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JOURNAL ARTICLE
Andrew I Efimov, Timothy J Hibberd, Yue Wang, Mingzheng Wu, Kaiqing Zhang, Kaila Ting, Surabhi Madhvapathy, Min-Kyu Lee, Joohee Kim, Jiheon Kang, Mohammad Riahi, Haohui Zhang, Lee Travis, Emily J Govier, Lianye Yang, Nigel Kelly, Yonggang Huang, Abraham Vázquez-Guardado, Nick J Spencer, John A Rogers
Wireless activation of the enteric nervous system (ENS) in freely moving animals with implantable optogenetic devices offers a unique and exciting opportunity to selectively control gastrointestinal (GI) transit in vivo, including the gut-brain axis. Programmed delivery of light to targeted locations in the GI-tract, however, poses many challenges not encountered within the central nervous system (CNS). We report here the development of a fully implantable, battery-free wireless device specifically designed for optogenetic control of the GI-tract, capable of generating sufficient light over large areas to robustly activate the ENS, potently inducing colonic motility ex vivo and increased propulsion in vivo...
April 16, 2024: Biosensors & Bioelectronics
#2
JOURNAL ARTICLE
Jutharat Sukonthachat, Theeraporn Bubpamala, Rungtiva P Poo-Arporn, Pitirat Pholpabu
Due to antimicrobial resistance that occurs throughout the world, antibiotic-releasing hydrogel with at least two drugs that synergistically treat stubborn bacteria is preferable for infection prevention. Hydrogel can serve as a drug reservoir to gradually release drugs in a therapeutic window to effectively treat microorganisms with minimal side effects. The study and development of drug releasing hydrogels requires a reliable, straightforward, cost-effective, fast, and low labor-intensive drug detection technique...
April 21, 2024: Journal of Pharmaceutical and Biomedical Analysis
#3
JOURNAL ARTICLE
Jose Danilo Bengzon Diestro, Nimer Adeeb, Basel Musmar, Hamza Salim, Assala Aslan, Nicole M Cancelliere, Rachel M McLellan, Oktay Algin, Sherief Ghozy, Sovann V Lay, Adrien Guenego, Leonardo Renieri, Joseph Carnevale, Guillaume Saliou, Panagiotis Mastorakos, Kareem El Naamani, Eimad Shotar, Kevin Premat, Markus Möhlenbruch, Michael Kral, Joshua D Bernstock, Omer Doron, Charlotte Chung, Mohamed M Salem, Ivan Lylyk, Paul M Foreman, Jay A Vachhani, Hamza Shaikh, Vedran Župančić, Muhammad U Hafeez, Joshua Catapano, Muhammad Waqas, Mohamed K Ibrahim, Marwa A Mohammed, Cetin Imamoglu, Ahmet Bayrak, James D Rabinov, Yifan Ren, Clemens M Schirmer, Mariangela Piano, Anna L Kühn, Caterina Michelozzi, Stéphanie Elens, Robert M Starke, Ameer E Hassan, Mark Ogilvie, Anh Nguyen, Jesse Jones, Waleed Brinjikji, Marie T Nawka, Marios Psychogios, Christian Ulfert, Bryan Pukenas, Jan-Karl Burkhardt, Thien Huynh, Juan Carlos Martinez-Gutierrez, Muhammed Amir Essibayi, Sunil A Sheth, Gary Spiegel, Rabih G Tawk, Boris Lubicz, Pietro Panni, Ajit S Puri, Guglielmo Pero, Erez Nossek, Eytan Raz, Monika Killer-Oberpfalzer, Christoph J Griessenauer, Hamed Asadi, Adnan Siddiqui, Allan L Brook, David Altschul, Julian Spears, Thomas R Marotta, Andrew F Ducruet, Felipe C Albuquerque, Robert W Regenhardt, Christopher J Stapleton, Peter Kan, Vladimir Kalousek, Pedro Lylyk, Srikanth Boddu, Jared Knopman, Mohammad A Aziz-Sultan, Stavropoula I Tjoumakaris, Pascal M Jabbour, Frédéric Clarençon, Nicola Limbucci, Hugo H Cuellar-Saenz, Vitor Mendes Pereira, Aman B Patel, Adam A Dmytriw
OBJECTIVE: This study was conducted to investigate the impact of antiplatelet administration in the periprocedural period on the occurrence of thromboembolic complications (TECs) in patients undergoing treatment using the Woven EndoBridge (WEB) device for intracranial wide-necked bifurcation aneurysms. The primary objective was to assess whether the use of antiplatelets in the pre- and postprocedural phases reduces the likelihood of developing TECs, considering various covariates. METHODS: A retrospective multicenter observational study was conducted within the WorldWideWEB Consortium and comprised 38 academic centers with endovascular treatment capabilities...
