Abbas Ahmadi, Soudabeh Hosseini, Akbar Dorgalaleh, Saeed Hassani, Shadi Tabibian, Behnaz Tavasoli, Ashkan Shabannezhad, Mahdi Taheri, Mahmood Shams
BACKGROUND: β-thalassemia is a group of inherited blood disorders that affect the production of β-globin chains, leading to the reduction or absence of these chains. One of the complications observed in patients with β-thalassemia major (β-TM) is thrombosis, especially in those who receive frequent blood transfusions. This may be due to a decrease in the levels of the natural anticoagulants: protein C (PC), total protein S (PS), and antithrombin (AT). METHODS: In this case-control study, patients with β-TM, who had received at least 20 packed cell transfusions during their lifetime, were included...
April 2024: Journal of Hematology (Brossard, Quebec)