keyword
https://read.qxmd.com/read/38700383/client-s-understanding-of-instructions-for-small-animals-in-a-veterinary-neurological-referral-center
#1
JOURNAL ARTICLE
Thomas Flegel, Katharina Dobersek, Sabrina Bayer, Lisa F Becker, Shenja Loderstedt, Irene C Böttcher, Josephine Dietzel, Carina Tästensen, Theresa Kalliwoda, Marie A Harkenthal, Andreas Kühnapfel, Vivian Weiß, Sarah Gutmann
BACKGROUND: It is not known how much information clients retrieve from discharge instructions. OBJECTIVE: To investigate client's understanding of discharge instructions and influencing factors. ANIMALS: Dogs and cats being hospitalized for neurological diseases. METHODS: Clients were presented questionnaires regarding their pet's disease, diagnostics, treatments, prognosis and discharge instructions at time of discharge and 2 weeks later...
May 3, 2024: Journal of Veterinary Internal Medicine
https://read.qxmd.com/read/38699306/autonomic-modulation-with-mindfulness-based-stress-reduction-in-chronic-kidney-disease-a-randomized-controlled-trial
#2
Jinhee Jeong, Yingtian Hu, Matias Zanuzzi, Dana DaCosta, Sabrina Li, Jeanie Park
BACKGROUND: Chronic kidney disease (CKD) is characterized by overactivation of the sympathetic nervous system (SNS) that leads to increased cardiovascular disease risk. Despite the deleterious consequences of SNS overactivity, there are very few therapeutic options available to combat sympathetic overactivity. AIM: To evaluate the effects of Mindfulness-Based Stress Reduction (MBSR) on SNS activity in CKD patients. METHOD: Participants with CKD stages III-IV were randomized to an 8-week MBSR program or Health Education Program (HEP; a structurally parallel, active control group)...
April 18, 2024: medRxiv
https://read.qxmd.com/read/38698661/impact-of-coronavirus-disease-2019-pandemic-in-children-with-functional-abdominal-pain-disorders-data-from-long-term-follow-up
#3
JOURNAL ARTICLE
Massimo Martinelli, Caterina Strisciuglio, Peter Lu, Michal Rozenfeld Bar Lev, Beate Beinvogl, Carlo Di Lorenzo, Sabrina Cenni, Samuel Nurko, Haley Pearlstein, Rachel Rosen, Raanan Shamir, Annamaria Staiano
OBJECTIVE: We aimed to compare symptom frequency and severity in children with functional abdominal pain disorders (FAPDs) and to evaluate anxiety, quality of life (QoL) and global health during Coronavirus disease 2019 (COVID-19) related quarantine and after 17 months. METHODS: Children diagnosed with FAPDs between October 2019 and February 2020 at 5 different centers were enrolled and prospectively interviewed during the COVID-19 quarantine and 17 months later when schools, hospital services, and routine activities had re-opened to the public...
May 2, 2024: Journal of Pediatric Gastroenterology and Nutrition
https://read.qxmd.com/read/38698519/first-report-of-colletotrichum-siamense-causing-anthracnose-in-oenocarpus-bacaba-in-brazil
#4
JOURNAL ARTICLE
Luana Bezerra Montelo, Marcio Akio Ootani, Sabrina Helena da Cruz Araujo, Dalmarcia de Souza Carlos Mourão, Raimundo Wagner de Souza Aguiar, Eugenio Eduardo Oliveira, Marcos Paz Saraiva Camara, Ana Gabriele Amaral, Cristiano Bueno de Moraes, Marcos Vinícius Giongo, Gil R Santos
Bacaba ( Oenocarpus bacaba Mart.) is a native palm tree from Brazilian Amazon and Cerrado biomes. This tree produces a small, rounded fruit with dark skin and approximately 1.5 mm thick pulp, extensively utilized for palm heart extraction, juices, and jellies (De Cól et al. 2021). However, several diseases can adversely impact fruit yield and quality. During the 2021 growing season, anthracnose symptoms were observed in Bacaba fruits, with a disease incidence of 58% in fruits collected from the Abreulândia (9°37'15″ S, 49°9'3″ W) and Gurupi (12°25'46" S; 49°16'42" W) municipalities in Tocantins state, Brazil...
