Peijun Xie, Xingyu Zhou, Yifan Li, Jing Wu, Hanping Zhang, Yu Huang, Xunmin Tan, Lu Wen, Oluwatayo Israel Olasunkanmi, Jingjing Zhou, Zuoli Sun, Min Liu, Guofu Zhang, Ying Wang, Peng Xie, Jian Yang, Peng Zheng
Major depressive disorder (MDD) is a serious mental illness, characterized by disturbances of gut microbiome, it is required to further explore how the carbohydrate-active enzymes (CAZymes) were changed in MDD. Here, using the metagenomic data from patients with MDD (n = 118) and heath controls (HC, n = 118), we found that the whole CAZymes signatures of MDD were significantly discriminated from that in HC. α-diversity indexes of the two groups were also significantly different...
March 5, 2024: Translational Psychiatry