May 3, 2024: Journal of Neurosurgery
#4
JOURNAL ARTICLE
Nan Yan, Yang Cao, Zhiwen Jin, Yucheng Liu, Shengzhong Frank Liu, Zhimin Fang, Jiangshan Feng
Functional agents have been verified to efficiently enhance device performance of perovskite solar cells (PSCs) through surface engineering. However, the influence of intrinsic characteristics of molecules on final device performance has been overlooked. Here, we develop a surface reconstruction strategy to enhance the efficiency of inverted PSCs by mitigating the adverse effects of lead chelation (LC) molecules. We choose bathocuproine (BCP), as the representative of LC molecules for its easy accessibility and outstanding optoelectronic properties...
May 3, 2024: Advanced Materials
#5
JOURNAL ARTICLE
Cunyuan Jiang, Matteo Baggioli, Qing-Dong Jiang
Twisted bilayer graphene (TBG) is a recently discovered two-dimensional superlattice structure which exhibits strongly correlated quantum many-body physics, including strange metallic behavior and unconventional superconductivity. Most of TBG exotic properties are connected to the emergence of a pair of isolated and topological flat electronic bands at the so-called magic angle, θ≈1.05°, which are nevertheless very fragile. In this work, we show that, by employing chiral optical cavities, the topological flat bands can be stabilized away from the magic angle in an interval of approximately 0...
April 19, 2024: Physical Review Letters
#6
JOURNAL ARTICLE
Yu Guo, Zixuan Liu, Hao Tang, Xiao-Min Hu, Bi-Heng Liu, Yun-Feng Huang, Chuan-Feng Li, Guang-Can Guo, Giulio Chiribella
Quantum theory allows information to flow through a single device in a coherent superposition of two opposite directions, resulting into situations where the input-output direction is indefinite. Here we introduce a theoretical method to witness input-output indefiniteness in a single quantum device, and we experimentally demonstrate it by constructing a photonic setup that exhibits input-output indefiniteness with a statistical significance exceeding 69 standard deviations. Our results provide a way to characterize input-output indefiniteness as a resource for quantum information and photonic quantum technologies and enable tabletop simulations of hypothetical scenarios exhibiting quantum indefiniteness in the direction of time...
April 19, 2024: Physical Review Letters
#7
JOURNAL ARTICLE
Gianluca Passarelli, Xhek Turkeshi, Angelo Russomanno, Procolo Lucignano, Marco Schirò, Rosario Fazio
We study the properties of a monitored ensemble of atoms driven by a laser field and in the presence of collective decay. The properties of the quantum trajectories describing the atomic cloud drastically depend on the monitoring protocol and are distinct from those of the average density matrix. By varying the strength of the external drive, a measurement-induced phase transition occurs separating two phases with entanglement entropy scaling subextensively with the system size. Incidentally, the critical point coincides with the superradiance transition of the trajectory-averaged dynamics...
April 19, 2024: Physical Review Letters
#8
JOURNAL ARTICLE
Plasmon-Induced Ultrafast Hot Hole Transfer in Nonstoichiometric Cu x In y S/CdS Heteronanocrystals.
Nitika Kharbanda, Manvi Sachdeva, Nandan Ghorai, Arshdeep Kaur, Vikas Kumar, Hirendra N Ghosh
Plasmonic semiconductors are promising candidates for developing energy conversion devices due to their tunable band gap, cost-effectiveness, and nontoxicity. Such materials exhibit remarkable capabilities for harvesting infrared photons, which constitute half of the solar energy spectrum. Herein, we have synthesized near-infrared (NIR) active Cu x In y S nanocrystals and Cu x In y S/CdS heterostructure nanocrystals (HNCs) to investigate plasmon-induced charge transfer dynamics on an ultrafast time scale. Employing femtosecond transient absorption spectroscopy, we demonstrate that upon exciting the HNCs with sub-band gap NIR photons (λ = 840 nm), the hot holes are generated in the valence band of plasmonic Cu x In y S and transferred to the adjacent semiconductor...
May 3, 2024: Journal of Physical Chemistry Letters
#9
JOURNAL ARTICLE
Yue Zhang, He Lin Zhao, Siyuan Huang, M Abir Hossain, Arend M van der Zande
Two-dimensional electronic materials are a promising candidate for beyond-silicon electronics due to their favorable size scaling of electronic performance. However, a major challenge is the heterogeneous integration of 2D materials with CMOS processes while maintaining their excellent properties. In particular, there is a knowledge gap in how thin film deposition and processes interact with 2D materials to alter their strain and doping, both of which have a drastic impact on device properties. In this study, we demonstrate how to utilize process-induced strain, a common technique extensively applied in the semiconductor industry, to enhance the carrier mobility in 2D material transistors...