May 2, 2024: Plant Disease
https://read.qxmd.com/read/38698213/the-use-of-peptides-for-immunodiagnosis-of-human-chagas-disease
#5
REVIEW
Anna Julia Ribeiro, Kamila Alves Silva, Lucas da Silva Lopes, Carlos Ananias Aparecido Resende, Carolina Alves Petit Couto, Isadora Braga Gandra, Isabela Amorim Gonçalves Pereira, Isabelle Caroline Dos Santos Barcelos, Sabrina Paula Pereira, Sandra Rodrigues Xavier, Grasiele de Sousa Viera Tavares, Juliana Martins Machado, Mariana Campos Da Paz, Miguel Angel Chávez-Fumagalli, Eduardo Antonio Ferraz Coelho, Rodolfo Cordeiro Giunchetti, Ana Thereza Chaves, Walderez Ornelas Dutra, Ana Alice Maia Gonçalves, Alexsandro Sobreira Galdino
Chagas disease, caused by the protozoa Trypanosoma cruzi, continues to be a serious public health problem in Latin America, worsened by the limitations in its detection. Given the importance of developing new diagnostic methods for this disease, the present review aimed to verify the number of publications dedicated to research on peptides that demonstrate their usefulness in serodiagnosis. To this end, a bibliographic survey was conducted on the PubMed platform using the keyword "peptide" or "epitope" combined with "Chagas disease" or "Trypanosoma cruzi"; "diagno*" or "serodiagnosis" or "immunodiagnosis", without period restriction...
May 2, 2024: Amino Acids
https://read.qxmd.com/read/38697719/-what-are-the-considerations-for-medium-prematurity
#6
JOURNAL ARTICLE
Marie Kassis, Sabrina Hedhili, Julie Armand, Marielle Yehouetome
Despite its high prevalence, moderate prematurity has been little studied in comparison with great or very great prematurity. In order to better understand the causes of this under-representation in the literature and in post-hospital care, this article proposes to analyze the historical and medical issues surrounding prematurity, and to investigate the different representations, by caregivers and parents, of the subject of intermediate prematurity. A necessary step in the evolution of practices.
2024: Soins. Pédiatrie, Puériculture
https://read.qxmd.com/read/38697429/kinetics-and-molecular-modeling-studies-on-the-inhibition-mechanism-of-gh13-%C3%AE-glycosidases-by-small-molecule-ligands
#7
JOURNAL ARTICLE
Mario Roberto Senger, Samara Graciane da Costa Latgé, Natalia Lidmar von Ranke, Gabriel Alves Souto de Aquino, Rafael Ferreira Dantas, Fernando Ariel Genta, Sabrina Baptista Ferreira, Floriano Paes Silva Junior
Alpha-glucosidase inhibitors play an important role in Diabetes Mellitus (DM) treatment since they prevent postprandial hyperglycemia. The Glycoside Hydrolase family 13 (GH13) is the major family of enzymes acting on substrates containing α-glucoside linkages, such as maltose and amylose/amylopectin chains in starch. Previously, our group identified glycoconjugate 1H-1,2,3-triazoles (GCTs) inhibiting two GH13 α-glycosidases: yeast maltase (MAL12) and porcine pancreatic amylase (PPA). Here, we combined kinetic studies and computational methods on nine GCTs to characterize their inhibitory mechanism...
April 30, 2024: International Journal of Biological Macromolecules
https://read.qxmd.com/read/38696726/congenital-myasthenic-syndromes-in-adults-clinical-features-diagnosis-and-long-term-prognosis
#8
JOURNAL ARTICLE
Julian Theuriet, Marion Masingue, Anthony Behin, Ana Ferreiro, Guillaume Bassez, Pauline Jaubert, Oriana Tarabay, Frédéric Fer, Antoine Pegat, Françoise Bouhour, Juliette Svahn, Philippe Petiot, Laurentiu Jomir, Guy Chauplannaz, Catherine Cornut-Chauvinc, Véronique Manel, Emmanuelle Salort-Campana, Shahram Attarian, Etienne Fortanier, Annie Verschueren, Ludivine Kouton, Jean-Philippe Camdessanché, Céline Tard, Armelle Magot, Yann Péréon, Jean-Baptiste Noury, Marie-Christine Minot-Myhie, Maud Perie, Frederic Taithe, Yacine Farhat, Anne-Laure Millet, Pascal Cintas, Guilhem Solé, Marco Spinazzi, Florence Esselin, Dimitri Renard, Sabrina Sacconi, Andra Ezaru, Edoardo Malfatti, Martial Mallaret, Laurent Magy, Eva Diab, Philippe Merle, Maud Michaud, Maxime Fournier, Aleksandra Nadaj Pakleza, Jean-Baptiste Chanson, Claire Lefeuvre, Pascal Laforet, Pascale Richard, Damien Sternberg, Rocio-Nur Villar-Quiles, Tanya Stojkovic, Bruno Eymard
Congenital myasthenic syndromes (CMS) are clinically and genetically heterogeneous diseases caused by mutations affecting neuromuscular transmission. Even if the first symptoms mainly occur during childhood, adult neurologists must confront this challenging diagnosis and manage these patients throughout their adulthood. However, long-term follow-up data from large cohorts of CMS patients are lacking and the long-term prognosis of these patients is largely unknown. We report the clinical features, diagnostic difficulties, and long-term prognosis of a French nationwide cohort of 235 adult patients with genetically confirmed CMS followed in 23 specialized neuromuscular centres...
