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Alexander P Glaser, Abigail R Smith, Dacey Maglaque, Brian T Helfand, Rowida Mohamed, Hosanna An, Melissa Marquez, Pooja Talaty, Padraig Carolan, Aaron M Geller, Francesca R Farina, Sally E Jensen, James W Griffith
Background Lower urinary tract symptoms (LUTS) due to benign prostatic hyperplasia (BPH) significantly impact quality of life among older men. Despite the prevalent use of the American Urological Association Symptom Index (AUA-SI) for BPH, this measure overlooks key symptoms such as pain and incontinence, underscoring the need for more comprehensive patient-reported outcome (PRO) tools. This study aims to integrate enhanced PROs into routine clinical practice to better capture the spectrum of LUTS, thereby improving clinical outcomes and patient care...
May 6, 2024: Research Square
#2
JOURNAL ARTICLE
Griffith B Perkins, James D Zuiani, P Toby Coates
No abstract text is available yet for this article.
May 14, 2024: Kidney International
#3
JOURNAL ARTICLE
Lucy J Griffiths, James Rafferty, Richard Fry, Helen Daniels, Carol Dezateux, Nicola Firman, Theodora Pouliou, Gareth Stratton, Amy Mizen, Ronan A Lyons, Alan Watkins, Jo Davies, Rowena Bailey
BACKGROUND: Routine monitoring of Body Mass Index (BMI) in general practice, and via national surveillance programmes, is essential for the identification, prevention, and management of unhealthy childhood weight. We examined and compared the presence and representativeness of children and young people's (CYPs) BMI recorded in two routinely collected administrative datasets: general practice electronic health records (GP-BMI) and the Child Measurement Programme for Wales (CMP-BMI), which measures height and weight in 4-5-year-old school children...
2024: PloS One
#4
EDITORIAL
Yì Xiáng J Wáng, Wei Yu, Jason C S Leung, James F Griffith, Ben-Heng Xiao, Daniele Diacinti, Ali Guermazi, Wing P Chan, Glen M Blake
No abstract text is available yet for this article.
May 1, 2024: Quantitative Imaging in Medicine and Surgery
#5
JOURNAL ARTICLE
Griffith B Perkins, Matthew J Tunbridge, Plinio R Hurtado, James Zuiani, Shweta Mhatre, Kwok Ho Yip, Thanh-Thao Adriana Le, Carlo Yuson, Frank Kette, Pravin Hissaria
BACKGROUND: Polyethylene glycol (PEG) is a non-protein polymer that is present in its native (unbound) form as an excipient in a range of products, and is increasingly being utilised clinically in the form of PEGylated liposomal medications and vaccines. PEG is the cause of anaphylaxis in a small percentage of drug reactions, however diagnosis of PEG allergy is complicated by the variable and poor diagnostic performance of current skin testing protocols. OBJECTIVE: We assessed the diagnostic performance of PEGylated lipid medications as an alternative to currently described tests that use medications containing PEG excipients...
May 6, 2024: Journal of Allergy and Clinical Immunology
#6
JOURNAL ARTICLE
Siobhan Sutcliffe, Chloe Falke, Cynthia S Fok, James W Griffith, Bernard L Harlow, Kimberly A Kenton, Cora E Lewis, Lisa Kane Low, Jerry L Lowder, Emily S Lukacz, Alayne D Markland, Gerald McGwin, Melanie R Meister, Elizabeth R Mueller, Diane K Newman, Ratna Pakpahan, Leslie M Rickey, Todd Rockwood, Melissa A Simon, Abigail R Smith, Kyle D Rudser, Ariana L Smith
BACKGROUND: To estimate the prevalence of a wide range of lower urinary tract symptoms (LUTS) in US women, and to explore associations with bother and discussion with healthcare providers, friends, and family. MATERIALS AND METHODS: We analyzed baseline data collected from 5/2022-12/2023 in the RISE FOR HEALTH study-a large, regionally-representative cohort study of adult female community members. LUTS and related bother were measured by the 10-item Symptoms of Lower Urinary Tract Dysfunction Research Network Symptom Index and discussion was assessed by a study-specific item...
