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JOURNAL ARTICLE
Carolin Böing, Marta Di Fabrizio, Domenic Burger, John G J M Bol, Evelien Huisman, Annemieke J M Rozemuller, Wilma D J van de Berg, Henning Stahlberg, Amanda J Lewis
Multiple System Atrophy is characterized pathologically by the accumulation of alpha-synuclein (aSyn) into glial cytoplasmic inclusions (GCIs). The mechanism underlying the formation of GCIs is not well understood. In this study, correlative light and electron microscopy was employed to investigate aSyn pathology in the substantia nigra and putamen of post-mortem multiple system atrophy brain donors. Three distinct types of aSyn immuno-positive inclusions were identified in oligodendrocytes, neurons and dark cells presumed to be dark microglia...
May 2, 2024: Brain
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JOURNAL ARTICLE
Evelyn de Andrade Salomão, Valter Aragão do Nascimento, Iandara Schettert Silva, Priscila Aiko Hiane, Maria Ligia Rodrigues Macedo, Karine Freitas Gielow, Rita de Cassia Avellaneda Guimarães, Murillo Augusto Palhares, Danielle Bogo
Given the importance of discovering plant species from the Brazilian Cerrado biome with anticancer potential, this study evaluated the antitumor activity of two extracts of Campomanesi adamantium fruits in in vitro and in vivo models of melanoma lung metastasis. Pulp and peel extracts (DEGPU and DEGPE, respectively) were extracted from fresh fruit using dichloromethane as a solvent. As cytotoxicity parameter, concentration values that inhibited 50% cell growth (GI50 ), total growth inhibition (TGI), and selectivity index (SI) were established...
May 2, 2024: Journal of Medicinal Food
#3
JOURNAL ARTICLE
Hannah Arem, Danielle A Duarte, Benjamin White, Katie Vinson, Pamela Hinds, Nathan Ball, Kyla Dennis, Darcey M McCready, Lauren A Cafferty, Carla J Berg
Purpose: Young adult cancer survivors experience disruptions in various life domains (e.g., relationships, academic/career) during and after treatment. This study examined life disruptions and related supports to update interventions to improve psychological outcomes. Methods: In April-July 2023, young adult survivors ( n = 23) were recruited (via clinics, support groups, nonprofit organizations, etc.) to complete semi-structured interviews assessing cancer's impact across life domains, how they coped with related disruptions, and facilitators to improved psychosocial well-being...
May 2, 2024: Journal of Adolescent and Young Adult Oncology
#4
JOURNAL ARTICLE
Simon J Mills, Hannah Halstead, Joanne Howie, Selena Hutchins, Leah Forte, David Unsworth, Terri Walters, Miranda Jelbart, Beverley Dodd, Maayken van den Berg, Maggie Killington
PURPOSE: Describe clinical practice, inter-disciplinary clinical pathway and core principles of care within a mild traumatic brain injury (mTBI) rehabilitation team. METHODS: An observational study examined inter-disciplinary practice, nested within an observational trial investigating team-based mTBI rehabilitation. Data were collected to describe clinical service over 12 months. Activity data quantified clinical sessions per participant, mode of service delivery and content of sessions using custom-designed codes...
May 2, 2024: Brain Injury
#5
JOURNAL ARTICLE
Jiawang Tian, Gendi Yin, Qian Zhang, Shuqi Zhang, Xiangli Zeng, Yongqi Li
BACKGROUND: Meniere's disease (MD) is characterized by idiopathic endolymphatic hydrops (ELH). Frequent vertigo attacks is the most disabling symptom of MD. OBJECTIVE: This study evaluated the efficacy of triple semicircular canal occlusion combined with endolymphatic sac decompression in the treatment of frequent vertigo in patients with MD. METHODS: Eleven patients with complete medical records were included in this study conducted from May 2021 to April 2022...
2024: Frontiers in Neurology
#6
JOURNAL ARTICLE
Natalie Heydenrych, Tim De Maayer, Mariette Nel, Louise van den Berg
BACKGROUND: Refeeding syndrome (RFS) is a life-threatening, underdiagnosed, and under-researched complication in treating children with severe acute malnutrition (SAM). This study aimed to determine the incidence and onset of RFS and identify biochemical abnormalities, clinical signs, and complications associated with RFS development in children, 0-59 months, treated with SAM in a South African public hospital setting. METHODS: A retrospective cohort study was performed on hospital medical records of children aged 0-59 months, diagnosed with SAM at Rahima Moosa Mother and Child Hospital, Johannesburg, from 1/10/2014 to 31/12/2018...
