keyword
https://read.qxmd.com/read/38696773/efficacy-of-the-flo-app-in-improving-health-literacy-menstrual-and-general-health-and-well-being-in-women-pilot-randomized-controlled-trial
#1
RANDOMIZED CONTROLLED TRIAL
Adam C Cunningham, Carley Prentice, Kimberly Peven, Aidan Wickham, Ryan Bamford, Tara Radovic, Anna Klepchukova, Maria Fomina, Katja Cunningham, Sarah Hill, Liisa Hantsoo, Jennifer Payne, Liudmila Zhaunova, Sonia Ponzo
BACKGROUND: Reproductive health literacy and menstrual health awareness play a crucial role in ensuring the health and well-being of women and people who menstruate. Further, awareness of one's own menstrual cycle patterns and associated symptoms can help individuals identify and manage conditions of the menstrual cycle such as premenstrual syndrome (PMS) and premenstrual dysphoric disorder (PMDD). Digital health products, and specifically menstrual health apps, have the potential to effect positive change due to their scalability and ease of access...
May 2, 2024: JMIR MHealth and UHealth
https://read.qxmd.com/read/38696746/health-care-seeking-behaviour-in-patients-with-hypertension-experience-from-a-dedicated-hypertension-centre-in-bangladesh
#2
JOURNAL ARTICLE
Mohammad Jahid Hasan, Md Zakir Hossain, Md Anwar Hossain, Koustuv Dalal, Md Abdul Baset, Probal Sutradhar, Mahabubul Alam, Tamanna Tabassum, Jannatul Fardous, Paramita Zaman, Md Abdur Rafi, Md Abdullah Saeed Khan, Mohammad Delwer Hossain Hawlader
Objective: The study aimed to assess health-seeking behaviour (HSB) and associated factors among hypertensive patients in Bangladesh. Methods: This cross-sectional study was conducted in the Hypertension & Research Centre, Rangpur, Bangladesh, between January 2022 and June 2022. A total of 497 hypertensive adults were recruited consecutively. A pre-tested structured questionnaire was deployed by the research team for data collection. Multivariable logistic regression analysis was used to explore the predictors of HSB...
December 2024: Blood Pressure
https://read.qxmd.com/read/38696726/congenital-myasthenic-syndromes-in-adults-clinical-features-diagnosis-and-long-term-prognosis
#3
JOURNAL ARTICLE
Julian Theuriet, Marion Masingue, Anthony Behin, Ana Ferreiro, Guillaume Bassez, Pauline Jaubert, Oriana Tarabay, Frédéric Fer, Antoine Pegat, Françoise Bouhour, Juliette Svahn, Philippe Petiot, Laurentiu Jomir, Guy Chauplannaz, Catherine Cornut-Chauvinc, Véronique Manel, Emmanuelle Salort-Campana, Shahram Attarian, Etienne Fortanier, Annie Verschueren, Ludivine Kouton, Jean-Philippe Camdessanché, Céline Tard, Armelle Magot, Yann Péréon, Jean-Baptiste Noury, Marie-Christine Minot-Myhie, Maud Perie, Frederic Taithe, Yacine Farhat, Anne-Laure Millet, Pascal Cintas, Guilhem Solé, Marco Spinazzi, Florence Esselin, Dimitri Renard, Sabrina Sacconi, Andra Ezaru, Edoardo Malfatti, Martial Mallaret, Laurent Magy, Eva Diab, Philippe Merle, Maud Michaud, Maxime Fournier, Aleksandra Nadaj Pakleza, Jean-Baptiste Chanson, Claire Lefeuvre, Pascal Laforet, Pascale Richard, Damien Sternberg, Rocio-Nur Villar-Quiles, Tanya Stojkovic, Bruno Eymard
Congenital myasthenic syndromes (CMS) are clinically and genetically heterogeneous diseases caused by mutations affecting neuromuscular transmission. Even if the first symptoms mainly occur during childhood, adult neurologists must confront this challenging diagnosis and manage these patients throughout their adulthood. However, long-term follow-up data from large cohorts of CMS patients are lacking and the long-term prognosis of these patients is largely unknown. We report the clinical features, diagnostic difficulties, and long-term prognosis of a French nationwide cohort of 235 adult patients with genetically confirmed CMS followed in 23 specialized neuromuscular centres...