May 4, 2024: Journal of Urology
#7
JOURNAL ARTICLE
Daniel G Streicker, Megan E Griffiths, Rustom Antia, Laura Bergner, Peter Bowman, Maria Vitoria Dos Santos de Moraes, Kevin Esvelt, Mike Famulare, Amy Gilbert, Biao He, Michael A Jarvis, David A Kennedy, Jennifer Kuzma, Carolyne Nasimiyu Wanyonyi, Christopher Remien, Tonie Rocke, Kyle Rosenke, Courtney Schreiner, Justin Sheen, David Simons, Ivet A Yordanova, James J Bull, Scott L Nuismer
Intrinsically safe designs and a staged transparent development process will be essential.
April 19, 2024: Science
#8
REVIEW
Yì Xiáng J Wáng, Daniele Diacinti, Maria Pilar Aparisi Gómez, Fernando Ruiz Santiago, Fabio Becce, Alberto Stefano Tagliafico, Mahesh Prakash, Amanda Isaac, Danoob Dalili, James F Griffith, Giuseppe Guglielmi, Alberto Bazzocchi
When a low-energy trauma induces an acute vertebral fracture (VF) with clinical symptoms, a definitive diagnosis of osteoporotic vertebral fracture (OVF) can be made. Beyond that, a "gold" radiographic standard to distinguish osteoporotic from non-osteoporotic VFs does not exist. Fracture-shaped vertebral deformity (FSVD) is defined as a deformity radiographically indistinguishable from vertebral fracture according to the best of the reading radiologist's knowledge. FSVD is not uncommon among young populations with normal bone strength...
April 25, 2024: Skeletal Radiology
#9
JOURNAL ARTICLE
Amy S Paller, Stephanie M Rangel, Sarah L Chamlin, Aleena Hajek, Sheshanna Phan, Marcia Hogeling, Leslie Castelo-Soccio, Irene Lara-Corrales, Lisa Arkin, Leslie P Lawley, Tracy Funk, Fabiana Castro Porto Silva Lopes, Richard J Antaya, Michele L Ramien, Karina L Vivar, Joyce Teng, Carrie C Coughlin, Wingfield Rehmus, Deepti Gupta, Lionel Bercovitch, Sarah L Stein, Christina Boull, Wynnis L Tom, Marilyn G Liang, Raegan Hunt, Minnelly Luu, Kristen E Holland, Jennifer J Schoch, David Cella, Jin-Shei Lai, James W Griffith
IMPORTANCE: Chronic skin disorders in children frequently are visible and can cause stigmatization. However, the extent of stigmatization from chronic skin disease and association with mental health needs further study. OBJECTIVE: To examine the extent of stigma, dependence on disease visibility and severity, and association with mental health and quality of life (QOL) in chronic pediatric skin disease. DESIGN, SETTING, AND PARTICIPANTS: A cross-sectional, single-visit study was conducted at 32 pediatric dermatology centers in the US and Canada from November 14, 2018, to November 17, 2021...
April 24, 2024: JAMA Dermatology
#10
JOURNAL ARTICLE
Sarah Clifford, Cassandra J C Wright, Peter G Miller, Kerri Coomber, Kalinda E Griffiths, James A Smith, Michael Livingston
BACKGROUND: During 2017-18, the Northern Territory (NT) introduced a Banned Drinker Register (BDR) and Minimum Unit Price (MUP) NT-wide; Police Auxiliary Liquor Inspectors (PALIs) in three regional towns; and restrictions on daily purchases/opening hours (DPOH) in one regional town. The BDR is an individual-level alcohol ban; MUP is a pricing policy; and PALIs enforce bans on restricted areas at takeaway outlets. This study examines the impact of these policies on adult domestic and family violence (DFV)...
April 18, 2024: International Journal on Drug Policy
#11
JOURNAL ARTICLE
Ratko Djukanović, Paul Brinkman, Johan Kolmert, Cristina Gomez, James Schofield, Joost Brandsma, Andy Shapanis, Paul J S Skipp, Anthony Postle, Craig Wheelock, Sven-Erik Dahlen, Peter J Sterk, Thomas Brown, David J Jackson, Adel Mansur, Ian Pavord, Mitesh Patel, Christopher Brightling, Salman Siddiqui, Peter Bradding, Ian Sabroe, Dinesh Saralaya, Livingstone Chishimba, Joanna Porter, Douglas Robinson, Stephen Fowler, Peter H Howarth, Louisa Little, Thomas Oliver, Kayleigh Hill, Louise Stanton, Alexander Allen, Deborah Ellis, Gareth Griffiths, Tim Harrison, Ayobami Akenroye, Jessica Lasky-Su, Liam Heaney, Rekha Chaudhuri, Ramesh Kurukulaaratchy
BACKGROUND: The anti-IgE monoclonal, omalizumab, is widely used for severe asthma. This study aimed to identify biomarkers that predict clinical improvement during one year of omalizumab treatment. METHODS: 1-year, open-label, S tudy o f M echanisms of action of O malizumab in S evere A sthma ( SoMOSA ) involving 216 severe (GINA step 4/5) uncontrolled atopic asthmatics (≥2 severe exacerbations in previous year) on high-dose inhaled corticosteroids, long-acting β-agonists, ± mOCS...
