keyword
https://read.qxmd.com/read/38687004/de-novo-metastatic-prostate-cancer-presenting-with-atypical-lower-limb-skeletal-metastases-detected-on-68ga-psma-pet-ct
#21
JOURNAL ARTICLE
Alexander Yip, June Yap
Metastatic prostate cancer to the appendicular skeleton is rare. We present an 86-year-old man with undiagnosed prostate cancer presenting with unilateral foot pain. CT and MRI demonstrated a sclerotic midfoot suggestive of an infiltrative process. In view of an elevated PSA, metastatic disease was suspected, and bone scan confirmed osteoblastically active pelvic and lower-limb skeletal lesions. Subsequent prostate biopsy confirmed prostate adenocarcinoma. Staging 68Ga-PSMA PET/CT demonstrated PSMA-avid intraprostatic malignancy with pelvic and right lower-limb skeletal metastases...
April 30, 2024: Clinical Nuclear Medicine
https://read.qxmd.com/read/38686828/assessing-the-utility-of-artificial-intelligence-in-endometriosis-promises-and-pitfalls
#22
REVIEW
Brie Dungate, Dwayne R Tucker, Emma Goodwin, Paul J Yong
Endometriosis, a chronic condition characterized by the growth of endometrial-like tissue outside of the uterus, poses substantial challenges in terms of diagnosis and treatment. Artificial intelligence (AI) has emerged as a promising tool in the field of medicine, offering opportunities to address the complexities of endometriosis. This review explores the current landscape of endometriosis diagnosis and treatment, highlighting the potential of AI to alleviate some of the associated burdens and underscoring common pitfalls and challenges when employing AI algorithms in this context...
2024: Women's Health
https://read.qxmd.com/read/38684268/functional-outcomes-of-bowel-resection-versus-shaving-or-disc-excision-of-colorectal-endometriosis-a-systematic-review-protocol
#23
JOURNAL ARTICLE
William Qian, Chahaya Gauci, Kanika Chaudhri, Thomas Lung, Ali Mohtashami
INTRODUCTION: Endometriosis is a prevalent gynaecological condition for women of reproductive age worldwide. While endometriosis primarily involves the reproductive system, it can also infiltrate additional viscera such as the gastrointestinal tract. Patients with colorectal endometriosis can have severe symptoms that require surgical intervention. There are limited data available to guide the choice of resection technique based on the functional outcomes of bowel resection versus shaving or disc excision in treating colorectal endometriosis...
April 28, 2024: BMJ Open
https://read.qxmd.com/read/38682290/presence-of-endometriosis-and-chronic-overlapping-pain-conditions-negatively-impacts-the-pain-experience-in-women-with-chronic-pelvic-abdominal-pain-a-cross-sectional-survey
#24
JOURNAL ARTICLE
Emily J Bartley, Meryl J Alappattu, Kelsey Manko, Hannah Lewis, Terrie Vasilopoulos, Georgine Lamvu
BACKGROUND: Evidence of overlap between endometriosis and chronic pain conditions is emerging; however, little is known about how the pain experience differs based on the presence or absence of endometriosis. OBJECTIVES: In a sample of women reporting chronic pelvic-abdominal pain (CPP), the aim of this study was to characterize differences in pain symptomatology between women with and without endometriosis and to examine the influence of chronic overlapping pain conditions (COPCs) on pain among these two groups...
2024: Women's Health
https://read.qxmd.com/read/38681322/recurrent-ureterosciatic-herniation-causing-right-obstructive-uropathy
#25
Eduardo García-Rico, Luis Enrique Ortega-Polledo, Diego M Carrion, Ana Quiroga-Valcarcel, Laura Fernández Hernández
Sciatic hernias are unusual, challenging to diagnose, and can present some treatment dilemmas. Sciatic hernias containing the ureter are even less common. Symptoms are variable from renal fossa pain, mild or severe pelvic pain, neuropathic pain, or dysesthesias. Although stenting alone can be a treatment option for this condition, in cases where symptoms or ureteral obstruction relapse after initial treatment, sciatic hernioplasty must be considered as the definitive treatment. This article presents the case of a female patient who presented with a history of nonspecific abdominal pain and was diagnosed with a right-sided ureterosciatic hernia...
