Giorgos Papanastasiou, Guang Yang, Dimitris I Fotiadis, Nikolaos Dikaios, Chengjia Wang, Ahsan Huda, Luba Sobolevsky, Jason Raasch, Elena Perez, Gurinder Sidhu, Donna Palumbo
BACKGROUND: Primary immunodeficiency (PI) is a group of heterogeneous disorders resulting from immune system defects. Over 70% of PI is undiagnosed, leading to increased mortality, co-morbidity and healthcare costs. Among PI disorders, combined immunodeficiencies (CID) are characterized by complex immune defects. Common variable immunodeficiency (CVID) is among the most common types of PI. In light of available treatments, it is critical to identify adult patients at risk for CID and CVID, before the development of serious morbidity and mortality...
December 20, 2023: Commun Med (Lond)