May 2, 2024: Brain
https://read.qxmd.com/read/38696673/how-do-attitudes-of-adult-children-toward-long-term-care-change-with-education-international-evidence
#4
JOURNAL ARTICLE
Fatih Cemil Ozbugday, Abdullah Tirgil, Pablo Villalobos Dintrans
Global demographic trends indicate that the world population is aging and education acquisition is increasing. For the first time in history, people are expected to spend more years as adults with living parents than as a parent of teenage children, and the average years of schooling have increased dramatically over the past several decades for many countries. Additionally, family-provided care is still the most important form of care to meet care demands worldwide. As strong filial norms could affect older adults' long-term care decision-making, understanding the link between filial obligations and education is critical under these trends...
May 2, 2024: Journal of Aging & Social Policy
https://read.qxmd.com/read/38696615/precision-in-prevention-tailoring-single-use-negative-pressure-wound-therapy-utilization-through-artificial-intelligence-based-surgical-site-complications-risk-and-cost-modeling
#5
JOURNAL ARTICLE
Barrett J Larson, Ashley Roakes, Steve Yurick, Nathan A Netravali
Background: Surgical site complications (SSCs) are common, yet preventable hospital-acquired conditions. Single-use negative pressure wound therapy (sNPWT) has been shown to be effective in reducing rates of these complications. In the era of value-based care, strategic allocation of sNPWT is needed to optimize both clinical and financial outcomes. Materials and Methods: We conducted a retrospective analysis using data from the Premier Healthcare Database (2017-2021) for 10 representative open procedures in orthopedic, abdominal, cardiovascular, cesarean delivery, and breast surgery...
May 2, 2024: Surgical Infections
https://read.qxmd.com/read/38696541/a-protocol-of-a-pilot-randomised-trial-action-respond-to-support-rural-and-regional-communities-with-implementing-community-based-systems-thinking-obesity-prevention-initiatives
#6
RANDOMIZED CONTROLLED TRIAL
Sze Lin Yoong, Andrew D Brown, Gloria K W Leung, Monique Hillenaar, Jennifer L David, Josh Hayward, Claudia Strugnell, Colin Bell, Vicki Brown, Michelle Jackson, Steven Allender
BACKGROUND: Over a quarter of children aged 2-17 years living in Australia are overweight or obese, with a higher prevalence reported in regional and remote communities. Systems thinking approaches that seek to support communities to generate and implement locally appropriate solutions targeting intertwined environmental, political, sociocultural, and individual determinants of obesity have the potential to ameliorate this. There have however been reported challenges with implementation of such initiatives, which may be strengthened by incorporating implementation science methods...
2024: PloS One
https://read.qxmd.com/read/38696538/clinical-management-and-outcome-of-head-and-neck-paragangliomas-hnpgls-a-single-centre-retrospective-study
#7
JOURNAL ARTICLE
Milad Darrat, Louis Lau, Colin Leonard, Stephen Cooke, Muhammad A Shahzad, Claire McHenry, David R McCance, Steven J Hunter, Karen Mullan, John R Lindsay, Una Graham, Neil Bailie, Susie Hampton, Simon Rajendran, Fionnuala Houghton, David Conkey, Patrick J Morrison, Philip C Johnston
CONTEXT: Head and neck paragangliomas (HNPGLs) are rare, usually benign, slow-growing tumours arising from neural crest-derived tissue. Definitive management pathways for HNPGLs have yet to be clearly defined. OBJECTIVE: To review our experience of the clinical features and management of these tumours and to analyse outcomes of different treatment modalities. METHODS: Demographic and clinical data were obtained from The Northern Ireland Electronic Care Record (NIECR) as well from a prospectively maintained HNPGL database between January 2011 through December 2023...