May 15, 2024: Heliyon
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JOURNAL ARTICLE
Dawn L Denny, Glenda Lindseth, Thomas Petros, Justin A Berg
BACKGROUND: Interdisciplinary undergraduate students are expected to develop statistical competence to interpret research findings as they advance in their healthcare studies and careers. However, students often report anxiety related to learning statistical course content.This descriptive study examined differences in statistical knowledge and self-efficacy scores of undergraduate students enrolled in online competency-based and traditional learning statistics courses.A sample of 20 nursing and interdisciplinary, undergraduate students from a Midwestern University who were enrolled in introductory statistics courses were recruited for this study...
January 2024: Teaching and Learning in Nursing: Official Journal of the National Organization for Assciate Degree Nursing
#8
JOURNAL ARTICLE
Lindsay S Mayberry, Deborah J Wiebe, Makenzie Parks, MaryJane S Campbell, Aislinn B Beam, Cynthia A Berg
BACKGROUND: Among emerging adults with type 1 diabetes (T1D), self-regulation and social regulation skills can help avoid high A1c and diabetes distress. FAMS (Family/friend Activation to Motivate Self-care) is mobile phone-delivered intervention that supports development of these skills and is efficacious among adults with type 2 diabetes. However, the acceptability and feasibility of the FAMS intervention among emerging adults with T1D are unknown. METHODS: Therefore, we adapted FAMS for in a new disease context and developmental stage and then conducted a 3-month mixed-methods pre-post pilot study...
April 30, 2024: Pilot and Feasibility Studies
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JOURNAL ARTICLE
Kristian Tjelle, Håvard Berg Opstad, Stian Solem, Gerd Kvale, Michael G Wheaton, Thröstur Björgvinsson, Bjarne Hansen, Kristen Hagen
BACKGROUND: Exposure and response prevention (ERP) is considered the first-line psychotherapy for obsessive-compulsive disorder (OCD). Substantial research supports the effectiveness of ERP, yet a notable portion of patients do not fully respond while others experience relapse. Understanding poor outcomes such as these necessitates further research. This study investigated the role of patient adherence to ERP tasks in concentrated exposure treatment (cET) in a sample who had previously not responded to treatment or relapsed...
April 30, 2024: BMC Psychiatry
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JOURNAL ARTICLE
Yuichi Katsura, Satoshi Ohga, Kazuhiro Shimo, Takafumi Hattori, Tsukasa Yamada, Takako Matsubara
This prospective cohort study aimed to identify the risk factors for post-stroke complex regional pain syndrome (CRPS) using a decision tree algorithm while comprehensively assessing upper limb and lower limb disuse and physical inactivity. Upper limb disuse (Fugl-Meyer assessment of upper extremity [FMA-UE], Action Research Arm Test, Motor Activity Log), lower limb disuse (Fugl-Meyer Assessment of lower extremity [FMA-LE]), balance performance (Berg balance scale), and physical inactivity time (International Physical Activity Questionnaire-Short Form [IPAQ-SF]) of 195 stroke patients who visited the Kishiwada Rehabilitation Hospital were assessed at admission...
April 30, 2024: Scientific Reports
#11
JOURNAL ARTICLE
C Rotvig, O Ekholm, A V Christensen, S K Berg
OBJECTIVES: This study aimed to estimate the prevalence of children aged 0-19 years who have a parent with a history of heart disease and investigate their sociodemographic characteristics. STUDY DESIGN: A national register-based study. METHODS: From the Danish Fertility Register and the Danish National Patient Register information on children of parents with ischemic heart disease, arrhythmia, heart failure and heart valve disease in the period 1981-2018 were obtained...