April 18, 2024: American Journal of Respiratory and Critical Care Medicine
#12
James Reigle, Oscar Lopez-Nunez, Erik Drysdale, Dua Abuquteish, Xiaoxuan Liu, Juan Putra, Lauren Erdman, Anne M Griffiths, Surya Prasath, Iram Siddiqui, Jasbir Dhaliwal
BACKGROUND: Accurate identification of inflammatory cells from mucosal histopathology images is important in diagnosing ulcerative colitis. The identification of eosinophils in the colonic mucosa has been associated with disease course. Cell counting is not only time-consuming but can also be subjective to human biases. In this study we developed an automatic eosinophilic cell counting tool from mucosal histopathology images, using deep learning. METHOD: Four pediatric IBD pathologists from two North American pediatric hospitals annotated 530 crops from 143 standard-of-care hematoxylin and eosin (H & E) rectal mucosal biopsies...
April 5, 2024: medRxiv
#13
JOURNAL ARTICLE
James F Griffith, Jeremiah C H Lee
BACKGROUND: The developmental size of the cervical spinal canal varies considerably. Neural compression and injury are more likely with a developmentally small spinal canal. This study was designed to develop a population reference range for developmental cervical spinal canal size for the Hong Kong population. METHODS: Prospective study of 522 ambulatory patients (256 males, 266 females, mean age 55±18 years; range, 20-89 years) who underwent computed tomography (CT) neck examinations...
April 3, 2024: Quantitative Imaging in Medicine and Surgery
#14
JOURNAL ARTICLE
Joel S Burma, James K Griffiths, Andrew P Lapointe, Ibukunoluwa K Oni, Ateyeh Soroush, Joseph Carere, Jonathan D Smirl, Jeff F Dunn
Wearable technology and neuroimaging equipment using photoplethysmography (PPG) have become increasingly popularized in recent years. Several investigations deriving pulse rate variability (PRV) from PPG have demonstrated that a slight bias exists compared to concurrent heart rate variability (HRV) estimates. PPG devices commonly sample at ~20-100 Hz, where the minimum sampling frequency to derive valid PRV metrics is unknown. Further, due to different autonomic innervation, it is unknown if PRV metrics are harmonious between the cerebral and peripheral vasculature...
March 23, 2024: Sensors
#15
Benedict D Michael, Cordelia Dunai, Edward J Needham, Kukatharmini Tharmaratnam, Robyn Williams, Yun Huang, Sarah A Boardman, Jordan J Clark, Parul Sharma, Krishanthi Subramaniam, Greta K Wood, Ceryce Collie, Richard Digby, Alexander Ren, Emma Norton, Maya Leibowitz, Soraya Ebrahimi, Andrew Fower, Hannah Fox, Esteban Tato, Mark A Ellul, Geraint Sunderland, Marie Held, Claire Hetherington, Franklyn N Egbe, Alish Palmos, Kathy Stirrups, Alexander Grundmann, Anne-Cecile Chiollaz, Jean-Charles Sanchez, James P Stewart, Michael Griffiths, Tom Solomon, Gerome Breen, Alasdair J Coles, Nathalie Kingston, John R Bradley, Patrick F Chinnery, Jonathan Cavanagh, Sarosh R Irani, Angela Vincent, J Kenneth Baillie, Peter J Openshaw, Malcolm G Semple, Leonie S Taams, David K Menon
No abstract text is available yet for this article.
April 4, 2024: Nature Communications
#16
JOURNAL ARTICLE
Massimiliano di Pietro, Nigel J Trudgill, Melina Vasileiou, Gaius Longcroft-Wheaton, Alexander W Phillips, James Gossage, Philip V Kaye, Kieran G Foley, Tom Crosby, Sophie Nelson, Helen Griffiths, Muksitur Rahman, Gill Ritchie, Amy Crisp, Stephen Deed, John N Primrose
Barrett's oesophagus is the only known precursor to oesophageal adenocarcinoma, a cancer with very poor prognosis. The main risk factors for Barrett's oesophagus are a history of gastro-oesophageal acid reflux symptoms and obesity. Men, smokers and those with a family history are also at increased risk. Progression from Barrett's oesophagus to cancer occurs via an intermediate stage, known as dysplasia. However, dysplasia and early cancer usually develop without any clinical signs, often in individuals whose symptoms are well controlled by acid suppressant medications; therefore, endoscopic surveillance is recommended to allow for early diagnosis and timely clinical intervention...