May 2, 2024: Clinical Endocrinology
https://read.qxmd.com/read/38696519/current-utility-of-first-line-ft4-and-tsh-in-screening-for-central-hypothyroidism
#8
JOURNAL ARTICLE
Carol Evans, Jiya Jacob, Annabel Rodham, Manjot Gill, Laura Parry, Alan Dodd, Nadia El-Farhan, Angharad Shore, Andrew Lansdown, Aled Rees, Onyebuchi E Okosieme
BACKGROUND: Thyroid testing strategies vary across laboratories. First-line combined thyroid stimulating hormone (TSH) and freeT4 (FT4) have historically been preferred by many laboratories as this detects individuals with undiagnosed central hypothyroidism who can be missed with a first-line TSH-only strategy. However, an up-to-date evaluation of the utility of this approach is lacking. OBJECTIVES: We investigated the clinical utility of first-line TSH and FT4 in the detection of central hypothyroidism in current day practice...
May 2, 2024: Clinical Endocrinology
https://read.qxmd.com/read/38696497/the-economic-burden-of-multimorbidity-protocol-for-a-systematic-review
#9
JOURNAL ARTICLE
Amrit Banstola, Nana Anokye, Subhash Pokhrel
Multimorbidity, also known as multiple long-term conditions, leads to higher healthcare utilisation, including hospitalisation, readmission, and polypharmacy, as well as a financial burden to families, society, and nations. Despite some progress, the economic burden of multimorbidity remains poorly understood. This paper outlines a protocol for a systematic review that aims to identify and synthesise comprehensive evidence on the economic burden of multimorbidity, considering various definitions and measurements of multimorbidity, including their implications for future cost-of-illness analyses...
2024: PloS One
https://read.qxmd.com/read/38696495/the-chiropractors-dilemma-in-caring-for-older-patients-with-musculoskeletal-complaints-collaborate-integrate-coexist-or-separate
#10
JOURNAL ARTICLE
Cecilia Bergström, Iben Axén, Jonathan Field, Jan Hartvigsen, Monique van der Marck, Dave Newell, Sidney Rubinstein, Annemarie de Zoete, Margareta Persson
The world's elderly population is growing at a rapid pace. This has led to an increase in demand on the health and welfare systems due to age-related disorders, with musculoskeletal complaints driving the need for rehabilitation services. However, there are concerns about health services' ability to meet this demand. While chiropractic care is gaining recognition for its benefits in treating older adults with musculoskeletal disorders, there is limited scientific literature on chiropractors' role and experiences in this area...
2024: PloS One
https://read.qxmd.com/read/38696494/continuity-of-care-between-dyslipidemia-patients-and-multiple-providers-a-cohort-study
#11
JOURNAL ARTICLE
Eunyoung Choi, Juhee Lee, Eunjung Choo, Eun Jin Jang, Iyn-Hyang Lee
OBJECTIVE: This study aimed to investigate the impacts of continuity of care (COC) between patients and multiple providers, i.e., doctors and community pharmacists, on clinical and economic outcomes. METHODS: This is a retrospective cohort study and analyzed Korean national claims data for ambulatory care setting between 2007 and 2018. Patients with dyslipidemia newly diagnosed in 2008 were identified. COC between providers and patients was computed using the continuity of care index (COCI)...
2024: PloS One
https://read.qxmd.com/read/38696477/association-of-chest-computed-tomography-severity-score-at-icu-admission-and-respiratory-outcomes-in-critically-ill-covid-19-patients
#12
JOURNAL ARTICLE
Ricardo Esper Treml, Tulio Caldonazo, Fábio Barlem Hohmann, Daniel Lima da Rocha, Pedro Hilton A Filho, Andréia L Mori, André S Carvalho, Juliana S F Serrano, Pedro A T Dall-Aglio, Peter Radermacher, João M Silva
OBJECTIVE: To evaluate the association of a validated chest computed tomography (Chest-CT) severity score in COVID-19 patients with their respiratory outcome in the Intensive Care Unit. METHODS: A single-center, prospective study evaluated patients with positive RT-PCR for COVID-19, who underwent Chest-CT and had a final COVID-19 clinical diagnosis needing invasive mechanical ventilation in the ICU. The admission chest-CT was evaluated according to a validated Chest-CT Severity Score in COVID-19 (Chest-CTSS) divided into low ≤50% (<14 points) and >50% high (≥14 points) lung parenchyma involvement...
