Bruna Eduarda Gandra de Oliveira, Fernanda Latorre Melgaço Maia, Lívia Contini Massimino, Claudio Fernandes Garcia, Ana Maria de Guzzi Plepis, Virgínia da Conceição Amaro Martins, Carlos Henrique Bertoni Reis, Vinícius Rodrigues Silva, Andre Alves Bezerra, Carolina Chen Pauris, Daniela Vieira Buchaim, Yggor Biloria E Silva, Rogerio Leone Buchaim, Marcelo Rodrigues da Cunha
Severe loss of bone mass may require grafting, and, among the alternatives available, there are natural biomaterials that can act as scaffolds for the cell growth necessary for tissue regeneration. Collagen and elastin polymers are a good alternative due to their biomimetic properties of bone tissue, and their characteristics can be improved with the addition of polysaccharides such as chitosan and bioactive compounds such as jatoba resin and pomegranate extract due to their antigenic actions. The aim of this experimental protocol was to evaluate bone neoformation in experimentally made defects in the mandible of rats using polymeric scaffolds with plant extracts added...
April 2, 2024: Pharmaceutics