May 2, 2024: Brain
https://read.qxmd.com/read/38696560/pandemics-and-their-accelerants-the-human-disease-how-we-create-pandemics-from-our-bodies-to-our-beliefs-sabrina-sholts-mit-press-2024-352-pp
#9
JOURNAL ARTICLE
Christos Lynteris
A well-researched account of the factors that drive pandemics misses an opportunity to indict broader social systems.
May 3, 2024: Science
https://read.qxmd.com/read/38695946/sphenopalatine-artery-pseudoaneurysm-masquerading-as-a-second-primary-maxillary-carcinoma
#10
JOURNAL ARTICLE
William Ansley, Smile Kajal, Sabrina Brar, Raj Lakhani, Rahul Jayaram, Alex Weller, Kate Hulley
PURPOSE: Maxillary sinus carcinomas usually present as a locally advanced disease at the time of diagnosis and it is extremely unusual to have a second primary maxillary carcinoma on the contralateral side after many years of completion of treatment of the first malignancy. We present here a case report of a sphenopalatine artery (SPA) pseudoaneurysm mimicking the second primary maxillary carcinoma. METHODS: We reviewed the literature for SPA pseudoaneurysm. RESULTS/CASE REPORT: This report describes the case of a 90-year-old man with a background of adenoid cystic carcinoma of the right maxillary sinus, diagnosed and treated with surgery and radiotherapy 14 years ago, who presented with a history of multiple episodes of epistaxis...
May 2, 2024: European Archives of Oto-rhino-laryngology
https://read.qxmd.com/read/38695232/-peritoneal-dialysis-network-in-north-east-italy-survey-about-the-peritoneal-catheter-exit-site-infection-management-and-comparison-with-ispd-guidelines
#11
MULTICENTER STUDY
Antonino Previti, Sabrina Milan Manani, Vincenzo Cosentini, Antonina Lo Cicero, Marta Guizzo, Monica Apolloni, Marina Cappellari, Sabina Rognini, Mery Zuccolo, Maria Grazia Virzì, Giovanni Gambaro
Introduction. The Triveneto Peritoneal Dialysis (PD) Network aims to bring together doctors and nurses who deal with PD in a collaborative network in which to exchange mutual knowledge and optimize the use of this method of replacing renal function. A topic of particular interest was the management of peritoneal catheter exit-site infection, given the recent publication of the new guidelines of the International Society of Peritoneal Dialysis (ISPD). Materials and methods. The survey concerned the criteria for carrying out nasal swab and exit-site, management of exuberant granulation tissue "Proud Flesh", treatment of exit-site infection (ESI), use of silver dressings, the role of subcutaneous tunnel ultrasound and cuff shaving...
April 29, 2024: Giornale Italiano di Nefrologia: Organo Ufficiale Della Società Italiana di Nefrologia
https://read.qxmd.com/read/38695225/-new-treatment-strategies-in-patients-with-heart-failure-with-reduced-ejection-fraction-beyond-neurohormonal-inhibition
#12
REVIEW
Luca Di Lullo, Cristina Galderisi, Carlo Lavalle, Marta Palombi, Antonio De Pascalis, Natale Di Belardino, Sabrina Iannotti, Vincenzo Barbera, Antonio Bellasi
Patients affected by heart failure (HF) with reduced ejection fraction (HFrEF) are prone to experience episodes of worsening symptoms and signs despite continued therapy, termed "worsening heart failure" (WHF). Although guideline-directed medical therapy is well established, worsening of chronic heart failure accounts for almost 50% of all hospital admissions for HF with consequent higher risk of death and hospitalization than patients with "stable" HF. New drugs are emerging as cornerstones to reduce residual risk of both cardiovascular mortality and readmission for heart failure...