March 29, 2024: Gut
#17
EDITORIAL
Anna M Myers, Rachael C Barlow, Gabriele Baldini, Anna M Campbell, Franco Carli, Esther J Carr, Tom Collyer, Gerard Danjoux, June F Davis, Linda Denehy, James Durrand, Chelsia Gillis, Diana M Greenfield, Stuart P Griffiths, Mike Grocott, Liam Humphreys, Sandy Jack, Carol Keen, Denny Z H Levett, Zoe Merchant, John Moore, Susan Moug, William Ricketts, Daniel Santa Mina, John M Saxton, Clare E Shaw, Garry A Tew, Michael Thelwell, Malcolm A West, Robert J Copeland
Prehabilitation aims to optimise patients' physical and psychological status before treatment. The types of outcomes measured to assess the impact of prehabilitation interventions vary across clinical research and service evaluation, limiting the ability to compare between studies and services and to pool data. An international workshop involving academic and clinical experts in cancer prehabilitation was convened in May 2022 at Sheffield Hallam University's Advanced Wellbeing Research Centre, England. The workshop substantiated calls for a core outcome set to advance knowledge and understanding of best practice in cancer prehabilitation and to develop national and international databases to assess outcomes at a population level...
March 23, 2024: British Journal of Anaesthesia
#18
JOURNAL ARTICLE
Siân Lowri Griffiths, Graham K Murray, Yanakan Logeswaran, John Ainsworth, Sophie M Allan, Niyah Campbell, Richard J Drake, Mohammad Zia Ul Haq Katshu, Matthew Machin, Megan A Pope, Sarah A Sullivan, Justin Waring, Tumelo Bogatsu, Julie Kane, Tyler Weetman, Sonia Johnson, James B Kirkbride, Rachel Upthegrove
BACKGROUND: Early intervention in psychosis (EIP) services are nationally mandated in England to provide multidisciplinary care to people experiencing first-episode psychosis, which disproportionately affects deprived and ethnic minority youth. Quality of service provision varies by region, and people from historically underserved populations have unequal access. In other disease areas, including stroke and dementia, national digital registries coupled with clinical decision support systems (CDSSs) have revolutionized the delivery of equitable, evidence-based interventions to transform patient outcomes and reduce population-level disparities in care...
March 19, 2024: JMIR Research Protocols
#19
JOURNAL ARTICLE
Caleb A LaVigne, Timothy B Griffith, Zachary C Hanson, Donald D Davis, James S Kercher, Xavier A Duralde
BACKGROUND: Accurate measurement of glenoid bone loss (GBL) is critical to preoperative planning in cases of recurrent shoulder instability. The concept of critical bone loss has been established with a value of GBL >13.5% being associated with higher failure rate following arthroscopic Bankart Repair. Advanced imaging, such as magnetic resonance imaging (MRI) scans, can be used to quantify GBL prior to surgery using the best-fit circle technique. Surgeons have traditionally relied on visual inspection of the MRI scan preoperatively or on visual inspection of the glenoid at the time of arthroscopy to determine whether GBL is present...
March 2024: JSES international
#20
JOURNAL ARTICLE
Malek Smadi, Eunseo Lee, James Phelan, Aiming Wang, Guillaume J Bilodeau, Stephen F Pernal, M Marta Guarna, Mike Rott, Jonathan S Griffiths
INTRODUCTION: Honey bee ( Apis mellifera ) pollination is widely used in tree fruit production systems to improve fruit set and yield. Many plant viruses can be associated with pollen or transmitted through pollination, and can be detected through bee pollination activities. Honey bees visit multiple plants and flowers in one foraging trip, essentially sampling small amounts of pollen from a wide area. Here we report metagenomics-based area-wide monitoring of plant viruses in cherry ( Prunus avium ) and apple ( Malus domestica ) orchards in Creston Valley, British Columbia, Canada, through bee-mediated pollen sampling...
2024: Frontiers in Plant Science
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