April 29, 2024: Public Health
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REVIEW
Winfried Rief, Gordon J G Asmundson, Richard A Bryant, David M Clark, Anke Ehlers, Emily A Holmes, Richard J McNally, Carmem B Neufeld, Sabine Wilhelm, Adam C Jaroszewski, Max Berg, Anke Haberkamp, Stefan G Hofmann
Although psychological treatments are broadly recognized as evidence-based interventions for various mental disorders, challenges remain. For example, a substantial proportion of patients receiving such treatments do not fully recover, and many obstacles hinder the dissemination, implementation, and training of psychological treatments. These problems require those in our field to rethink some of our basic models of mental disorders and their treatments, and question how research and practice in clinical psychology should progress...
March 25, 2024: Clinical Psychology Review
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JOURNAL ARTICLE
Hege Berg Henriksen, Markus Dines Knudsen, Anette Hjartåker, Rune Blomhoff, Monica Hauger Carlsen
BACKGROUND: Valid assessment tools are needed when investigating adherence to national dietary and lifestyle guidelines. OBJECTIVE: The relative validity of the new digital food frequency questionnaire, the DIGIKOST-FFQ, against 7-day weighed food records and activity sensors was investigated. METHODS: In total, 77 participants were included in the validation study and completed the DIGIKOST-FFQ and the weighed food record, and of these, 56 (73%) also used the activity sensors...
April 30, 2024: Journal of Medical Internet Research
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JOURNAL ARTICLE
Wendie A Berg
No abstract text is available yet for this article.
April 30, 2024: JAMA Oncology
#15
JOURNAL ARTICLE
Răzvan Alexandru Radu, Vincent Costalat, Michele Romoli, Basel Musmar, James E Siegler, Sherief Ghozy, Jane Khalife, Hamza Salim, Hamza Shaikh, Nimer Adeeb, Hugo H Cuellar-Saenz, Ajith J Thomas, Ramanathan Kadirvel, Mohamad Abdalkader, Piers Klein, Thanh N Nguyen, Jeremy J Heit, Robert W Regenhardt, Joshua D Bernstock, Aman B Patel, James D Rabinov, Christopher J Stapleton, Nicole M Cancelliere, Thomas R Marotta, Vitor Mendes Pereira, Kareem El Naamani, Abdelaziz Amllay, Stavropoula I Tjoumakaris, Pascal Jabbour, Lukas Meyer, Jens Fiehler, Tobias D Faizy, Helena Guerreiro, Anne Dusart, Flavio Bellante, Géraud Forestier, Aymeric Rouchaud, Charbel Mounayer, Anna Luisa Kühn, Ajit S Puri, Christian Dyzmann, Peter T Kan, Marco Colasurdo, Gaultier Marnat, Jérôme Berge, Xavier Barreau, Igor Sibon, Simona Nedelcu, Nils Henninger, Takahiro Ota, Shogo Dofuku, Leonard L L Yeo, Benjamin Yq Tan, Anil Gopinathan, Juan Carlos Martinez-Gutierrez, Sergio Salazar-Marioni, Sunil Sheth, Leonardo Renieri, Carolina Capirossi, Ashkan Mowla, Lina M Chervak, Achala Vagal, Priyank Khandelwal, Arundhati Biswas, Frédéric Clarençon, Mahmoud Elhorany, Kevin Premat, Iacopo Valente, Alessandro Pedicelli, Andrea M Alexandre, João Pedro Filipe, Ricardo Varela, Miguel Quintero-Consuegra, Nestor R Gonzalez, Markus A Ymd, Jessica Jesser, Charlotte Weyland, Adrien Ter Schiphorst, Vivek Yedavalli, Pablo Harker, Yasmin Aziz, Benjamin Gory, Christian Paul Stracke, Constantin Hecker, Monika Killer-Oberpfalzer, Christoph J Griessenauer, Cheng-Yang Hsieh, David S Liebeskind, Illario Tancredi, Robert Fahed, Boris Lubicz, Muhammed Amir Essibayi, Amanda Baker, David Altschul, Luca Scarcia, Erwah Kalsoum, Adam A Dmytriw, Adrien Guenego
BACKGROUND: Optimal anesthetic strategy for the endovascular treatment of stroke is still under debate. Despite scarce data concerning anesthetic management for medium and distal vessel occlusions (MeVOs) some centers empirically support a general anesthesia (GA) strategy in these patients. METHODS: We conducted an international retrospective study of MeVO cases. A propensity score matching algorithm was used to mitigate potential differences across patients undergoing GA and conscious sedation (CS)...