March 2024: Curēus
https://read.qxmd.com/read/38681163/hematometra-a-rare-case-of-pelvic-pain-in-females-identified-with-point-of-care-ultrasound
#26
Andrew R Helber, Margaret Provencher, Christy Moore, Nova Panebianco
The differential diagnosis for abdominal or pelvic pain in women of child-bearing age that present to the emergency department is broad. A rare cause of abdominal and pelvic pain is hematometra, or a collection of blood products within the uterus. While blood is normally expelled through menses, this process is disrupted in some patients due to congenital or acquired abnormalities. This can lead to progressive uterine distension and pain, which may ultimately require medical or surgical intervention. Hematometra is rare, but is a serious condition that can be diagnosed easily at bedside using point of care ultrasound...
2024: POCUS J
https://read.qxmd.com/read/38681049/case-report-ureteric-bud-intestinal-type-adenocarcinoma-involving-the-cervix-was-misdiagnosed-as-a-large-cervical-fibroid
#27
Li-Li Zhang, Li Wang, Dan-Ni Zhang, Jun-Tong Wu, Yuan Liu, Yan-Ping Wang
BACKGROUND: Malignant tumors of the ureteric bud are not common, and cervical involvement is even rarer. So far, there have been no such cases in the literature. CASE SUMMARY: A 50-year-old woman developed intermittent light bleeding in the past 7 months and lower abdominal pain in the past 2 months. The human papillomavirus 16 (HPV) DNA, P16 chemical staining, thinPrep cytology test (TCT), and cervical and cervical canal tissue biopsy were all negative...
2024: Frontiers in Medicine
https://read.qxmd.com/read/38680596/a-unique-presentation-of-the-rare-nora-s-lesion-symptomatic-bizarre-parosteal-osteochondromatous-proliferation-a-case-report
#28
Alan Katz, Joshua Cohen, Tanya Lishchynovska, Joseph Alberton, Amos Peyser
Bizarre parosteal osteochondromatous proliferations, also known as Nora's lesions, are rare benign tumors with a high recurrence rate. They are often difficult to identify because of their similar appearance to other tumors. We describe a 25-year-old healthy female patient with bizarre parosteal osteochondromatous proliferations in an uncommon location on the pelvic ilium, presenting with unique clinical findings of abdominal pain and femoral paresthesia and showing atypical radiographic findings. To the best of our knowledge, this is one of the very few cases ever reported in the literature of Nora's lesion in this particular location and possibly the first case ever with this specific presentation...
2024: SAGE Open Medical Case Reports
https://read.qxmd.com/read/38680134/late-surgical-correction-after-complex-unstable-pelvic-fracture-61-c3-ota-ao-of-an-18-year-old-woman
#29
Oleksandr Rikhter
Surgical fixation of pelvic fractures is often necessary to restore fracture stability and improve patient outcomes. However, early operative management of pelvis fractures is not widely available in many health systems, resulting in conservative treatment approaches. Conservative approaches can lead to uncorrected pelvic deformities, which are challenging to treat and increase the risk of serious complications such as malunion. Treatment of pelvic malunion requires specialized care, access to necessary equipment, and a clearly defined treatment protocol...
June 2024: OTA international: the open access journal of orthopaedic trauma
https://read.qxmd.com/read/38679887/clinical-and-radiological-predictors-of-slower-and-non-improvement-following-surgical-treatment-of-l4-5-degenerative-spondylolisthesis-preliminary-results
#30
JOURNAL ARTICLE
Sumedha Singh, Pratyush Shahi, Junho Song, Tejas Subramanian, Kyle Morse, Omri Maayan, Kasra Araghi, Nishtha Singh, Olivia Tuma, Tomoyuki Asada, Maximilian Korsun, Eric Mai, James Dowdell, Evan Sheha, Harvinder Sandhu, Todd Albert, Sheeraz Qureshi, Sravisht Iyer
STUDY DESIGN: Retrospective cohort. OBJECTIVE: To identify the predictors of slower and non-improvement following surgical treatment of L4-5 degenerative lumbar spondylolisthesis (DLS). SUMMARY OF BACKGROUND DATA: There is limited evidence regarding clinical and radiological predictors of slower and non-improvement following surgery for L4-5 DLS. METHODS: Patients who underwent minimally invasive decompression or fusion for L4-5 DLS and had a minimum of 1-year follow-up were included...
