Qubo Chen, Xiaoting Huang, Haiyan Zhang, Xuanting Jiang, Xuan Zeng, Wanhua Li, Hairong Su, Ying Chen, Fengye Lin, Man Li, Xiangyu Gu, Huihui Jin, Ruohan Wang, Dechang Diao, Wei Wang, Jin Li, Sufen Wei, Weizheng Zhang, Wofeng Liu, Zhiping Huang, Yusheng Deng, Wen Luo, Zuofeng Liu, Beiping Zhang
BACKGROUND: Tongue coating microbiota has aroused particular interest in profiling oral and digestive system cancers. However, little is known on the relationship between tongue coating microbiome and colorectal cancer (CRC). METHODS: Metagenomic shotgun sequencing was performed on tongue coating samples collected from 30 patients with CRC, 30 patients with colorectal polyps (CP), and 30 healthy controls (HC). We further validated the potential of the tongue coating microbiota to predict the CRC by a random forest model...
2024: Journal of Oral Microbiology