Yaxin Ding, Wenjie Sun, Mingwei Han, Ziyu Liu, Huarui Kang, Xiaohan Ma, Jiayu Wang, Hongrui Mu, Yuxiao Huang, Shiyuan Hou, Danni Sun, Xing Shen, Xingan Wu, Rongrong Liu
Colorectal cancer (CRC) is a prevalent and aggressive malignancy with high mortality rates and significant risks to human well-being. Population-wide screening for tumor suppressor genes and oncogenes shows promise for reducing the incidence and fatality of CRC. Recent studies have suggested that NLRX1, an innate immunity suppressor, may play a role in regulating chronic inflammation and tumorigenesis. However, further investigation is needed to understand the specific role of NLRX1 in CRC. To evaluate the impact of NLRX1 on migration, invasion, and metastasis, two human colon cancer cell lines were studied in vitro...
April 29, 2024: Medical Oncology