May 3, 2024: ACS Nano
#10
JOURNAL ARTICLE
Pengxiang Dong, Chensheng Lin, Ning Ye, Min Luo
Utilizing the manipulation of perovskite dimensions has been proven as an effective approach in regulating perovskite properties. Nevertheless, achieving precise control over the dimensions of perovskites within the same system poses a significant challenge. In this study, we introduce a sophisticated method to attain precise dimensional control in metal-free perovskites (MFPs), specifically through the process of octahedron tailoring by compositional engineering. Accordingly, we successfully instigated a transition from HPIP-NH4 I3 ⋅H2 O (3D), HPIP2 -NH4 I5 (2D) and HPIP3 -NH4 I7 (1D) structures...
May 3, 2024: Angewandte Chemie
#11
JOURNAL ARTICLE
Gaurav Modi, Andrew C Meng, Srinivasan Rajagopalan, Rangarajan Thiruvengadam, Peter K Davies, Eric A Stach, Ritesh Agarwal
Controlled growth of semiconductor nanowires with atomic precision offers the potential to tune the material properties for integration into scalable functional devices. Despite significant progress in understanding the nanowire growth mechanism, definitive control over atomic positions of its constituents, structure, and morphology via self-assembly remains challenging. Here, we demonstrate an exquisite control over synthesis of cation-ordered nanoscale superstructures in Ge-Sb-Te nanowires with the ability to deterministically vary the nanowire growth direction, crystal facets, and periodicity of cation ordering by tuning the relative precursor flux during synthesis...
May 3, 2024: Nano Letters
#12
JOURNAL ARTICLE
Jonghoon Yoo, Soo Yeon Kang, Ik Joon Jo, Taerim Kim, Gun Tak Lee, Jong Eun Park, Se Uk Lee, Sung Yeon Hwang, Won Chul Cha, Tae Gun Shin, Young Soon Cho, Hyewon Jang, Hee Yoon
As point-of-care ultrasound (POCUS) is increasingly being used in clinical settings, ultrasound education is expanding into student curricula. We aimed to determine the status and awareness of POCUS education in Korean medical schools using a nationwide cross-sectional survey. In October 2021, a survey questionnaire consisting of 20 questions was distributed via e-mail to professors in the emergency medicine (EM) departments of Korean medical schools. The questionnaire encompassed 19 multiple-choice questions covering demographics, current education, perceptions, and barriers, and the final question was an open-ended inquiry seeking suggestions for POCUS education...
May 3, 2024: Medicine (Baltimore)
#13
JOURNAL ARTICLE
Jamie Auxillos, Roxane Crouigneau, Yan-Fang Li, Yifan Dai, Arnaud Stigliani, Isabella Tavernaro, Ute Resch-Genger, Albin Sandelin, Rodolphe Marie, Stine F Pedersen
Despite the physiological and pathophysiological significance of microenvironmental gradients, e.g., for diseases such as cancer, tools for generating such gradients and analyzing their impact are lacking. Here, we present an integrated microfluidic-based workflow that mimics extracellular pH gradients characteristic of solid tumors while enabling high-resolution live imaging of, e.g., cell motility and chemotaxis, and preserving the capacity to capture the spatial transcriptome. Our microfluidic device generates a pH gradient that can be rapidly controlled to mimic spatiotemporal microenvironmental changes over cancer cells embedded in a 3D matrix...
May 3, 2024: Science Advances
#14
JOURNAL ARTICLE
Rui Sun, Ziqi Wang, Brian P Bloom, Andrew H Comstock, Cong Yang, Aeron McConnell, Caleb Clever, Mary Molitoris, Daniel Lamont, Zhao-Hua Cheng, Zhe Yuan, Wei Zhang, Axel Hoffmann, Jun Liu, David H Waldeck, Dali Sun
The chiral induced spin selectivity (CISS) effect, in which the structural chirality of a material determines the preference for the transmission of electrons with one spin orientation over that of the other, is emerging as a design principle for creating next-generation spintronic devices. CISS implies that the spin preference of chiral structures persists upon injection of pure spin currents and can act as a spin analyzer without the need for a ferromagnet. Here, we report an anomalous spin current absorption in chiral metal oxides that manifests a colossal anisotropic nonlocal Gilbert damping with a maximum-to-minimum ratio of up to 1000%...
May 3, 2024: Science Advances
#15
JOURNAL ARTICLE
Ji Jiang, Mingming Shi, Zhengchang Xia, Yong Cheng, Zema Chu, Wei Zhang, Jingzhen Li, Zhigang Yin, Jingbi You, Xingwang Zhang
Perovskite light-emitting diodes (PeLEDs) have attracted great attention in recent years; however, the halogen vacancy defects in perovskite notably hamper the development of high-efficiency devices. Previously, large-sized passivation agents have been usually used, while the effect of defect passivation is limited due to the weak bonding or the large space steric hindrance. Here, we predict that the ultrasmall-sized formate (Fa) and acetate (Ac) have more efficient passivation ability because of the stronger binding with the perovskite, as demonstrated by density functional theory calculation...