2024: PloS One
https://read.qxmd.com/read/38696444/relapses-of-juvenile-idiopathic-arthritis-in-adulthood-a-monocentric-experience
#13
JOURNAL ARTICLE
Laura Scagnellato, Giacomo Cozzi, Ilaria Prosepe, Mariagrazia Lorenzin, Andrea Doria, Giorgia Martini, Francesco Zulian, Roberta Ramonda
INTRODUCTION: Our aim was to describe a monocentric cohort of young adult patients with juvenile idiopathic arthritis (JIA), assessing the risk of relapse after transition to adult care. METHODS: We conducted a retrospective study and collected clinical, serological, and demographic data of young adult patients (18-30 years old) referred to the Transition Clinic of a single Italian centre between January 2020 and March 2023. Patients with systemic-onset JIA were excluded...
2024: PloS One
https://read.qxmd.com/read/38696434/theoretically-based-factors-associated-with-stroke-family-caregiver-health
#14
JOURNAL ARTICLE
Cleopatra Kum, Holly J Jones, Elaine L Miller, Natalie Kreitzer, Tamilyn Bakas
PURPOSE: Most persons who have had strokes are cared for at home by family members-many of whom experience depressive symptoms and quality of life changes as a result of providing care. The objective of this study is to determine theoretically based factors associated with unhealthy days in stroke family caregivers. RESEARCH DESIGN AND METHODS: Secondary data analysis was conducted using baseline data from a large randomized controlled clinical trial testing the Telephone Assessment and Skill-Building Kit program with 254 family caregivers of persons who have had strokes...
May 2024: Rehabilitation Nursing: the Official Journal of the Association of Rehabilitation Nurses
https://read.qxmd.com/read/38696429/effects-of-mechanical-insufflation-exsufflation-on-ventilator-free-days-in-intensive-care-unit-subjects-with-sputum-retention-a-randomized-clinical-trial
#15
RANDOMIZED CONTROLLED TRIAL
Shota Kubota, Hideki Hashimoto, Yurika Yoshikawa, Kengo Hiwatashi, Takahiro Ono, Masaki Mochizuki, Hiromu Naraba, Hidehiko Nakano, Yuji Takahashi, Tomohiro Sonoo, Kensuke Nakamura
BACKGROUND: Mechanical insufflation-exsufflation (MI-E) facilitates extubation. However, its potential to reduce the duration of ventilator use remains unclear. Therefore, the present study investigated whether the use of MI-E shortened the duration of mechanical ventilation in patients with high sputum retention. METHODS: A randomized open-label trial was conducted at a single intensive care unit (ICU) in Japan between November 2017 and June 2019. Ventilated subjects requiring suctioning at least once every hour due to sputum retention were randomly assigned to the MI-E group or conventional care group...
2024: PloS One
https://read.qxmd.com/read/38696424/a-model-based-cost-utility-analysis-of-an-automated-notification-system-for-deteriorating-patients-on-general-wards
#16
JOURNAL ARTICLE
Emily Holmes, Huw Lloyd Williams, Dyfrig Hughes, Elke Naujokat, Bernd Duller, Christian P Subbe
BACKGROUND: Delayed response to clinical deterioration of hospital inpatients is common. Deployment of an electronic automated advisory vital signs monitoring and notification system to signal clinical deterioration is associated with significant improvements in clinical outcomes but there is no evidence on the cost-effectiveness compared with routine monitoring, in the National Health Service (NHS) in the United Kingdom (UK). METHODS: A decision analytic model was developed to estimate the cost-effectiveness of an electronic automated advisory notification system versus standard care, in adults admitted to a district general hospital...