April 29, 2024: Spine
https://read.qxmd.com/read/38679794/precise-capture-of-circulating-endometrial-cells-in-endometriosis
#31
JOURNAL ARTICLE
Shang Wang, Hongyan Cheng, Honglan Zhu, Xiaoming Yu, Xue Ye, Xiaohong Chang
BACKGROUND: Endometriosis (EM) is a complex benign gynecological disease, but it has malignant biological behavior and can invade any part of the body. Clinical manifestations include pelvic pain, dysmenorrhea, infertility, pelvic nodules, and masses. Our previous study successfully detected circulating endometrial cells (CECs) in the peripheral blood of patients with EM. The purpose of this study is to overcome the limitation of cell size in the previous microfluidic chip method, to further accurately capture CECs, understand the characteristics of these cells, and explore the relationship between CECs and the clinical course characteristics of patients with EM...
April 29, 2024: Chinese Medical Journal
https://read.qxmd.com/read/38678989/extraction-of-a-giant-bladder-stone-560%C3%A2-g-in-a-young-female-a-case-report
#32
Moutasem Mansor Mosa, Zein A Alsayed-Ahmad, Qusai Razzouk, Osama Alhmaidy, Hani Ismaeel, Yamen Al Ahmad
INTRODUCTION AND IMPORTANCE: Giant bladder stones, exceeding 100 g, are rare and typically affect males. This report describes an atypical case of a 35-year-old female with a 560-g bladder stone causing acute kidney injury without evidence of upper urinary tract stones. CASE PRESENTATION: A 35-year-old female presented with pelvic pain and urinary retention. Comprehensive imaging, including a KUB x-ray and subsequent ultrasound, revealed a giant bladder stone obstructing the ureters and causing bilateral hydronephrosis...
April 20, 2024: International Journal of Surgery Case Reports
https://read.qxmd.com/read/38678773/vestibulodynia-clinical-characteristics-first-line-treatments-and-factors-associated-with-escalation-of-treatment-with-emg-guided-injections-of-botulinum-toxin-in-a-retrospective-french-cohort-study
#33
JOURNAL ARTICLE
C Neuville, B Parratte, S Lombion, F Aubin, I Gallais Sérézal, F Pelletier
BACKGROUND: Vestibulodynia is a highly prevalent chronic pain disorder affecting the vulva having a major impact on women's physical, psychological, and sexual well-being. It remains an underrecognized disease that responds insufficiently to therapies such as physiotherapy and medication. AIM: To assess the global efficacy of first-line therapies and factors associated with treatment escalation in women with vestibulodynia. PATIENTS AND METHODS: This retrospective cohort study was conducted at the dermatology outpatient clinic of the University Hospital in Besancon (France) between 2013 and 2017 and follow-up until 2021...
April 27, 2024: Annales de Dermatologie et de Vénéréologie
https://read.qxmd.com/read/38677550/a-scoping-review-of-scores-or-grading-systems-for-pelvic-venous-disorders-pevd
#34
REVIEW
Konstantinos Kavallieros, Tasneem Pope, Konstantinos Mantonanakis, Matthew Tan, Sergio Gianesini, Zaza Lazarashvili, Aleksandra Jaworucka-Kaczorowska, Sriram Narayanan, Adam M Gwozdz, Alun H Davies
BACKGROUND: Pelvic Venous Disorders (PeVD) encompass many conditions linked to chronic pelvic pain (CPP) in women. However, PeVD remain underdiagnosed due to the absence of universally accepted diagnostic criteria. The complexity of PeVD classification across specialties leads to delays in treatment. This scoping review aims to fill a gap in PeVD diagnosis and management by identifying all existing scoring or grading systems, to lay the foundation for standardised clinical scoring tools for PeVD...
April 25, 2024: Journal of Vascular Surgery. Venous and Lymphatic Disorders
https://read.qxmd.com/read/38677096/saliva-based-microrna-diagnostic-signature-for-the-superficial-peritoneal-endometriosis-phenotype
#35
JOURNAL ARTICLE
Sofiane Bendifallah, Yohann Dabi, Stéphane Suisse, Johanna Ilic, Léa Delbos, Mathieu Poilblanc, Philippe Descamps, Francois Golfier, Ludmila Jornea, Delphine Bouteiller, Cyril Touboul, Anne Puchar, Emile Daraï
OBJECTIVE: Patients with superficial peritoneal endometriosis (SPE) present with symptoms suggestive of endometriosis but clinical and imaging exams are inconclusive. Consequently, laparoscopy is usually necessary to confirm diagnosis. The present study aimed to evaluate the accuracy of microRNAs (miRNAs) to diagnose patients with SPE from the ENDOmiARN cohort STUDY DESIGN: This prospective study (NCT04728152) included 200 saliva samples obtained between January and June 2021 from women with pelvic pain suggestive of endometriosis...