May 3, 2024: Science Advances
#16
JOURNAL ARTICLE
In-Yong Suh, Zheng-Yang Huo, Jae-Hwan Jung, Donghyeon Kang, Dong-Min Lee, Young-Jun Kim, Bosung Kim, Jinyoung Jeon, Pin Zhao, Jeonghune Shin, SeongMin Kim, Sang-Woo Kim
Airborne pathogens retain prolonged infectious activity once attached to the indoor environment, posing a pervasive threat to public health. Conventional air filters suffer from ineffective inactivation of the physics-separated microorganisms, and the chemical-based antimicrobial materials face challenges of poor stability/efficiency and inefficient viral inactivation. We, therefore, developed a rapid, reliable antimicrobial method against the attached indoor bacteria/viruses using a large-scale tunneling charge-motivated disinfection device fabricated by directly dispersing monolayer graphene on insulators...
May 3, 2024: Science Advances
#17
JOURNAL ARTICLE
David Hong, Ki Hong Choi, Chul-Min Ahn, Cheol Woong Yu, Ik Hyun Park, Woo Jin Jang, Hyun-Joong Kim, Jang-Whan Bae, Sung Uk Kwon, Hyun-Jong Lee, Wang Soo Lee, Jin-Ok Jeong, Sang-Don Park, Taek Kyu Park, Joo Myung Lee, Young Bin Song, Joo-Yong Hahn, Seung-Hyuk Choi, Hyeon-Cheol Gwon, Jeong Hoon Yang
BACKGROUND: Although culprit-only revascularization during the index procedure has been recommended in patients with acute myocardial infarction (AMI) complicated by cardiogenic shock (CS), the reduction of residual ischemia is also emphasized to improve clinical outcomes. However, few data are available about the significance of residual ischemia in patients undergoing mechanical circulatory supports. This study aimed to evaluate the effects of residual ischemia on clinical outcomes in AMI patients undergoing venoarterial-extracorporeal membrane oxygenation (VA-ECMO)...
May 3, 2024: European Heart Journal. Acute Cardiovascular Care
#18
JOURNAL ARTICLE
Sai P K Panguluri, Elsa Jourdain, Papri Chakraborty, Svetlana Klyatskaya, Manfred M Kappes, Aline M Nonat, Loïc J Charbonnière, Mario Ruben
Lanthanide metal clusters excel in combining molecular and material chemistry properties. Here, we report an efficient cooperative sensitization UC phenomenon of a Eu3+ /Yb3+ nonanuclear lanthanide cluster in CD3 OD. The synthesis and characterization of the heteronuclear cluster in the solid state and solution are described together with the UC phenomenon showing Eu3+ luminescence in the visible region upon 980 nm NIR excitation of Yb3+ at concentrations as low as 100 nM. Alongside being the Eu/Yb cluster to display UC (with a quantum yield value of 4...
May 3, 2024: Journal of the American Chemical Society
#19
JOURNAL ARTICLE
Wei Liu, Timothy Chambers, Kimberly A Clevenger, Karin A Pfeiffer, Zachary Rzotkiewicz, Hyunseo Park, Amber L Pearson
Spending time outdoors is associated with increased time spent in physical activity, lower chronic disease risk, and wellbeing. Many studies rely on self-reported measures, which are prone to recall bias. Other methods rely on features and functions only available in some GPS devices. Thus, a reliable and versatile method to objectively quantify time spent outdoors is needed. This study sought to develop a versatile method to classify indoor and outdoor (I/O) GPS data that can be widely applied using most types of GPS and accelerometer devices...
2024: PloS One
#20
JOURNAL ARTICLE
Yuyang Li, Hui Liu, Li Ding, Liqi Li, Lixiang Wang, Deren Yang, Yanjun Fang
Perovskite nanocrystals (PNCs) offer unique advantages in large-area and thick-film deposition for X-ray detection applications due to the decoupling of the crystallization of perovskite from film formation, as well as their low-temperature and scalable deposition methods. However, the partial detachment of long-chain ligands in PNCs during the purification process would lead to the exposure of surface defects, making it challenging to ensure efficient charge carrier extraction and stable X-ray detection. In this study, we propose a beneficial strategy that involves the in situ reparation of these exposed defects with sodium bromide (NaBr) during the purification process to construct CsPbBr3 PNC-organic bulk heterostructure X-ray detectors...
May 3, 2024: ACS Applied Materials & Interfaces
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