Jessica Proctor, Maria Stadler, Lizette M Cortes, David Brodsky, Lydia Poisson, Volker Gerdts, Alex I Smirnov, Tatyana I Smirnova, Subarna Barua, Darren Leahy, Kenneth W Beagley, Jonathan M Harris, Toni Darville, Tobias Käser
Chlamydia trachomatis ( Ct ) infections are the most common sexually transmitted infection (STI). Despite effective antibiotics for Ct , undetected infections or delayed treatment can lead to infertility, ectopic pregnancies, and chronic pelvic pain. Besides humans, chlamydia poses similar health challenges in animals such as C. suis ( Cs ) in pigs. Based on the similarities between humans and pigs, as well as their chlamydia species, we use pigs as a large biomedical animal model for chlamydia research. In this study, we used the pig model to develop a vaccine candidate against Ct ...
April 16, 2024: Vaccines