2024: PloS One
https://read.qxmd.com/read/38696413/quality-of-life-and-its-associated-factors-in-chronic-kidney-disease-patients-undergoing-hemodialysis-from-a-peruvian-city-a-cross-sectional-study
#17
JOURNAL ARTICLE
Dana Machaca-Choque, Guimel Palomino-Guerra, Javier Flores-Cohaila, Edgar Parihuana-Travezaño, Alvaro Taype-Rondan, Sujey Gomez-Colque, Cesar Copaja-Corzo
OBJECTIVE: To assess quality of life and explore its associated factors in a group of patients with chronic kidney disease (CKD) undergoing hemodialysis in Peru. METHODOLOGY: We conducted a cross-sectional analysis of patients with CKD treated at two medical centers in Tacna, Peru; between July and September 2023. We conducted a survey via telephone interviews with eligible patients using the Short Form 36 (SF 36) to assess their quality of life. RESULTS: Of 257 patients with CKD undergoing hemodialysis, we successfully interviewed 207 (59...
2024: PloS One
https://read.qxmd.com/read/38696411/sociodemographic-clinical-characteristics-and-treatment-patterns-of-endometrial-cancer-cases-in-puerto-rico-during-the-period-2009-to-2015-a-retrospective-study
#18
JOURNAL ARTICLE
Yisel Pagán Santana, Maira Castañeda Ávila, Ruth Ríos Motta, Karen J Ortiz Ortiz
BACKGROUND: Over the past decades, the rising incidence rates of endometrial cancer have made it a significant public health concern for women worldwide. Treatment strategies for endometrial cancer vary based on several factors such as stage, histology, the patient's overall health, and preferences. However, limited amount of research on treatment patterns and potential correlations with sociodemographic characteristics among Hispanics is available. This study analyzes the treatment patterns for patients diagnosed with endometrial cancer in Puerto Rico...
2024: PloS One
https://read.qxmd.com/read/38696397/adverse-outcomes-in-patients-hospitalized-with-pneumonia-at-age-60-or-more-a-prospective-multi-centric-hospital-based-study-in-india
#19
MULTICENTER STUDY
Suman Kanungo, Uttaran Bhattacharjee, Aslesh O Prabhakaran, Rakesh Kumar, Prabu Rajkumar, Sumit Dutt Bhardwaj, Alok Kumar Chakrabarti, Girish Kumar C P, Varsha Potdar, Byomkesh Manna, Ritvik Amarchand, Avinash Choudekar, Giridara Gopal, Krishna Sarda, Kathryn E Lafond, Eduardo Azziz-Baumgartner, Siddhartha Saha, Lalit Dar, Anand Krishnan
BACKGROUND: Limited data exists regarding risk factors for adverse outcomes in older adults hospitalized with Community-Acquired Pneumonia (CAP) in low- and middle-income countries such as India. This multisite study aimed to assess outcomes and associated risk factors among adults aged ≥60 years hospitalized with pneumonia. METHODS: Between December 2018 and March 2020, we enrolled ≥60-year-old adults admitted within 48 hours for CAP treatment across 16 public and private facilities in four sites...
2024: PloS One
https://read.qxmd.com/read/38696394/hepcidin-in-contrast-to-heparin-binding-protein-does-not-portend-acute-kidney-injury-in-patients-with-community-acquired-septic-shock
#20
JOURNAL ARTICLE
Jon Olinder, Matilda Jovanovic Stjernqvist, Albin Lindén, Evelina Thaphikul Salomonsson, Martin Annborn, Heiko Herwald, Cecilia Rydén
BACKGROUND: Acute kidney injury (AKI) is a common and severe complication in patients treated at an Intensive Care Unit (ICU). The pathogenesis of AKI has been reported to involve hypoperfusion, diminished oxygenation, systemic inflammation, and damage by increased intracellular iron concentration. Hepcidin, a regulator of iron metabolism, has been shown to be associated with sepsis and septic shock, conditions that can result in AKI. Heparin binding protein (HBP) has been reported to be associated with sepsis and AKI...
2024: PloS One
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