April 29, 2024: Giornale Italiano di Nefrologia: Organo Ufficiale Della Società Italiana di Nefrologia
https://read.qxmd.com/read/38694605/cutting-edge-developments-in-spine-surgery-at-the-university-of-missouri
#13
JOURNAL ARTICLE
Ravi Nunna, Farzana Tariq, Michael Ortiz, Inamullah Khan, Sabrina Genovese, Paul Santiago
The treatment of spinal pathologies has evolved significantly from the times of Hippocrates and Galen to the current era. This evolution has led to the development of cutting-edge technologies to improve surgical techniques and patient outcomes. The University of Missouri Health System is a high-volume, tertiary care academic medical center that serves a large catchment area in central Missouri and beyond. The Department of Neurosurgery has sought to integrate the best available technologies to serve their spine patients...
2024: Missouri Medicine
https://read.qxmd.com/read/38693983/pulmonary-artery-aneurysm-case-report-and-experience-of-our-center
#14
JOURNAL ARTICLE
Maria Sabrina Ferrante, Calogera Pisano, Daniele Trombetti, Laura Asta, Claudia Altieri, Paolo Nardi, Giovanni Rivolo
No abstract text is available yet for this article.
March 2024: Polish Journal of Cardio-Thoracic Surgery
https://read.qxmd.com/read/38692406/intravenous-immunoglobulin-ivig-ameliorates-disease-in-a-murine-model-of-anti-laminin-332-mucous-membrane-pemphigoid
#15
JOURNAL ARTICLE
Sripriya Murthy, Sabrina Patzelt, Axel Künstner, Hauke Busch, Enno Schmidt, Christian D Sadik
Intravenous immunoglobulin (IVIg) is used to treat mucous membrane pemphigoid (MMP), although its therapeutic effectivity is not sufficiently supported by randomized controlled clinical trials and its mode of action is only insufficiently understood. We have examined the effect of IVIg in a mouse model of anti-laminin 332 MMP and found that IVIg ameliorates both cutaneous and mucosal inflammatory lesions. Our investigation into the modes of action of IVIg in MMP indicated effective antiinflammatory mechanisms beyond the enhanced degradation of IgG mediated through inhibition of the neonatal Fc receptor...
April 29, 2024: Journal of Investigative Dermatology
https://read.qxmd.com/read/38691655/cross-sectional-associations-between-prenatal-per-and-poly-fluoroalkyl-substances-and-bioactive-lipids-in-three-environmental-influences-on-child-health-outcomes-echo-cohorts
#16
JOURNAL ARTICLE
Himal Suthar, Tomás Manea, Dominic Pak, Megan Woodbury, Stephanie M Eick, Amber Cathey, Deborah J Watkins, Rita S Strakovsky, Brad A Ryva, Subramaniam Pennathur, Lixia Zeng, David Weller, June-Soo Park, Sabrina Smith, Erin DeMicco, Amy Padula, Rebecca C Fry, Bhramar Mukherjee, Andrea Aguiar, Sarah Dee Geiger, Shukhan Ng, Gredia Huerta-Montanez, Carmen Vélez-Vega, Zaira Rosario, Jose F Cordero, Emily Zimmerman, Tracey J Woodruff, Rachel Morello-Frosch, Susan L Schantz, John D Meeker, Akram N Alshawabkeh, Max T Aung
Prenatal per- and poly-fluoroalkyl substances (PFAS) exposure may influence gestational outcomes through bioactive lipids─metabolic and inflammation pathway indicators. We estimated associations between prenatal PFAS exposure and bioactive lipids, measuring 12 serum PFAS and 50 plasma bioactive lipids in 414 pregnant women (median 17.4 weeks' gestation) from three Environmental influences on Child Health Outcomes Program cohorts. Pairwise association estimates across cohorts were obtained through linear mixed models and meta-analysis, adjusting the former for false discovery rates...
