP through bibliometric methodology, so as to provide a reference for subsequent researchers...
May 3, 2024: Medicine (Baltimore)
https://read.qxmd.com/read/38701230/experimental-study-on-energy-free-superhydrophobic-radiative-cooling-versatile-film-with-enhanced-environmental-tolerance
#20
JOURNAL ARTICLE
Shijin Nie, Lizhan Bai, Guiping Lin, Kang Yuan, Jingwei Fu, Yunfei Zhang, Huanfa Wang, Hongxiang Lan, Peng Liu, Xinyu Tan, Xinyi Li
Clean, energy-free methods of cooling are an effective way to respond to the global energy crisis. To date, cooling materials using passive daytime radiative cooling (RC) technology have been applied in the fields of energy-efficient buildings, solar photovoltaic cooling, and insulating textiles. However, RC materials frequently suffer from comprehensive damage to their microstructure, resulting in the loss of their initial cooling effect in complex outdoor environments. Here, a superhydrophobic daytime passive RC porous film with environmental tolerance (SRCP film) was fabricated, which integrated strong solar reflectivity (approximately 90%), mid-infrared emissivity (approximately 0...
May 3, 2024: ACS Applied Materials & Interfaces
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