Yingqian Zhu, Ce Huang, Liang Zheng, Qingqing Li, Jianli Ge, ShaSha Geng, Miaomiao Zhai, Xin Chen, Huixiao Yuan, Yang Li, Wenwen Jia, Keping Sun, Yan Li, Tong Ye, Zhengmei Zhao, Hailiang Liu, Zhongmin Liu, Hua Jiang
BACKGROUND: Mesenchymal stem cells (MSCs) hold a great promise for cell-based therapy in the field of regenerative medicine. In this study, we aimed to evaluate the safety and efficacy of intravenous infusion of human umbilical cord-derived MSCs (HUC-MSCs) in patients with aging frailty. METHODS: In this randomized, double-blind, placebo-controlled trial, participants diagnosed with aging frailty were randomly assigned to receive intravenous administrations of HUC-MSCs or placebo...
April 29, 2024: Stem Cell Research & Therapy