May 1, 2024: Environmental Science & Technology
https://read.qxmd.com/read/38690424/use-of-a-novel-microbiome-modulator-improves-anticancer-immunity-in-a-murine-model-of-malignant-pleural-mesothelioma
#17
JOURNAL ARTICLE
Christophe Gattlen, Kirby R Frank, Damien N Marie, Aurélien Trompette, Louis-Emmanuel Chriqui, Yameng Hao, Etienne Abdelnour, Michel Gonzalez, Thorsten Krueger, Paul J Dyson, Sviatlana Siankevich, Christophe von Garnier, Niki D J Ubags, Sabrina Cavin, Jean Y Perentes
OBJECTIVE: Malignant pleural mesothelioma is a fatal disease and a clinical challenge, as few effective treatment modalities are available. Previous evidence links the gut microbiome to the host immunoreactivity to tumors. We thus evaluated the impact of a novel microbiome modulator compound (MMC) on the gut microbiota composition, tumor immune microenvironment, and cancer control in a model of malignant pleural mesothelioma. METHODS: Age- and weight-matched immunocompetent (n = 23) or athymic BALB/c mice (n = 15) were randomly assigned to MMC or no treatment (control) groups...
April 2024: JTCVS open
https://read.qxmd.com/read/38690326/correction-long-term-follow-up-and-safety-of-patients-after-an-upfront-therapy-with-letrozole-for-early-breast-cancer-in-routine-clinical-care-the-preface-study
#18
Carolin C Hack, Nicolai Maass, Bahriye Aktas, Sherko Kümmel, Christoph Thomssen, Christopher Wolf, Hans-Christian Kolberg, Cosima Brucker, Wolfgang Janni, Peter Dall, Andreas Schneeweiss, Frederik Marme, Matthias Ruebner, Anna-Katharin Theuser, Nadine M Hofmann, Sybille Böhm, Katrin Almstedt, Sara Kellner, Naiba Nabieva, Paul Gass, Marc W Sütterlin, Hans-Joachim Lück, Sabine Schmatloch, Matthias Kalder, Christoph Uleer, Ingolf Juhasz-Böss, Volker Hanf, Christian Jackisch, Volkmar Müller, Brigitte Rack, Erik Belleville, Diethelm Wallwiener, Achim Rody, Claudia Rauh, Christian M Bayer, Sabrina Uhrig, Chloë Goossens, Hanna Huebner, Sara Y Brucker, Lothar Häberle, Tanja N Fehm, Alexander Hein, Peter A Fasching
[This corrects the article DOI: 10.1055/a-2238-3153.].
February 2024: Geburtshilfe und Frauenheilkunde
https://read.qxmd.com/read/38690226/social-determinants-of-health-correlations-and-resource-usefulness-at-a-milwaukee-free-clinic-for-uninsured-individuals-a-cross-sectional-study
#19
JOURNAL ARTICLE
Jessica Miller, Adrianna Doucas, Hamsitha Karra, Suma K Thareja, Owen Bowie, Xiaowei Dong, Jennifer Terrell, Samuel Hernandez, Ana Mia Corujo-Ramirez, Nicole Xia, Sabrina Qi, Chiang-Ching Huang, Rebecca Lundh, Staci A Young
INTRODUCTION: Addressing social determinants of health (SDOH) is fundamental to improving health outcomes. At a student-run free clinic, we developed a screening process to understand the SDOH needs and resource utilization of Milwaukee's uninsured population. METHODS: In this cross-sectional study, we screened adult patients without health insurance ( N = 238) for nine traditional SDOH needs as well as their access to dental and mental health care between October 2021 and October 2022...
2024: Journal of Clinical and Translational Science
https://read.qxmd.com/read/38689351/strengthening-event-based-surveillance-ebs-a-case-study-from-afghanistan
#20
JOURNAL ARTICLE
Mohamed Mostafa Tahoun, Mohammad Nadir Sahak, Muzhgan Habibi, Mohamad Jamaluddin Ahadi, Bahara Rasoly, Sabrina Shivji, Ahmed Taha Aboushady, Pierre Nabeth, Mahmoud Sadek, Alaa Abouzeid
The sustained instability in Afghanistan, along with ongoing disease outbreaks and the impact of the COVID-19 pandemic, has significantly affected the country.During the COVID-19 pandemic, the country's detection and response capacities faced challenges. Case identification was done in all health facilities from primary to tertiary levels but neglected cases at the community level, resulting in undetected and uncontrolled transmission from communities. This emphasizes a missed opportunity for early detection that Event-Based Surveillance (EBS) could have facilitated...
April 30, 2024: Conflict and Health
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