Jamshid Maddahi, Denis Agostini, Timothy M Bateman, Jeroen J Bax, Rob S B Beanlands, Daniel S Berman, Sharmila Dorbala, Ernest V Garcia, James Feldman, Gary V Heller, Juhani M Knuuti, Pedro Martinez-Clark, Matthieu Pelletier-Galarneau, Benjamin Shepple, Nagara Tamaki, Francois Tranquart, James E Udelson
BACKGROUND: Flurpiridaz F-18 (flurpiridaz) is a novel positron emission tomography (PET) myocardial perfusion imaging tracer. OBJECTIVES: The purpose of this study was to further assess the diagnostic efficacy and safety of flurpiridaz for the detection and evaluation of coronary artery disease (CAD) defined as ≥50% stenosis by quantitative invasive coronary angiography (ICA). METHODS: In this second phase 3 prospective multicenter clinical study, 730 patients with suspected CAD from 48 clinical sites in the United States, Canada, and Europe were enrolled...
October 17, 2023: Journal of the American College of Cardiology