April 30, 2024: Clinical Neuroradiology
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JOURNAL ARTICLE
Kate Dawes, Grahame Simpson, Lauren Lines, Maayken van den Berg
OBJECTIVE: This scoping review aimed to identify manualised programs and practice suggestions to support children's health literacy, behaviors and emotions after a parental acquired brain injury. METHODS: A systematic search of five scientific databases (PsychINFO, MEDLINE, ProQuest, Scopus, Cochrane) and gray literature occurred. Inclusion criteria included: studies and gray literature published 1989 to 2023, in English, child populations with relationship to parental acquired brain injury, identifying manualised programs or practice suggestions via content analysis approach...
April 30, 2024: Brain Injury
#17
JOURNAL ARTICLE
Wendie A Berg, Jeremy M Berg, Andriy I Bandos, Adrienne Vargo, Denise M Chough, Amy H Lu, Marie A Ganott, Amy E Kelly, Bronwyn E Nair, Jamie Y Hartman, Uzma Waheed, Christiane M Hakim, Kimberly S Harnist, Ruthane F Reginella, Dilip D Shinde, Bea A Carlin, Cathy S Cohen, Luisa P Wallace, Jules H Sumkin, Margarita L Zuley
Background Digital breast tomosynthesis (DBT) is often inadequate for screening women with a personal history of breast cancer (PHBC). The ongoing prospective Tomosynthesis or Contrast-Enhanced Mammography, or TOCEM, trial includes three annual screenings with both DBT and contrast-enhanced mammography (CEM). Purpose To perform interim assessment of cancer yield, stage, and recall rate when CEM is added to DBT in women with PHBC. Materials and Methods From October 2019 to December 2022, two radiologists interpreted both examinations: Observer 1 reviewed DBT first and then CEM, and observer 2 reviewed CEM first and then DBT...
April 2024: Radiology
#18
JOURNAL ARTICLE
Andrew B Berg, Mauro S Ferreira Santos, Anthony Bautista, Maria F Mora, Michael T Pauken, Aaron C Noell
Capillary temperature control during capillary electrophoresis (CE) separations is key for achieving accurate and reproducible results with a broad array of potential methods. However, the difficulty of enabling typical fluid temperature control loops on portable instruments has meant that active capillary temperature control of in situ CE systems has frequently been overlooked. This work describes construction and test of a solid-state device for capillary temperature control that is suitable for inclusion with in situ instruments, including those designed for space missions...
April 30, 2024: Electrophoresis
#19
JOURNAL ARTICLE
Aja Noersgaard Buur Tengstedt, Shenglin Liu, Magnus W Jacobsen, Camilla Gundlund, Peter Rask Møller, Søren Berg, Dorte Bekkevold, Michael M Hansen
Population genomics analysis holds great potential for informing conservation of endangered populations. We focused on a controversial case of European whitefish (Coregonus spp.) populations. The endangered North Sea houting is the only coregonid fish that tolerates oceanic salinities and was previously considered a species (C. oxyrhinchus) distinct from European lake whitefish (C. lavaretus). However, no firm evidence for genetic-based salinity adaptation has been available. Also, studies based on microsatellite and mitogenome data suggested surprisingly recent divergence (c...
April 30, 2024: Molecular Ecology
#20
JOURNAL ARTICLE
Cynthia A Berg, Jessica H Mansfield, Silas B Boggess, Julia V Martin, Benjamin Creer, Torri K Peck, Deborah J Wiebe, Jonathan E Butner, Lindsay S Mayberry
OBJECTIVE: Interventions for emerging adults (EAs) with type 1 diabetes (T1D) focus on goal setting, but little is known about how goal achievement relates to intervention outcomes. We examined how goals change, how goal achievement relates to diabetes outcomes, and identified barriers and facilitators to goal achievement. METHOD: EAs with T1D (N=29, M age=21.6 years, 57% female) were coached monthly to set a behavioral goal across a 3-month feasibility trial. Coaching notes were qualitatively coded regarding type, complexity, and changes in goals...
2024: Front Clin Diabetes Healthc
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