April 17, 2024: European Journal of Obstetrics, Gynecology, and Reproductive Biology
https://read.qxmd.com/read/38676541/association-between-non-penetrative-sexual-activities-and-depression-in-women-with-vaginismus-a-cross-sectional-study
#36
JOURNAL ARTICLE
Şeyda Yavuzkir, Melike Aslan, Nurdan Yurt, Sema Baykara
OBJECTIVE: This cross-sectional study aimed to explore the association between non-penetrative sexual activities (NPSA) and depression levels in women diagnosed with vaginismus. METHODS: A cross-sectional retrospective study was conducted between March 2016 and June 2019, after approval by the Fırat University Faculty of Medicine ethics committee. Participants comprised married women referred to our female sexual dysfunction outpatient clinic with vaginismus...
April 2024: Journal of International Medical Research
https://read.qxmd.com/read/38675805/a-triadj-adjuvanted-chlamydia-trachomatis-cpaf-protein-vaccine-is-highly-immunogenic-in-pigs
#37
JOURNAL ARTICLE
Jessica Proctor, Maria Stadler, Lizette M Cortes, David Brodsky, Lydia Poisson, Volker Gerdts, Alex I Smirnov, Tatyana I Smirnova, Subarna Barua, Darren Leahy, Kenneth W Beagley, Jonathan M Harris, Toni Darville, Tobias Käser
Chlamydia trachomatis ( Ct ) infections are the most common sexually transmitted infection (STI). Despite effective antibiotics for Ct , undetected infections or delayed treatment can lead to infertility, ectopic pregnancies, and chronic pelvic pain. Besides humans, chlamydia poses similar health challenges in animals such as C. suis ( Cs ) in pigs. Based on the similarities between humans and pigs, as well as their chlamydia species, we use pigs as a large biomedical animal model for chlamydia research. In this study, we used the pig model to develop a vaccine candidate against Ct ...
April 16, 2024: Vaccines
https://read.qxmd.com/read/38673609/sonography-as-a-diagnostic-tool-in-midurethral-sling-complications-a-narrative-review
#38
REVIEW
Aneta Zwierzchowska, Paweł Tomasik, Edyta Horosz, Ewa Barcz
Despite the established safety and efficacy of midurethral slings (MUS), which are the current gold standard treatment for stress urinary incontinence (SUI), the potential for postoperative complications remains a significant concern for both healthcare professionals and patients. Meanwhile, sonography has emerged as a significant diagnostic tool in urogynecology, and one of the applications of this imaging modality may be the evaluation of complications arising from MUS procedures. This review, based on a comprehensive literature search, focuses on the use of pelvic floor ultrasound (US) in the context of MUS complications...
April 18, 2024: Journal of Clinical Medicine
https://read.qxmd.com/read/38673556/malignancy-in-abdominal-wall-endometriosis-is-there-a-way-to-avoid-it-a-systematic-review
#39
REVIEW
Julie Alaert, Mathilde Lancelle, Marie Timmermans, Panayiotis Tanos, Michelle Nisolle, Stavros Karampelas
Background: Malignant-associated abdominal wall endometriosis (AWE) is a rare pathology, likely to occur in 1% of scar endometriosis. The objectives of this study were to update the evidence on tumor degeneration arising from AWE to notify about the clinical characteristics, the different treatments offered to patients and their outcomes. Methods: A comprehensive systematic review of the literature was conducted. PubMed, Embase and Cochrane Library databases were used. Prospero (ID number: CRD42024505274). Results: Out of the 152 studies identified, 63 were included, which involved 73 patients...
April 15, 2024: Journal of Clinical Medicine
https://read.qxmd.com/read/38673450/can-the-mismatch-of-measured-pelvic-morphology-vs-lumbar-lordosis-predict-chronic-low-back-pain-patients
#40
JOURNAL ARTICLE
Deed E Harrison, Jason W Haas, Ibrahim M Moustafa, Joseph W Betz, Paul A Oakley
Background : Measures of lumbar lordosis (LL) and elliptical modeling variables have been shown to discriminate between normal and chronic low back pain (CLBP) patients. Pelvic morphology influences an individual's sagittal lumbar alignment. Our purpose is to investigate the sensitivity and specificity of lumbar sagittal radiographic alignment and modeling variables to identify if these can discriminate between normal controls and CLBP patients. Methods : We conducted a computer analysis of digitized vertebral body corners on lateral lumbar radiographs of normal controls and CLBP patients...
April 10, 2024: Journal of Clinical Medicine
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